TWAS
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Models
Genes
Traits
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Traits
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Body mass index (BMI)
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chr5:77,052,232-77,837,260
Best TWAS P=6.17e-09 · Best GWAS P=6.37e-08 conditioned to 0.215
77.1M
77.2M
77.3M
77.4M
77.5M
77.6M
77.7M
77.8M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Prostate Adenocarcinoma
AP3B1
0.05
0.02
blup
126
0.03
0.0005
5.1
-5.8
6.2e-09
0.80
0.02
0.91
TRUE
1
The Cancer Genome Atlas
Breast Invasive Carcinoma
AP3B1
0.02
0.00
blup
126
0.01
0.0182
-5.1
-5.5
2.9e-08
0.86
0.02
0.87
FALSE