Best TWAS P=3.95e-12 · Best GWAS P=4.3e-12 conditioned to 7.65e-08
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | GPRC5B | 0.07 | 0.04 | lasso | 4 | 0.03 | 1.3e-03 | -6.38 | 6.9 | 3.9e-12 | -0.08 | 0.15 | 0.63 | TRUE |
| 2 | GTEx | Skin Sun Exposed Lower leg | ACSM5 | 0.21 | 0.04 | lasso | 9 | 0.07 | 3.6e-06 | 0.95 | -5.2 | 2.0e-07 | 0.22 | 0.34 | 0.16 | TRUE |
| 3 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | IQCK | 0.03 | 0.03 | lasso | 3 | 0.02 | 7.2e-04 | -4.99 | -5.3 | 1.3e-07 | 0.07 | 0.02 | 0.96 | FALSE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | GPRC5B | 0.06 | 0.01 | blup | 38 | 0.01 | 2.4e-02 | -3.51 | -5.6 | 2.7e-08 | 0.05 | 0.01 | 0.08 | FALSE |