[Hub]/) : Traits : Weight :

chr14:21,250,124-22,662,856

Best TWAS P=6.44e-12 · Best GWAS P=1.03e-11 conditioned to 0.231

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Cells Transformed fibroblasts TOX4 0.19 0.06 lasso 7 0.05 6.6e-05 -6.7 -5.5 2.9e-08 0.92 0.00 0.99 FALSE
2 GTEx Testis TOX4 0.31 0.00 enet 24 0.04 6.8e-03 -6.8 -6.0 2.6e-09 0.65 0.01 0.84 FALSE
3 The Cancer Genome Atlas Breast Invasive Carcinoma METTL3 0.03 0.04 lasso 1 0.04 3.1e-08 -6.7 -6.7 2.7e-11 0.95 0.01 0.99 FALSE
4 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma METTL3 0.04 0.04 lasso 2 0.04 2.5e-05 -6.7 -6.7 2.7e-11 0.96 0.00 0.99 FALSE
5 The Cancer Genome Atlas Testicular Germ Cell Tumors METTL3 0.17 0.03 lasso 2 0.04 1.5e-02 -6.7 -6.9 6.4e-12 0.92 0.01 0.85 TRUE
6 The Cancer Genome Atlas Testicular Germ Cell Tumors RAB2B 0.12 0.04 blup 52 0.07 2.1e-03 -4.9 -6.0 2.3e-09 0.73 0.01 0.42 FALSE