[Hub]/) : Traits : Body mass index (BMI) : ← →

chr4:24,621,706-26,118,755

Best TWAS P=1.41e-10 · Best GWAS P=2.02e-10 conditioned to 0.353

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	ANAPC4	0.32	0.40	lasso	13	0.40	7.3e-35	6.0	6.0	2.4e-09	0.95	0.02	0.98	FALSE
2	GTEx	Artery Aorta	ANAPC4	0.40	0.43	lasso	5	0.42	5.4e-25	6.0	6.0	1.6e-09	0.95	0.02	0.98	FALSE
3	GTEx	Artery Tibial	ANAPC4	0.37	0.42	enet	48	0.46	1.0e-39	6.0	5.9	4.2e-09	0.91	0.02	0.98	FALSE
4	GTEx	Brain Cortex	ANAPC4	0.33	0.24	enet	23	0.26	7.5e-08	5.8	5.7	1.5e-08	0.86	0.02	0.98	FALSE
5	GTEx	Brain Putamen basal ganglia	ANAPC4	0.25	0.03	lasso	7	0.04	3.6e-02	5.8	5.4	5.4e-08	0.88	0.05	0.58	FALSE
6	GTEx	Breast Mammary Tissue	ANAPC4	0.49	0.42	lasso	8	0.42	1.5e-23	6.0	6.4	1.4e-10	0.94	0.02	0.98	TRUE
7	GTEx	Breast Mammary Tissue (Male)	ANAPC4	0.49	0.30	enet	14	0.26	8.6e-07	6.0	6.1	9.7e-10	0.86	0.02	0.96	FALSE
8	GTEx	Breast Mammary Tissue (Female)	ANAPC4	0.30	0.28	lasso	8	0.19	2.2e-06	6.0	5.9	2.9e-09	0.95	0.02	0.98	FALSE
9	GTEx	Cells Transformed fibroblasts	ANAPC4	0.14	0.20	lasso	8	0.19	2.3e-14	6.0	6.0	1.6e-09	0.96	0.02	0.98	FALSE
10	GTEx	Colon Sigmoid	ANAPC4	0.28	0.27	enet	12	0.24	5.7e-09	5.8	5.7	1.0e-08	0.94	0.03	0.97	FALSE
11	GTEx	Colon Transverse	ANAPC4	0.36	0.38	lasso	8	0.41	5.5e-21	6.0	5.5	3.0e-08	0.94	0.02	0.98	FALSE
12	GTEx	Esophagus Gastroesophageal Junction	ANAPC4	0.26	0.22	enet	21	0.20	8.3e-08	6.0	5.6	1.9e-08	0.92	0.02	0.98	FALSE
13	GTEx	Esophagus Mucosa	ANAPC4	0.33	0.23	lasso	10	0.21	4.6e-14	6.0	5.8	8.4e-09	0.95	0.01	0.99	FALSE
14	GTEx	Esophagus Muscularis	ANAPC4	0.37	0.40	lasso	8	0.39	2.4e-25	6.0	6.0	1.7e-09	0.94	0.02	0.98	FALSE
15	GTEx	Heart Atrial Appendage	ANAPC4	0.18	0.12	lasso	9	0.10	3.4e-05	6.0	6.0	2.5e-09	0.95	0.01	0.99	FALSE
16	GTEx	Heart Left Ventricle	ANAPC4	0.13	0.10	lasso	7	0.07	1.6e-04	6.4	6.3	3.9e-10	0.98	0.01	0.98	FALSE
17	GTEx	Liver	ANAPC4	0.25	0.14	enet	16	0.02	1.1e-01	6.0	6.0	2.6e-09	0.77	0.02	0.90	FALSE
18	GTEx	Lung	ANAPC4	0.14	0.14	enet	11	0.13	4.4e-10	5.8	6.0	2.0e-09	0.94	0.02	0.98	FALSE
19	GTEx	Muscle Skeletal	ZCCHC4	0.13	0.11	lasso	4	0.11	2.7e-11	5.2	5.5	3.3e-08	0.83	0.08	0.92	FALSE
20	GTEx	Nerve Tibial	ANAPC4	0.35	0.43	enet	14	0.43	4.3e-33	6.0	6.0	1.5e-09	0.95	0.02	0.98	FALSE
21	GTEx	Pancreas	ANAPC4	0.35	0.21	lasso	13	0.19	1.8e-08	5.8	6.4	1.8e-10	0.88	0.02	0.98	FALSE
22	GTEx	Pituitary	ANAPC4	0.38	0.12	lasso	7	0.07	8.8e-03	6.4	6.4	1.5e-10	0.95	0.01	0.94	FALSE
23	GTEx	Skin Not Sun Exposed Suprapubic	ANAPC4	0.40	0.45	enet	28	0.44	1.5e-26	6.0	5.7	1.5e-08	0.93	0.02	0.98	FALSE
24	GTEx	Skin Sun Exposed Lower leg	ANAPC4	0.27	0.34	enet	23	0.34	4.4e-29	6.0	6.3	3.7e-10	0.93	0.02	0.98	FALSE
25	GTEx	Spleen	ANAPC4	0.41	0.28	enet	14	0.36	3.2e-10	5.1	5.7	1.2e-08	0.93	0.01	0.98	FALSE
26	GTEx	Stomach	ANAPC4	0.28	0.34	lasso	5	0.32	5.1e-16	6.0	6.0	2.0e-09	0.96	0.02	0.98	FALSE
27	GTEx	Testis	ANAPC4	0.12	0.10	lasso	5	0.08	2.3e-04	6.0	6.0	1.9e-09	0.95	0.02	0.97	FALSE
28	GTEx	Thyroid	ANAPC4	0.27	0.23	lasso	14	0.26	8.0e-20	6.0	5.6	2.0e-08	0.91	0.02	0.98	FALSE
29	METSIM	Adipose	ANAPC4	0.19	0.28	bslmm	552	0.28	3.5e-42	6.0	5.5	4.8e-08	0.92	0.02	0.98	FALSE
30	ROSMAP	Brain Pre-frontal Cortex	ANAPC4	0.19	0.27	lasso	11	0.27	3.5e-35	6.0	5.7	9.4e-09	0.94	0.02	0.98	FALSE
31	YFS	Blood	ANAPC4	0.22	0.28	bslmm	530	0.32	4.5e-109	6.0	5.5	4.0e-08	0.90	0.02	0.98	FALSE
32	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ANAPC4	0.03	0.05	enet	10	0.04	1.9e-05	6.0	5.7	1.2e-08	0.89	0.01	0.98	FALSE
33	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	ANAPC4	0.10	0.04	lasso	5	0.06	1.1e-03	4.9	5.5	4.7e-08	0.92	0.03	0.64	FALSE