TWAS
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Traits
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chr2:68,925,733-70,360,950
Best TWAS P=2.16e-08 · Best GWAS P=2.58e-08 conditioned to 0.0134
69M
69.2M
69.4M
69.6M
69.8M
70M
70.2M
70.4M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
GFPT1
0.05
0.00
blup
67
0.02
5.9e-03
-4.8
5.6
2.2e-08
0.66
0.01
0.64
TRUE
1
GTEx
Cells Transformed fibroblasts
NFU1
0.10
0.07
lasso
2
0.03
2.0e-03
5.6
-5.6
2.6e-08
-1.00
0.00
0.99
FALSE
3
The Cancer Genome Atlas
Brain Lower Grade Glioma
GFPT1
0.12
0.05
blup
67
0.04
3.9e-05
-4.8
5.2
2.3e-07
0.54
0.01
0.98
FALSE