Best TWAS P=6.88e-15 · Best GWAS P=1.16e-17 conditioned to 0.00311
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | CADM2 | 0.05 | 0.06 | lasso | 10 | 0.06 | 1.3e-09 | 5.8 | 6.7 | 2.7e-11 | -0.32 | 1.00 | 0.00 | FALSE |
| 2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | CADM2 | 0.06 | 0.00 | blup | 339 | 0.00 | 2.7e-01 | -6.0 | -7.5 | 5.2e-14 | 0.75 | 0.02 | 0.73 | TRUE |
| 3 | The Cancer Genome Atlas | Lung Adenocarcinoma | CADM2 | 0.08 | 0.04 | lasso | 4 | 0.05 | 2.1e-06 | 7.2 | 7.8 | 8.9e-15 | -0.66 | 0.76 | 0.22 | FALSE |
| 4 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | CADM2 | 0.05 | 0.03 | lasso | 3 | 0.04 | 5.0e-05 | 7.2 | 7.8 | 6.9e-15 | -0.59 | 0.86 | 0.08 | TRUE |