Best TWAS P=8.78e-11 · Best GWAS P=8.3e-10 conditioned to 0.0788
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Lung | YEATS2-AS1 | 0.13 | 0.03 | enet | 27 | 0.07 | 3.3e-06 | 5.6 | -5.4 | 8.2e-08 | -0.64 | 0.10 | 0.85 | FALSE |
| 2 | GTEx | Pituitary | ECE2 | 0.52 | 0.30 | lasso | 7 | 0.23 | 1.5e-06 | 5.3 | 5.3 | 1.4e-07 | 0.14 | 0.13 | 0.74 | FALSE |
| 3 | METSIM | Adipose | MAP6D1 | 0.06 | 0.05 | bslmm | 473 | 0.06 | 2.3e-09 | 5.6 | 6.5 | 8.8e-11 | 0.68 | 0.16 | 0.84 | TRUE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ECE2 | 0.04 | 0.02 | blup | 61 | 0.03 | 3.5e-04 | 5.3 | 5.9 | 2.9e-09 | 0.15 | 0.01 | 0.98 | FALSE |
| 5 | The Cancer Genome Atlas | Lung Adenocarcinoma | PSMD2 | 0.09 | 0.02 | blup | 50 | 0.05 | 1.2e-06 | -3.1 | 5.5 | 3.6e-08 | 0.08 | 0.09 | 0.51 | TRUE |