Best TWAS P=8.06e-12 · Best GWAS P=7.23e-12 conditioned to 0.00402
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | TEX15 | 0.05 | 0.03 | enet | 9 | 0.02 | 6.8e-04 | 6.1 | 6.8 | 8.1e-12 | 0.70 | 0.06 | 0.92 | TRUE |
2 | ROSMAP | Brain Pre-frontal Cortex | TEX15 | 0.05 | 0.04 | lasso | 4 | 0.04 | 2.7e-06 | 5.8 | 6.2 | 7.2e-10 | 0.66 | 0.04 | 0.96 | FALSE |