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chr1:71,163,715-73,435,171
Best TWAS P=2.32e-14 · Best GWAS P=2.08e-19 conditioned to 1.14e-09
71.5M
72M
72.5M
73M
73.5M
0
5
10
15
20
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
ROSMAP
Brain Pre-frontal Cortex
NEGR1
0.24
0.15
lasso
8
0.22
1.3e-27
5.4
7.6
2.3e-14
-0.48
0.35
0.65
TRUE
1
GTEx
Esophagus Muscularis
NEGR1
0.13
0.04
lasso
3
0.05
5.1e-04
-5.4
6.3
2.9e-10
-0.66
0.71
0.12
FALSE