Best TWAS P=7.92e-08 · Best GWAS P=1.41e-08 conditioned to 0.0314
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | PACRG | 0.22 | 0.13 | lasso | 10 | 0.16 | 5.8e-19 | -5.5 | -5.3 | 8.9e-08 | 0.86 | 0.02 | 0.98 | FALSE |
| 2 | GTEx | Testis | PARK2 | 0.38 | 0.12 | enet | 26 | 0.23 | 1.8e-10 | -5.4 | 5.2 | 1.7e-07 | -0.64 | 0.02 | 0.98 | FALSE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | PACRG | 0.24 | 0.26 | lasso | 5 | 0.27 | 2.9e-35 | -5.4 | -5.2 | 2.5e-07 | 0.87 | 0.04 | 0.96 | FALSE |
| 4 | The Cancer Genome Atlas | Breast Invasive Carcinoma | PACRG | 0.03 | 0.03 | lasso | 1 | 0.02 | 1.9e-05 | -5.2 | -5.2 | 1.6e-07 | 0.89 | 0.00 | 0.99 | FALSE |
| 5 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | PACRG | 0.11 | 0.09 | lasso | 5 | 0.10 | 8.9e-12 | -5.2 | -5.4 | 7.9e-08 | 0.84 | 0.01 | 0.99 | TRUE |
| 6 | The Cancer Genome Atlas | Thyroid Carcinoma | PACRG | 0.11 | 0.09 | lasso | 4 | 0.09 | 3.4e-09 | -5.1 | -5.1 | 2.9e-07 | 0.88 | 0.01 | 0.99 | FALSE |