Best TWAS P=1.03e-08 · Best GWAS P=6.55e-09 conditioned to 0.157
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | CCDC91 | 0.10 | 0.10 | lasso | 5 | 0.09 | 5.5e-07 | -5.1 | -5.2 | 1.8e-07 | 0.85 | 0.14 | 0.85 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | RP11-967K21.1 | 0.07 | 0.07 | lasso | 2 | 0.07 | 3.7e-06 | -5.7 | 5.7 | 1.5e-08 | -0.96 | 0.03 | 0.97 | FALSE |
| 3 | GTEx | Heart Atrial Appendage | RP11-967K21.1 | 0.08 | 0.09 | lasso | 1 | 0.08 | 2.3e-04 | -5.7 | 5.7 | 1.0e-08 | -0.91 | 0.03 | 0.94 | TRUE |
| 4 | GTEx | Skin Sun Exposed Lower leg | CCDC91 | 0.09 | 0.01 | enet | 8 | 0.01 | 2.6e-02 | -5.7 | -5.4 | 8.4e-08 | 0.85 | 0.05 | 0.91 | FALSE |