TWAS
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Genes
Traits
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Traits
:
Body mass index (BMI)
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chr3:169,916,919-171,323,393
Best TWAS P=8.49e-09 · Best GWAS P=5.35e-13 conditioned to 9.62e-07
170M
170.2M
170.4M
170.6M
170.8M
171M
171.2M
171.4M
0
2
4
6
8
10
12
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Cells Transformed fibroblasts
EIF5A2
0.1
0
enet
26
0
0.42
0.99
-5.8
8.5e-09
-0.53
0.07
0.33
TRUE