Best TWAS P=8.87e-11 · Best GWAS P=4.59e-13 conditioned to 7.92e-05
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | METSIM | Adipose | PHF15 | 0.03 | 0.01 | bslmm | 298 | 0.01 | 6.5e-03 | -7.2 | -6.5 | 8.9e-11 | 0.66 | 0.00 | 0.97 | TRUE |
2 | METSIM | Adipose | SAR1B | 0.06 | 0.02 | bslmm | 288 | 0.03 | 3.1e-05 | 2.2 | 6.0 | 2.0e-09 | -0.22 | 0.51 | 0.06 | FALSE |
3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | SAR1B | 0.04 | 0.01 | enet | 4 | 0.02 | 2.5e-03 | -4.6 | 5.5 | 2.8e-08 | -0.56 | 0.00 | 0.89 | FALSE |