Best TWAS P=3.43e-08 · Best GWAS P=4.3e-08 conditioned to 0.164
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | METSIM | Adipose | ADCY4 | 0.07 | 0.03 | lasso | 5 | 0.03 | 2.2e-05 | 5.4 | 5.5 | 3.4e-08 | 0.87 | 0.01 | 0.99 | TRUE |
2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ADCY4 | 0.06 | 0.06 | lasso | 6 | 0.09 | 3.0e-10 | 4.3 | 5.3 | 9.8e-08 | 0.81 | 0.01 | 0.99 | FALSE |