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chr2:85,083,503-86,513,102

Best TWAS P=5.63e-09 · Best GWAS P=2.91e-07 conditioned to 0.174

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Artery Aorta	GGCX	0.23	0.22	lasso	6	0.23	5.5e-13	4.8	5.2	2.2e-07	0.86	0.01	0.98	FALSE
2	GTEx	Artery Tibial	GGCX	0.29	0.22	enet	14	0.24	6.3e-19	4.8	5.8	7.4e-09	0.85	0.02	0.97	FALSE
3	GTEx	Brain Cerebellar Hemisphere	GGCX	0.46	0.41	enet	16	0.48	5.3e-14	5.1	5.2	2.1e-07	0.94	0.01	0.98	FALSE
4	GTEx	Brain Cerebellum	GGCX	0.54	0.30	lasso	10	0.34	6.0e-11	4.8	5.4	7.5e-08	0.90	0.02	0.98	FALSE
5	GTEx	Breast Mammary Tissue (Male)	GGCX	0.10	0.00	enet	4	0.00	3.3e-01	4.6	5.1	2.8e-07	0.96	0.02	0.53	FALSE
6	GTEx	Cells EBV-transformed lymphocytes	GGCX	0.36	0.31	enet	18	0.29	4.5e-10	4.8	5.3	1.5e-07	0.95	0.01	0.98	FALSE
7	GTEx	Colon Transverse	GGCX	0.26	0.28	lasso	3	0.28	1.4e-13	4.8	5.1	2.6e-07	0.88	0.02	0.98	FALSE
8	GTEx	Esophagus Muscularis	GGCX	0.14	0.12	lasso	9	0.12	1.1e-07	4.8	5.6	2.6e-08	0.92	0.01	0.98	FALSE
9	GTEx	Muscle Skeletal	GGCX	0.10	0.04	enet	11	0.02	2.7e-03	4.8	5.7	1.4e-08	0.89	0.02	0.98	FALSE
10	GTEx	Nerve Tibial	GGCX	0.38	0.30	lasso	7	0.33	6.5e-24	4.8	5.6	2.6e-08	0.87	0.03	0.97	FALSE
11	GTEx	Pancreas	VAMP5	0.29	0.09	enet	4	0.05	3.2e-03	4.6	-5.2	1.5e-07	-0.45	0.04	0.47	FALSE
12	GTEx	Skin Not Sun Exposed Suprapubic	GGCX	0.13	0.04	enet	11	0.06	3.9e-04	4.8	5.8	6.4e-09	0.74	0.02	0.94	FALSE
13	GTEx	Skin Sun Exposed Lower leg	GGCX	0.15	0.11	lasso	3	0.18	7.9e-15	4.8	5.6	2.0e-08	0.76	0.03	0.96	FALSE
14	GTEx	Testis	GGCX	0.38	0.36	enet	25	0.40	8.6e-19	4.7	5.5	3.2e-08	0.84	0.03	0.96	FALSE
15	GTEx	Thyroid	GGCX	0.30	0.17	enet	10	0.23	1.4e-17	4.8	5.4	6.2e-08	0.84	0.02	0.97	FALSE
16	GTEx	Whole Blood	GGCX	0.15	0.14	lasso	4	0.15	1.7e-13	4.8	5.2	2.3e-07	0.90	0.02	0.97	FALSE
17	YFS	Blood	VAMP8	0.15	0.15	enet	37	0.18	2.2e-55	5.1	-5.2	2.0e-07	-0.89	0.01	0.98	FALSE
18	The Cancer Genome Atlas	Prostate Adenocarcinoma	GGCX	0.04	0.02	blup	44	0.02	2.7e-03	4.5	5.8	5.6e-09	0.72	0.03	0.89	TRUE