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chr16:24,162,204-25,620,010

Best TWAS P=1.7e-15 · Best GWAS P=4.3e-15 conditioned to 0.000215

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	METSIM	Adipose	SLC5A11	0.23	0.28	lasso	10	0.28	1.6e-42	-7.4	-7.4	1.0e-13	0.54	0.07	0.93	FALSE
2	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	SLC5A11	0.17	0.21	lasso	4	0.21	1.7e-17	-7.2	-7.6	3.3e-14	0.53	0.01	0.99	FALSE
3	The Cancer Genome Atlas	Breast Invasive Carcinoma	SLC5A11	0.12	0.17	enet	9	0.18	1.1e-35	-7.4	-7.7	1.6e-14	0.56	0.01	0.99	FALSE
4	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	SLC5A11	0.27	0.24	lasso	6	0.24	4.5e-12	-7.5	-7.8	4.3e-15	0.60	0.01	0.99	FALSE
5	The Cancer Genome Atlas	Colon Adenocarcinoma	SLC5A11	0.27	0.21	lasso	2	0.20	5.2e-12	-7.5	-7.5	6.1e-14	0.54	0.01	0.99	FALSE
6	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	SLC5A11	0.13	0.15	enet	8	0.15	6.6e-17	-7.4	-7.6	2.9e-14	0.52	0.01	0.99	FALSE
7	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SLC5A11	0.07	0.07	enet	7	0.06	1.7e-07	-7.4	-7.5	4.7e-14	0.55	0.01	0.99	FALSE
8	The Cancer Genome Atlas	Lung Adenocarcinoma	SLC5A11	0.14	0.20	enet	9	0.20	2.2e-23	-7.5	-7.5	4.5e-14	0.53	0.01	0.99	FALSE
9	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	SLC5A11	0.06	0.05	lasso	1	0.05	4.9e-06	-7.5	-7.5	8.5e-14	0.54	0.01	0.99	FALSE
10	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	SLC5A11	0.14	0.02	blup	62	0.07	1.4e-05	-7.4	-6.7	2.4e-11	0.36	0.01	0.97	FALSE
11	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	SLC5A11	0.30	0.33	lasso	2	0.32	2.8e-14	-7.4	-8.0	1.7e-15	0.62	0.01	0.99	TRUE
12	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	SLC5A11	0.54	0.32	lasso	6	0.30	1.8e-12	-7.2	-7.5	6.7e-14	0.59	0.01	0.99	FALSE
13	The Cancer Genome Atlas	Prostate Adenocarcinoma	SLC5A11	0.26	0.28	lasso	6	0.31	1.0e-32	-7.4	-7.5	5.4e-14	0.50	0.01	0.99	FALSE
14	The Cancer Genome Atlas	Soft Tissue Sarcoma	SLC5A11	0.17	0.21	lasso	3	0.18	4.9e-11	-7.4	-7.3	2.1e-13	0.52	0.01	0.99	FALSE
15	The Cancer Genome Atlas	Skin Cutaneous Melanoma	SLC5A11	0.20	0.05	lasso	4	0.04	2.8e-02	-7.5	-7.3	3.2e-13	0.51	0.01	0.75	FALSE
16	The Cancer Genome Atlas	Stomach Adenocarcinoma	SLC5A11	0.12	0.08	enet	7	0.07	7.0e-06	-7.4	-7.4	1.9e-13	0.50	0.01	0.99	FALSE
17	The Cancer Genome Atlas	Testicular Germ Cell Tumors	SLC5A11	0.21	0.10	lasso	5	0.07	2.2e-03	-7.4	-7.5	8.3e-14	0.53	0.01	0.97	FALSE
18	The Cancer Genome Atlas	Thyroid Carcinoma	SLC5A11	0.35	0.44	lasso	4	0.44	4.2e-47	-7.4	-7.5	5.1e-14	0.55	0.01	0.99	FALSE
19	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	SLC5A11	0.24	0.15	lasso	3	0.14	1.1e-04	-7.5	-7.5	8.2e-14	0.54	0.01	0.95	FALSE