Best TWAS P=9.97e-09 · Best GWAS P=1.8e-07 conditioned to 0.0511
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Breast Mammary Tissue | PCYT1A | 0.11 | 0.03 | lasso | 3 | 0.00 | 0.3920 | 5.2 | -5.2 | 2.4e-07 | -0.96 | 0.02 | 0.85 | FALSE |
2 | GTEx | Breast Mammary Tissue | UBXN7 | 0.20 | 0.00 | enet | 16 | 0.02 | 0.0352 | -3.7 | -5.7 | 1.0e-08 | -0.65 | 0.03 | 0.81 | TRUE |
3 | GTEx | Stomach | SLC51A | 0.13 | 0.06 | enet | 12 | 0.03 | 0.0193 | 4.8 | -5.4 | 8.0e-08 | -0.86 | 0.01 | 0.95 | FALSE |
4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | UBXN7 | 0.02 | 0.01 | blup | 45 | 0.02 | 0.0042 | 4.0 | -5.6 | 2.6e-08 | -0.76 | 0.02 | 0.38 | FALSE |