Best TWAS P=2.16e-08 · Best GWAS P=2.58e-08 conditioned to 0.0134
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | NFU1 | 0.10 | 0.07 | lasso | 2 | 0.03 | 2.0e-03 | 5.6 | -5.6 | 2.6e-08 | -1.00 | 0.00 | 0.99 | FALSE |
| 2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | GFPT1 | 0.05 | 0.00 | blup | 67 | 0.02 | 5.9e-03 | -4.8 | 5.6 | 2.2e-08 | 0.66 | 0.01 | 0.64 | TRUE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | GFPT1 | 0.12 | 0.05 | blup | 67 | 0.04 | 3.9e-05 | -4.8 | 5.2 | 2.3e-07 | 0.54 | 0.01 | 0.98 | FALSE |