TWAS
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Traits
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Traits
:
Body mass index (BMI)
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chr5:138,349,164-141,590,358
Best TWAS P=2.14e-11 · Best GWAS P=2.07e-13 conditioned to 3.46e-08
138.5M
139M
139.5M
140M
140.5M
141M
141.5M
0
5
10
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
YFS
Blood
CXXC5
0.01
0.00
bslmm
244
0.01
0.0026
5.9
-6.7
2.1e-11
-0.36
0.06
0.35
TRUE
1
CommonMind
Brain Pre-frontal Cortex
PCDHGA3
0.05
0.03
lasso
1
0.02
0.0037
5.3
5.2
1.5e-07
-0.04
0.02
0.96
TRUE
2
GTEx
Vagina
PURA
0.52
0.05
enet
51
0.09
0.0036
4.2
-5.5
5.0e-08
-0.41
0.06
0.12
FALSE