TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Weight
:
←
→
chr3:120,799,666-122,252,204
Best TWAS P=1.58e-07 · Best GWAS P=4.98e-07 conditioned to 0.525
120.8M
121M
121.2M
121.4M
121.6M
121.8M
122M
122.2M
0
1
2
3
4
5
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Artery Coronary
IQCB1
0.21
0.14
enet
21
0.10
2.2e-04
4.9
-5.2
1.6e-07
-0.91
0.01
0.98
TRUE
3
GTEx
Thyroid
IQCB1
0.25
0.24
lasso
5
0.27
1.1e-20
5.0
-5.2
1.6e-07
-0.95
0.01
0.99
FALSE
2
GTEx
Brain Putamen basal ganglia
IQCB1
0.37
0.26
lasso
9
0.22
5.1e-06
4.9
-5.1
2.8e-07
-0.96
0.01
0.97
FALSE