Best TWAS P=2.32e-14 · Best GWAS P=2.08e-19 conditioned to 1.14e-09
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Muscularis | NEGR1 | 0.13 | 0.04 | lasso | 3 | 0.05 | 5.1e-04 | -5.4 | 6.3 | 2.9e-10 | -0.66 | 0.71 | 0.12 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | NEGR1 | 0.24 | 0.15 | lasso | 8 | 0.22 | 1.3e-27 | 5.4 | 7.6 | 2.3e-14 | -0.48 | 0.35 | 0.65 | TRUE |