TWAS
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Models
Genes
Traits
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chr6:80,120,201-81,763,771
Best TWAS P=1.55e-10 · Best GWAS P=1.65e-07 conditioned to 0.00629
80.2M
80.4M
80.6M
80.8M
81M
81.2M
81.4M
81.6M
81.8M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Heart Atrial Appendage
RP11-250B2.6
0.20
0.00
enet
17
0.03
2.6e-02
-3.2
-6.4
1.6e-10
-0.43
0.05
0.47
TRUE
3
GTEx
Muscle Skeletal
RP11-250B2.6
0.07
0.04
lasso
5
0.04
4.2e-05
5.1
-5.4
6.8e-08
-0.98
0.01
0.98
FALSE
1
GTEx
Cells Transformed fibroblasts
BCKDHB
0.16
0.02
enet
42
0.04
3.7e-04
2.4
5.1
2.7e-07
0.47
0.30
0.50
FALSE