Best TWAS P=1.58e-07 · Best GWAS P=4.98e-07 conditioned to 0.525
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Coronary | IQCB1 | 0.21 | 0.14 | enet | 21 | 0.10 | 2.2e-04 | 4.9 | -5.2 | 1.6e-07 | -0.91 | 0.01 | 0.98 | TRUE |
| 2 | GTEx | Brain Putamen basal ganglia | IQCB1 | 0.37 | 0.26 | lasso | 9 | 0.22 | 5.1e-06 | 4.9 | -5.1 | 2.8e-07 | -0.96 | 0.01 | 0.97 | FALSE |
| 3 | GTEx | Thyroid | IQCB1 | 0.25 | 0.24 | lasso | 5 | 0.27 | 1.1e-20 | 5.0 | -5.2 | 1.6e-07 | -0.95 | 0.01 | 0.99 | FALSE |