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chr13:114,302,502-115,106,996

Best TWAS P=6.82e-10 · Best GWAS P=2.48e-08 conditioned to 0.509

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	CDC16	0.17	0.17	lasso	4	0.19	3.6e-15	-5.5	-5.5	4.3e-08	0.99	0.01	0.99	FALSE
2	GTEx	Adipose Visceral Omentum	CDC16	0.12	0.11	lasso	4	0.09	1.5e-05	-5.6	-5.6	2.8e-08	0.98	0.01	0.99	FALSE
3	GTEx	Artery Aorta	CDC16	0.15	0.18	enet	10	0.17	1.6e-09	-5.5	-5.3	1.3e-07	0.97	0.01	0.99	FALSE
4	GTEx	Artery Coronary	CDC16	0.41	0.02	enet	5	0.02	6.9e-02	-5.0	-5.5	3.4e-08	0.91	0.02	0.94	FALSE
5	GTEx	Artery Tibial	CDC16	0.23	0.26	lasso	8	0.25	2.8e-19	-5.4	-5.5	4.9e-08	0.99	0.01	0.99	FALSE
6	GTEx	Brain Cerebellar Hemisphere	CDC16	0.17	0.10	lasso	9	0.17	3.5e-05	-5.5	-5.2	2.2e-07	0.92	0.02	0.97	FALSE
7	GTEx	Brain Cerebellum	CDC16	0.18	0.05	lasso	4	0.07	3.4e-03	-5.5	-5.2	1.8e-07	0.95	0.02	0.96	FALSE
8	GTEx	Breast Mammary Tissue	CDC16	0.25	0.28	lasso	6	0.26	6.9e-14	-5.6	-5.7	9.8e-09	0.97	0.01	0.99	FALSE
9	GTEx	Breast Mammary Tissue (Male)	CDC16	0.23	0.08	enet	11	0.09	3.8e-03	-5.3	-6.2	6.8e-10	0.85	0.03	0.87	TRUE
10	GTEx	Breast Mammary Tissue (Female)	CDC16	0.25	0.22	enet	28	0.22	3.6e-07	-5.6	-5.6	2.6e-08	0.92	0.02	0.98	FALSE
11	GTEx	Breast Mammary Tissue (Female)	UPF3A	0.32	0.16	lasso	13	0.17	1.2e-05	-5.5	-5.7	1.2e-08	0.91	0.02	0.98	FALSE
12	GTEx	Cells EBV-transformed lymphocytes	CDC16	0.14	0.09	lasso	3	0.10	2.9e-04	-5.5	-5.5	3.5e-08	0.99	0.01	0.98	FALSE
13	GTEx	Cells Transformed fibroblasts	CDC16	0.17	0.13	lasso	6	0.15	4.6e-11	-5.5	-5.4	6.4e-08	0.98	0.01	0.99	FALSE
14	GTEx	Colon Sigmoid	UPF3A	0.15	0.10	lasso	8	0.08	8.3e-04	-5.5	-5.6	2.2e-08	0.97	0.02	0.97	FALSE
15	GTEx	Colon Transverse	CDC16	0.18	0.23	lasso	5	0.21	3.2e-10	-5.6	-5.7	1.3e-08	0.98	0.01	0.99	FALSE
16	GTEx	Esophagus Gastroesophageal Junction	CDC16	0.09	0.05	lasso	2	0.02	5.7e-02	-5.6	-5.6	1.6e-08	1.00	0.02	0.90	FALSE
17	GTEx	Esophagus Gastroesophageal Junction	UPF3A	0.20	0.07	lasso	6	0.06	4.5e-03	-5.5	-5.4	5.4e-08	0.99	0.02	0.94	FALSE
18	GTEx	Esophagus Mucosa	CDC16	0.35	0.46	lasso	6	0.46	1.0e-33	-5.6	-5.5	3.7e-08	1.00	0.01	0.99	FALSE
19	GTEx	Lung	CDC16	0.16	0.21	lasso	5	0.19	9.6e-15	-5.5	-5.6	1.6e-08	0.99	0.01	0.99	FALSE
20	GTEx	Muscle Skeletal	CDC16	0.05	0.06	lasso	1	0.05	9.2e-06	-5.4	-5.4	5.9e-08	0.99	0.01	0.98	FALSE
21	GTEx	Nerve Tibial	CDC16	0.23	0.23	enet	19	0.26	9.5e-19	-5.5	-5.2	2.4e-07	0.95	0.01	0.99	FALSE
22	GTEx	Pancreas	CDC16	0.09	0.14	lasso	3	0.06	1.8e-03	-5.6	-5.6	2.6e-08	1.00	0.01	0.97	FALSE
23	GTEx	Prostate	CDC16	0.17	0.16	lasso	3	0.11	1.4e-03	-5.6	-5.6	2.8e-08	1.00	0.02	0.94	FALSE
24	GTEx	Skin Not Sun Exposed Suprapubic	CDC16	0.35	0.42	enet	33	0.45	7.9e-27	-5.5	-5.4	6.6e-08	0.96	0.01	0.99	FALSE
25	GTEx	Skin Sun Exposed Lower leg	CDC16	0.31	0.33	lasso	7	0.33	4.1e-28	-5.5	-5.5	4.9e-08	0.98	0.01	0.99	FALSE
26	GTEx	Spleen	CDC16	0.25	0.19	lasso	7	0.21	4.9e-06	-5.5	-5.6	2.5e-08	0.98	0.02	0.97	FALSE
27	GTEx	Testis	CDC16	0.32	0.30	enet	26	0.35	4.4e-16	-5.6	-5.8	8.4e-09	0.94	0.01	0.99	FALSE
28	GTEx	Thyroid	CDC16	0.12	0.13	lasso	2	0.11	8.2e-09	-5.5	-5.5	4.5e-08	1.00	0.01	0.99	FALSE
29	METSIM	Adipose	CDC16	0.18	0.27	enet	18	0.26	6.6e-39	-5.6	-5.6	2.8e-08	0.96	0.01	0.99	FALSE
30	NTR	Blood	CDC16	0.10	0.20	bslmm	209	0.20	3.1e-63	-5.5	-5.5	4.5e-08	1.00	0.01	0.99	FALSE
31	YFS	Blood	CDC16	0.28	0.54	enet	30	0.55	1.1e-220	-5.5	-5.6	2.4e-08	0.99	0.02	0.98	FALSE
32	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	CDC16	0.08	0.11	lasso	5	0.12	4.3e-10	-5.6	-5.5	4.5e-08	0.99	0.01	0.99	FALSE
33	The Cancer Genome Atlas	Breast Invasive Carcinoma	CDC16	0.01	0.01	blup	49	0.01	1.1e-03	-5.4	-5.8	7.5e-09	0.97	0.02	0.95	FALSE
34	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CDC16	0.05	0.08	lasso	4	0.08	7.2e-09	-5.5	-5.5	4.4e-08	0.99	0.01	0.99	FALSE
35	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CDC16	0.05	0.04	blup	49	0.05	2.0e-06	-5.5	-5.5	4.8e-08	0.95	0.01	0.99	FALSE
36	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	CDC16	0.04	0.01	blup	49	0.03	7.7e-03	-5.6	-5.5	4.6e-08	0.96	0.01	0.95	FALSE
37	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	CDC16	0.03	0.04	lasso	3	0.04	1.3e-05	-5.1	-5.7	1.4e-08	0.90	0.02	0.98	FALSE
38	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	CDC16	0.11	0.09	blup	49	0.09	1.8e-04	-5.5	-5.6	2.7e-08	0.98	0.01	0.97	FALSE
39	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	CDC16	0.07	0.03	blup	49	0.05	6.3e-03	-5.6	-5.4	5.5e-08	0.93	0.01	0.86	FALSE
40	The Cancer Genome Atlas	Thyroid Carcinoma	CDC16	0.06	0.09	lasso	3	0.09	3.3e-09	-5.6	-5.8	8.2e-09	0.98	0.01	0.99	FALSE