Best TWAS P=2.14e-11 · Best GWAS P=2.07e-13 conditioned to 3.46e-08
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | PCDHGA3 | 0.05 | 0.03 | lasso | 1 | 0.02 | 0.0037 | 5.3 | 5.2 | 1.5e-07 | -0.04 | 0.02 | 0.96 | TRUE |
| 2 | GTEx | Vagina | PURA | 0.52 | 0.05 | enet | 51 | 0.09 | 0.0036 | 4.2 | -5.5 | 5.0e-08 | -0.41 | 0.06 | 0.12 | FALSE |
| 3 | YFS | Blood | CXXC5 | 0.01 | 0.00 | bslmm | 244 | 0.01 | 0.0026 | 5.9 | -6.7 | 2.1e-11 | -0.36 | 0.06 | 0.35 | TRUE |