Best TWAS P=2.44e-09 · Best GWAS P=1.47e-07 conditioned to 0.471
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellar Hemisphere | MPHOSPH6 | 0.49 | 0.30 | enet | 12 | 0.31 | 8.5e-09 | 5.2 | 5.3 | 1.4e-07 | 0.86 | 0.01 | 0.98 | FALSE |
| 2 | GTEx | Esophagus Muscularis | MPHOSPH6 | 0.36 | 0.23 | lasso | 7 | 0.20 | 1.7e-12 | 5.1 | 5.1 | 2.9e-07 | 0.84 | 0.01 | 0.99 | FALSE |
| 3 | GTEx | Heart Atrial Appendage | MPHOSPH6 | 0.33 | 0.19 | enet | 27 | 0.21 | 5.4e-10 | 5.1 | 5.4 | 6.0e-08 | 0.76 | 0.01 | 0.99 | FALSE |
| 4 | GTEx | Heart Left Ventricle | MPHOSPH6 | 0.28 | 0.24 | lasso | 3 | 0.24 | 8.9e-13 | 5.1 | 5.2 | 2.6e-07 | 0.83 | 0.01 | 0.99 | FALSE |
| 5 | GTEx | Stomach | MPHOSPH6 | 0.41 | 0.10 | lasso | 7 | 0.09 | 3.5e-05 | 4.4 | 6.0 | 2.4e-09 | 0.81 | 0.02 | 0.97 | TRUE |