Best TWAS P=1.55e-10 · Best GWAS P=1.65e-07 conditioned to 0.00629
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | BCKDHB | 0.16 | 0.02 | enet | 42 | 0.04 | 3.7e-04 | 2.4 | 5.1 | 2.7e-07 | 0.47 | 0.30 | 0.50 | FALSE |
| 2 | GTEx | Heart Atrial Appendage | RP11-250B2.6 | 0.20 | 0.00 | enet | 17 | 0.03 | 2.6e-02 | -3.2 | -6.4 | 1.6e-10 | -0.43 | 0.05 | 0.47 | TRUE |
| 3 | GTEx | Muscle Skeletal | RP11-250B2.6 | 0.07 | 0.04 | lasso | 5 | 0.04 | 4.2e-05 | 5.1 | -5.4 | 6.8e-08 | -0.98 | 0.01 | 0.98 | FALSE |