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chr9:102,162,230-103,803,109

Best TWAS P=1.69e-12 · Best GWAS P=1.2e-12 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
11	GTEx	Skin Sun Exposed Lower leg	TEX10	0.27	0.27	lasso	8	0.28	7.0e-23	7.1	7.1	1.7e-12	1.00	0.01	0.99	TRUE
21	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	INVS	0.16	0.12	enet	8	0.08	2.8e-04	6.4	6.7	2.1e-11	0.77	0.12	0.83	FALSE
20	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	INVS	0.09	0.02	enet	11	0.04	4.0e-05	5.6	6.2	5.8e-10	0.66	0.03	0.77	FALSE
10	GTEx	Skin Sun Exposed Lower leg	INVS	0.19	0.06	enet	30	0.11	1.5e-09	6.6	6.2	6.4e-10	0.79	0.02	0.98	FALSE
9	GTEx	Skin Not Sun Exposed Suprapubic	TEX10	0.10	0.09	lasso	4	0.10	3.1e-06	4.6	6.0	1.6e-09	0.92	0.02	0.98	FALSE
4	GTEx	Cells Transformed fibroblasts	INVS	0.16	0.10	enet	17	0.17	8.0e-13	6.6	6.0	1.7e-09	0.61	0.16	0.84	FALSE
18	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	INVS	0.10	0.03	blup	107	0.07	4.0e-04	6.8	6.0	1.9e-09	0.89	0.02	0.96	FALSE
22	The Cancer Genome Atlas	Prostate Adenocarcinoma	INVS	0.09	0.04	enet	14	0.06	1.5e-06	5.6	5.9	3.8e-09	0.75	0.05	0.94	FALSE
7	GTEx	Heart Left Ventricle	INVS	0.11	0.05	enet	15	0.04	2.6e-03	2.3	5.9	4.2e-09	0.72	0.04	0.84	FALSE
2	GTEx	Artery Aorta	INVS	0.15	0.10	enet	19	0.12	4.9e-07	6.6	5.8	6.2e-09	0.72	0.16	0.81	FALSE
15	YFS	Blood	INVS	0.15	0.14	lasso	7	0.24	1.4e-77	2.5	5.8	6.2e-09	0.78	0.02	0.98	FALSE
16	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	INVS	0.27	0.05	lasso	8	0.13	3.4e-11	5.6	5.8	6.6e-09	0.68	0.17	0.83	FALSE
19	The Cancer Genome Atlas	Lung Adenocarcinoma	INVS	0.08	0.06	blup	106	0.07	7.0e-09	-4.3	5.8	8.4e-09	0.70	0.86	0.14	FALSE
8	GTEx	Muscle Skeletal	INVS	0.12	0.03	lasso	10	0.10	1.3e-09	6.6	5.7	1.1e-08	0.73	0.06	0.94	FALSE
5	GTEx	Esophagus Muscularis	INVS	0.21	0.16	lasso	5	0.22	8.9e-14	6.6	5.7	1.3e-08	0.73	0.17	0.83	FALSE
6	GTEx	Heart Atrial Appendage	INVS	0.08	0.03	lasso	3	0.04	4.9e-03	-4.6	5.6	2.8e-08	0.77	0.08	0.85	FALSE
17	The Cancer Genome Atlas	Breast Invasive Carcinoma	INVS	0.22	0.04	lasso	9	0.07	7.3e-15	6.4	5.5	4.7e-08	0.71	0.22	0.78	FALSE
13	GTEx	Whole Blood	INVS	0.07	0.02	enet	9	0.05	2.8e-05	1.8	5.5	5.0e-08	0.70	0.23	0.60	FALSE
3	GTEx	Brain Cerebellar Hemisphere	INVS	0.37	0.01	lasso	8	0.01	1.6e-01	5.6	5.4	5.2e-08	0.48	0.05	0.19	FALSE
1	CommonMind	Brain Pre-frontal Cortex	TEX10	0.18	0.10	lasso	7	0.12	2.2e-14	-4.2	5.4	6.3e-08	0.65	0.82	0.18	FALSE
23	The Cancer Genome Atlas	Thyroid Carcinoma	INVS	0.21	0.07	enet	13	0.18	4.0e-17	-4.3	5.4	8.4e-08	0.71	0.20	0.80	FALSE
12	GTEx	Thyroid	INVS	0.22	0.11	enet	18	0.18	5.0e-14	6.6	5.3	1.3e-07	0.65	0.16	0.84	FALSE
14	NTR	Blood	INVS	0.01	0.01	lasso	4	0.01	3.6e-04	-2.4	5.2	2.1e-07	0.57	0.21	0.47	FALSE