TWAS hub - TEX15

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0540	0.0230	0.00280	0.031	0.019	0.023	0.019	0.004	9.3e-05	0.00200	6.8e-04	2e-03	8.7e-02
2	ROSMAP	Brain Pre-frontal Cortex	0.0473	0.0187	0.00042	0.041	0.022	0.043	0.025	0.043	4.8e-06	0.00061	3.0e-06	3e-04	2.8e-06

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Overall health rating	19.7	42.4	46.8	6.8	6.2
Medication: Bendroflumethiazide	16.1	24.5	26.1	5.1	4.8
Eye problems/disorders: Glaucoma	14.6	17.3	19.1	-3.9	-4.4
Fed-up feelings	11.3	20.6	24.4	4.1	4.9
Leg fat percentage (left)	11.0	39.7	47.2	6.9	5.7
Vascular/heart problems diagnosed by doctor	10.5	28.6	33.9	-4.8	-5.8
Qualifications: College or University degree	9.9	31.3	31.6	-5.6	-5.6
Leg fat percentage (right)	9.8	35.4	43.7	6.6	5.2
Qualifications: None of the above	9.7	20.7	27.2	5.2	3.8
Medication for pain relief, constipation, heartburn	9.5	16.3	17.4	-4.2	-3.9
Alcohol intake frequency.	9.4	21.8	23.2	4.5	4.8
Hypertension (Self-reported)	9.4	26.2	31.5	4.6	5.6
Commuting to job workplace: Cycle	9.4	11.3	14.5	-3.8	-2.8
Body fat percentage	9.1	35.9	44.7	6.7	5.2
Medication: Simvastatin	8.9	13.0	15.1	3.3	3.9
Medication: Aspirin	8.9	11.6	12.3	3.3	3.5
Leg fat mass (left)	8.9	34.7	41.6	6.4	5.3
Frequency of unenthusiasm / disinterest in last 2 weeks	8.7	11.7	13.1	3.6	3.2
High blood pressure	8.7	24.2	29.3	4.4	5.4
Medication for cholesterol, blood pressure or diabetes	8.5	14.1	14.2	-3.8	-3.7
Verbal and Numeric Reasoning (VNR)	8.2	19.6	21.9	-4.7	-4.2
Emphysema/chronic bronchitis	8.1	9.1	10.3	2.8	3.2
Leg fat mass (right)	8.1	31.3	38.1	6.2	4.9
Waist circumference	7.9	28.8	36.7	6.1	4.6
Medication: Blood pressure	7.9	15.1	18.7	3.4	4.3
Body mass index (BMI)	7.8	33.1	38.2	6.2	5.3
Arm fat percentage (left)	7.8	31.3	37.7	6.1	5.0
Whole body fat mass	7.7	31.9	40.1	6.3	4.9
Illnesses of father: High blood pressure	7.7	9.5	11.0	3.3	2.8
Trunk fat percentage	7.6	30.4	38.1	6.2	4.8
Arm fat percentage (right)	7.6	30.1	36.7	6.1	4.8
Medication: Atenolol	7.4	9.3	10.9	3.3	2.8
Illnesses of siblings	7.4	10.4	11.2	-3.1	-3.3
Medication: Aspirin	7.4	9.7	10.1	3.0	3.2
Intelligence (Savage-Jansen 2018)	7.3	22.5	28.9	-5.4	-4.0
BMI	7.3	42.2	46.7	6.8	6.1
Medication: Metformin	7.3	10.3	10.3	3.2	3.2
Unable to work because of sickness or disability	7.1	9.2	10.0	2.9	3.2
Trunk fat mass	7.0	29.9	37.0	6.1	4.8
Medication for cholesterol	6.9	10.5	10.8	-3.2	-3.3
Glaucoma (self-reported)	6.7	7.9	9.0	-2.6	-3.0
Arm fat mass (left)	6.7	27.6	33.5	5.8	4.7
Cardiovascular Disease	6.6	21.7	25.2	4.3	5.0
Qualifications: A levels/AS levels or equivalent	6.6	14.6	15.8	-4.0	-3.7
Average weekly red wine intake	6.6	9.8	10.0	-3.1	-3.2
Diabetes (father)	6.5	8.0	9.1	3.0	2.6
Diabetes (self-reported)	6.5	10.1	10.6	3.2	3.1
Arm fat mass (right)	6.5	26.6	33.3	5.8	4.5
Financial difficulties in last 2 years	6.4	8.6	9.5	3.1	2.8
Fluid intelligence score	6.4	13.3	16.3	-4.0	-3.2
Angina (self-reported)	6.4	8.4	8.8	2.8	3.0
Mood swings	6.4	11.6	12.4	3.5	3.3
Depressed Affect (Nagel 2018)	6.2	13.0	13.5	3.7	3.5
Taking other prescription medications	6.2	9.6	10.4	3.0	3.2
Number of treatments/medications taken	6.1	11.0	12.5	3.1	3.5
Townsend deprivation index at recruitment	6.0	8.5	8.5	2.9	2.9
Mouth/teeth dental problems: Loose teeth	5.8	6.9	7.7	2.8	2.5
Medication: Paracetamol	5.8	9.0	9.7	3.1	2.9
Stomach or abdominal pain in last month	5.7	7.1	7.8	2.5	2.8
Age at first live birth	5.6	10.0	11.5	-3.4	-2.9
Body Mass Index (BMI) (2010)	5.5	7.5	8.1	2.8	2.6
Number of live births	5.5	7.8	8.0	2.8	2.7
Illnesses of siblings: Diabetes	5.5	6.8	8.1	2.4	2.8
Eye problems/disorders: None of the above	5.4	6.3	7.9	2.1	2.8
Fasting Glucose	5.2	6.3	6.7	2.4	2.6
Medication: Paracetamol	5.2	8.6	11.1	3.3	2.5
Medication: Blood pressure	5.2	9.2	10.0	3.2	2.9
Medication: Cholesterol lowering	5.1	7.9	8.4	2.9	2.7
Neck or shoulder pain in last month	5.1	7.2	8.5	2.9	2.5
Pack years adult smoking proportion	5.0	7.7	8.7	3.0	2.6
Diabetes diagnosed by doctor	5.0	8.3	8.5	2.9	2.8
Number of self-reported non-cancer illnesses	5.0	8.7	11.9	2.3	3.5
Type 2 Diabetes (T2D) (2018)	4.9	9.2	9.4	3.0	3.1
Type 2 Diabetes (T2D) (2012)	4.8	5.5	6.2	2.2	2.5
High blood pressure (mother)	4.8	6.7	6.7	2.6	2.6
Migraine (self-reported)	4.8	5.9	7.7	2.8	2.0
Age started oral contraceptive pill	4.7	5.8	6.1	-2.5	-2.4
Current tobacco smoking	4.6	7.6	9.1	3.0	2.5
Qualifications: nursing, teaching	4.5	7.0	8.4	-2.4	-2.9
Angina	4.2	5.6	5.9	2.3	2.4
Frequency of tiredness / lethargy in last 2 weeks	4.0	6.5	7.6	2.8	2.3
High blood pressure (siblings)	4.0	5.8	6.1	2.4	2.5
Long-standing illness, disability or infirmity	4.0	6.2	8.4	2.0	2.9
Smoking status: Current	4.0	6.4	7.7	2.8	2.3
Heart attack/myocardial infarction (self-reported)	3.9	5.1	5.6	2.1	2.4
Weight	3.8	18.8	23.2	4.8	3.8
Multivitamins +/- minerals	3.7	4.7	8.1	2.8	1.2
Average weekly champagne plus white wine intake	3.6	5.0	5.9	-2.0	-2.4
Wheeze or whistling in the chest in last year	3.5	6.3	6.6	2.6	2.4
Heart attack	3.4	4.3	4.8	2.0	2.2
Seen a psychiatrist for nerves, anxiety, tension or depression	3.4	4.5	6.2	1.6	2.5
High cholesterol (Self-reported)	3.4	6.1	6.4	2.4	2.5
Pack years of smoking	3.4	4.9	5.7	2.4	2.1
Mean Putamen Volume	3.3	3.8	3.8	-1.9	-2.0
Alcohol usually taken with meals	3.3	5.4	9.3	-1.2	-3.0
Hearing aid user	3.3	3.8	6.8	2.6	0.9
Illnesses of father: Heart disease	3.2	4.5	6.8	1.5	2.6
Illnesses of father: None of the above (group 1)	3.2	4.0	4.1	-2.0	-1.9
Wears glasses or contact lenses	3.2	3.7	3.9	2.0	1.9
Hip circumference	3.1	13.4	17.3	4.2	3.1
Number of full sisters	3.1	3.7	4.3	1.8	2.1
Tinnitus: Yes, but not now, but have in the past	3.0	3.2	3.9	-2.0	-1.6
Alzheimer’s Disease (in father)	2.9	3.1	3.7	-1.6	-1.9
Alcohol intake versus 10 years previously	2.9	4.3	4.9	1.9	2.2
Pain all over the body in last month	2.8	3.0	3.0	1.7	1.7
Hypothyroidism (self reported)	2.7	6.1	7.7	2.1	2.8
Bilateral oophorectomy (both ovaries removed)	2.7	3.2	4.7	2.2	1.3
Pulse rate	2.7	4.6	4.8	2.2	2.1
Shortness of breath walking on level ground	2.7	3.2	5.0	2.2	1.2
Pulse rate, automated reading	2.7	8.6	8.7	3.0	2.9
Loneliness, isolation	2.7	3.7	4.9	1.6	2.2
Mouth/teeth dental problems: Mouth ulcers	2.7	4.2	4.6	-2.0	-2.2
Tinnitus: Yes, now most or all of the time	2.7	3.2	4.0	-1.5	-2.0
Blood White Count	2.5	18.3	19.1	4.4	4.2
Noisy workplace	2.4	3.0	3.8	2.0	1.5
Illnesses of mother	2.4	2.9	2.9	-1.7	-1.7
Age at last live birth	2.4	3.4	3.6	-1.9	-1.8
Handedness (chirality/laterality): Left-handed	2.4	2.9	4.0	-2.0	-1.4
Ever had hysterectomy (womb removed)	2.3	2.6	4.2	2.1	0.9
Systolic blood pressure, automated reading	2.3	6.7	8.2	2.3	2.9
Diabetes (mother)	2.3	2.9	4.3	1.2	2.1
Prospective memory result	2.3	2.8	3.2	1.8	1.5
Mother’s age at death	2.3	2.9	3.7	-1.9	-1.5
Average weekly beer plus cider intake	2.3	3.3	5.9	0.9	2.4
Alcohol drinker status: Previous	2.3	2.7	3.5	1.4	1.9
Chronotype (morning person)	2.2	5.0	5.7	-2.4	-2.1
Forced expiratory volume in 1-second (FEV1)	2.2	7.3	8.0	-2.8	-2.5
Hypothyroidism/myxoedema (self-reported)	2.2	4.3	5.8	1.7	2.4
HDL Cholesterol	2.1	3.6	5.2	-2.3	-1.4
Forced vital capacity (FVC)	2.1	7.9	8.5	-2.9	-2.7
Diastolic blood pressure, automated reading	2.1	6.6	7.6	2.4	2.8
Ever depressed for a whole week	2.1	2.6	2.9	-1.7	-1.5
Qualifications: CSEs or equivalent	2.0	2.6	2.8	1.6	1.7
Mouth/teeth dental problems	2.0	3.1	4.2	-2.0	-1.4
Miserableness	2.0	3.4	4.7	2.2	1.5
Supplements: Fish oil (including cod liver oil)	2.0	2.7	3.0	1.5	1.7
Hearing difficulty/problems: Yes	1.9	2.9	4.9	2.2	1.0
Vitamin and mineral supplements	1.9	2.5	3.6	-1.9	-1.2
Supplements: Zinc	1.9	2.1	2.9	1.1	1.7
Medication: Co-codamol	1.9	2.2	3.4	1.0	1.9
Breastfed as a baby	1.9	2.3	2.6	-1.6	-1.4
Back pain experienced in last month	1.9	2.8	4.2	2.1	1.1
Cholesterol lowering medication	1.9	2.8	3.1	1.8	1.6
Pain experienced in last month	1.9	3.2	4.0	-2.0	-1.5
Schizophrenia vs Biploar Disorder	1.8	2.4	3.7	1.9	1.1
Falls in the last year	1.8	2.4	2.7	1.5	1.6
Forced expiratory volume in 1-second (FEV1), Best measure	1.8	5.8	6.0	-2.3	-2.5
Mouth/teeth dental problems: Bleeding gums	1.8	2.3	2.6	1.6	1.4
Forced vital capacity (FVC), Best measure	1.8	6.4	7.1	-2.4	-2.7
Alcohol drinker status: Never	1.8	2.2	3.2	1.8	1.1
Deep venous thrombosis (DVT) (self-reported)	1.8	2.3	2.8	1.3	1.7
Triglycerides	1.7	2.8	4.5	-1.1	-2.1
Medication for hormone replacement therapy	1.7	1.9	3.5	1.9	0.6
Worry too long after embarrassment	1.7	2.9	4.6	-2.1	-1.1
Neuroticism score	1.6	3.3	4.2	1.5	2.0
Blood clot in the leg (DVT)	1.6	2.0	2.6	1.2	1.6
Birth weight of first child	1.5	2.7	3.5	-1.4	-1.9
Medication: Amlodipine	1.5	2.1	2.6	1.2	1.6
Number of children fathered	1.5	1.7	2.6	-0.8	-1.6
Supplements: Vitamin C	1.5	1.8	2.2	1.2	1.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.5	1.7	2.1	1.4	1.2
Systolic Blood Pressure	1.4	7.2	10.7	2.0	3.3
Depression (Nagel 2018)	1.3	1.9	2.0	1.4	1.4
Alzheimer’s Disease (in mother)	1.3	1.5	1.5	1.2	1.2
Primary Biliary Cirrhosis	1.3	1.8	2.6	1.0	1.6
Neuroticism	1.3	3.2	4.2	1.5	2.1
Frequency of tenseness / restlessness in last 2 weeks	1.3	2.1	2.5	1.3	1.6
Waist Hip Ratio (WHR)	1.2	5.5	7.5	2.7	1.9
Hayfever, allergic rhinitis or eczema	1.2	2.5	2.6	-1.6	-1.6
Hair/balding pattern: Pattern 3	1.2	1.7	2.8	-0.8	-1.7
Mouth/teeth dental problems: Dentures	1.2	2.0	2.5	1.6	1.3
Chronic bronchitis/emphysema (mother)	1.2	1.4	2.3	1.5	0.7
Ever had stillbirth, spontaneous miscarriage or termination	1.2	1.3	2.0	1.4	0.7
Schizophrenia (2014)	1.1	2.4	2.5	1.6	1.5
Respiratory disease	1.1	2.4	2.5	1.6	1.5
Tanning	1.1	14.0	14.4	-3.7	-3.8
Sensitivity / hurt feelings	1.1	2.0	2.5	1.2	1.6
Comparative body size at age 10	1.1	2.9	4.0	-2.0	-1.3
Illness, injury, bereavement, stress in last 2 years	1.1	1.3	1.9	-1.4	-0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.1	1.3	1.6	1.0	1.3
Breast cancer (self-reported)	1.1	1.3	2.6	-0.2	-1.6
Supplements: Calcium	1.1	1.2	2.3	-0.1	1.5
Father’s age at death	1.0	1.3	1.7	-1.3	-1.0
Peak expiratory flow (PEF)	1.0	2.4	2.7	-1.4	-1.6
Family relationship satisfaction	1.0	1.2	1.9	0.7	1.4
Financial situation satisfaction	1.0	1.2	1.5	1.2	1.0
Schizophrenia (2018)	0.9	1.9	2.2	1.3	1.5
Irritable Bowel Disease (IBD)	0.9	2.1	3.2	1.8	1.0
Ulcerative Colitis (UC)	0.9	1.7	2.4	1.6	1.0
Had menopause	0.9	1.1	1.8	-0.6	-1.3
Impedance of arm (right)	0.9	4.4	4.8	-2.0	-2.2
Loud music exposure frequency	0.9	1.0	1.8	-1.3	-0.4
Headache pain in last month	0.9	1.6	2.9	1.7	0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.9	1.8	2.0	-1.3	-1.4
Commuting to job workplace: Public transport	0.9	1.1	2.1	1.5	-0.2
Number of operations (self-reported)	0.9	1.3	1.8	1.3	0.9
Major Depression (MDD)	0.8	0.9	1.8	1.3	0.3
Medication: Levothyroxine sodium	0.8	1.4	1.6	1.3	1.1
Impedance of arm (left)	0.8	3.8	3.9	-1.9	-2.0
Standing height	0.8	8.0	9.4	-2.6	-3.1
Had major operations	0.8	1.0	1.4	-0.7	-1.2
Friendships satisfaction	0.8	1.0	2.0	-0.2	1.4
Ever taken oral contraceptive pill	0.8	0.9	0.9	-0.9	-1.0
Basal metabolic rate	0.8	4.2	5.2	2.3	1.8
Arm predicted mass (left)	0.8	4.2	5.4	2.3	1.7
Neuroticism (Nagel 2018)	0.7	1.7	2.6	0.9	1.6
Blood Red Count	0.7	6.9	7.2	2.7	2.6
Severe depression (siblings)	0.7	0.8	1.0	1.0	0.8
Leg fat-free mass (left)	0.7	3.6	4.3	2.1	1.7
Leg predicted mass (left)	0.7	3.8	4.5	2.1	1.7
Medication: Ramipril	0.7	0.9	1.7	0.5	1.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.1	1.6	0.8	1.3
Birth weight	0.7	1.4	2.1	-0.9	-1.4
Arm fat-free mass (right)	0.7	3.7	4.8	2.2	1.6
Smoking status: Previous	0.7	1.0	1.9	-1.4	-0.5
Mineral and other dietary supplements	0.7	0.9	1.3	-0.8	-1.1
Pain type(s) experienced in last month: Hip pain	0.7	0.8	1.3	0.6	1.1
Arm fat-free mass (left)	0.7	3.6	4.7	2.2	1.6
Heart disease (siblings)	0.7	0.9	1.5	0.5	1.2
Bipolar Disorder or Schizophrenia	0.6	1.5	1.9	1.1	1.4
Age at First Birth	0.6	0.9	1.2	-1.1	-0.7
Height	0.6	10.9	14.3	-2.8	-3.8
Other serious medical condition/disability diagnosed by doctor	0.6	0.7	1.2	0.6	1.1
Impedance of leg (right)	0.6	2.8	3.5	-1.4	-1.9
Maternal smoking around birth	0.6	0.9	1.1	1.0	0.9
Hearing difficulty/problems with background noise	0.6	1.0	1.1	0.9	1.0
Depression (self-reported)	0.6	0.8	1.3	0.5	1.1
Pulse wave Arterial Stiffness index	0.6	0.7	1.1	1.0	0.6
Pulse wave peak to peak time	0.6	0.7	1.0	-1.0	-0.6
Heart disease (mother)	0.6	0.7	0.9	1.0	0.7
Chest pain or discomfort	0.6	0.8	1.1	0.7	1.1
Leg fat-free mass (right)	0.6	3.2	3.5	1.9	1.7
Leg predicted mass (right)	0.6	3.1	3.4	1.9	1.7
Guilty feelings	0.6	0.9	1.2	0.8	1.1
Risk taking	0.6	0.8	1.2	-0.7	-1.1
Coronary Artery Disease (CAD)	0.5	0.7	1.0	-0.5	-1.0
Smoking Status	0.5	1.2	2.0	1.4	0.7
Frequency of depressed mood in last 2 weeks	0.5	0.7	1.2	0.4	1.1
Relative age of first facial hair	0.5	0.9	1.3	-1.1	-0.7
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	1.1	-1.0	-0.3
Ever unenthusiastic/disinterested for a whole week	0.5	0.7	0.9	-0.6	1.0
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.5	1.0	-0.3	-1.0
Medication: Lansoprazole	0.5	0.6	0.8	0.6	0.9
Lung cancer (father)	0.5	0.5	0.7	-0.6	-0.8
Qualifications: O levels/GCSEs or equivalent	0.5	0.8	1.3	-1.2	-0.6
Arm predicted mass (right)	0.5	2.7	3.7	1.9	1.3
Knee pain experienced in last month	0.5	0.8	1.0	1.0	0.8
Impedance of whole body	0.5	2.8	3.1	-1.6	-1.8
Worry (Nagel 2018)	0.4	0.8	1.3	-1.1	-0.5
Crohns Disease (2017)	0.4	0.8	1.0	1.0	0.8
Reaction Time	0.4	0.7	1.1	-0.5	-1.1
LDL Cholesterol	0.4	0.6	1.0	1.0	0.5
Neuroticism (2016)	0.4	0.5	0.8	0.5	0.9
Ever used hormone-replacement therapy (HRT)	0.4	0.5	0.7	-0.8	-0.5
Average weekly fortified wine intake	0.4	0.4	0.8	0.9	-0.2
Supplements: Glucosamine	0.4	0.5	0.5	-0.6	-0.7
Ever highly irritable/argumentative for 2 days	0.4	0.5	0.9	0.2	1.0
Mean time to correctly identify matches	0.4	0.8	1.2	-0.6	-1.1
Irritability	0.4	0.6	0.7	0.8	0.8
Lung FEV1/FVC ratio	0.3	1.5	2.7	1.6	0.6
Serious illness, injury or assault to yourself	0.3	0.3	0.4	-0.5	0.6
Chronic bronchitis/emphysema (father)	0.3	0.3	0.6	0.7	0.2
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	0.4	-0.6	-0.6
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.3	0.4	0.5	0.6
Tense / ‘highly strung’	0.3	0.6	0.9	0.4	1.0
Gout (self-reported)	0.3	0.4	0.7	0.8	0.4
Medication: Omeprazole	0.3	0.4	0.6	0.4	0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.3	0.4	0.5	0.6
Suffer from ‘nerves’	0.3	0.4	0.9	-0.9	0.0
Eye problems/disorders: Cataract	0.3	0.4	0.5	0.7	-0.5
Whole body water mass	0.3	1.5	2.0	1.4	1.0
Ever smoked	0.3	0.5	0.8	0.5	0.9
Breast Cancer	0.2	0.5	0.7	-0.9	-0.6
Prostate Cancer	0.2	0.3	0.6	0.8	0.2
Blood Eosinophil Count	0.2	1.3	1.4	1.1	1.2
Heel T-Score	0.2	1.3	1.6	-1.3	-1.0
Lung FVC	0.2	0.8	1.1	-0.7	-1.0
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	0.4	-0.1	-0.7
Impedance of leg (left)	0.2	0.8	1.0	-0.8	-1.0
Nervous feelings	0.2	0.5	0.9	-1.0	-0.1
Number of full brothers	0.2	0.3	0.6	-0.7	-0.1
Health satisfaction	0.2	0.3	0.5	-0.2	0.7
Medication: Ibuprofen	0.2	0.3	0.5	0.0	0.7
Whole body fat-free mass	0.2	1.2	1.6	1.3	0.9
Commuting to job workplace: Walk	0.2	0.2	0.4	-0.3	-0.6
Ever had prostate specific antigen (PSA) test	0.2	0.2	0.4	0.1	-0.6
Fractured/broken bones in last 5 years	0.2	0.3	0.4	-0.6	-0.4
Basal cell carcinoma (self-reported)	0.2	0.3	0.4	-0.2	-0.7
Ovarian Cancer	0.1	0.2	0.3	0.2	0.6
Bipolar Disorder (2011)	0.1	0.1	0.2	-0.5	0.1
Crohns Disease (2012)	0.1	0.2	0.2	-0.4	-0.4
HbA1C	0.1	0.1	0.1	0.4	-0.1
Ulcerative Colitis	0.1	0.1	0.3	0.5	-0.2
Hair Pigment	0.1	2.8	3.6	1.4	1.9
Average weekly spirits intake	0.1	0.1	0.2	0.0	0.5
Relative age voice broke	0.1	0.1	0.2	-0.5	-0.1
Age when periods started (menarche)	0.1	0.3	0.6	0.2	0.8
Past tobacco smoking	0.1	0.2	0.2	0.3	-0.5
Hair/balding pattern: Pattern 2	0.1	0.1	0.2	0.4	-0.1
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.2	0.3	0.4	0.5
Allergy	0.1	0.3	0.4	0.6	0.6
Time employed in main current job	0.1	0.1	0.1	-0.3	0.2
Happiness	0.1	0.1	0.2	-0.4	0.1
Exposure to tobacco smoke at home	0.1	0.1	0.2	-0.5	-0.3
Medication: Ventolin 100micrograms inhaler	0.1	0.1	0.3	0.5	-0.1
Exposure to tobacco smoke outside home	0.1	0.1	0.1	-0.2	-0.3
Medication: Seretide 50 evohaler	0.1	0.1	0.1	0.2	0.3
Comparative height size at age 10	0.1	0.3	0.5	-0.4	-0.7
Leg pain on walking	0.1	0.1	0.1	0.2	0.3
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.1	0.3	0.2	0.5
Commuting to job workplace: Car/motor vehicle	0.1	0.1	0.1	0.3	0.2
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.2	0.4	-0.0	0.7
Ever had bowel cancer screening	0.1	0.1	0.2	-0.3	-0.4
Osteoporosis (self-reported)	0.1	0.1	0.1	0.4	0.3
Medication: Lisinopril	0.1	0.1	0.1	0.0	-0.4
Bipolar Disorder (2018)	0.0	0.1	0.1	0.1	0.3
Alzheimer’s Disease (including proxy)	0.0	0.0	0.1	-0.0	0.3
Lupus	0.0	0.1	0.1	-0.2	-0.2
Rheumatoid Arthritis	0.0	0.0	0.0	0.2	0.0
Blood Platelet Count	0.0	0.2	0.3	0.5	-0.2
Allergy or Eczema	0.0	0.1	0.1	-0.3	-0.3
Hand grip strength (left)	0.0	0.0	0.0	0.0	0.1
Hand grip strength (right)	0.0	0.0	0.0	0.2	-0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.0	0.0	0.0	-0.1	-0.0
Sitting height	0.0	0.3	0.4	-0.6	-0.5
Number of incorrect matches in round	0.0	0.0	0.0	0.2	-0.0
Had other major operations	0.0	0.0	0.1	0.3	-0.1
Trunk fat-free mass	0.0	0.1	0.1	0.4	0.1
Worrier / anxious feelings	0.0	0.1	0.1	-0.3	0.1
Asthma	0.0	0.1	0.1	0.3	0.0
Trunk predicted mass	0.0	0.1	0.1	0.4	0.0
Length of working week for main job	0.0	0.1	0.1	0.3	-0.0
Hair/balding pattern: Pattern 4	0.0	0.1	0.1	-0.2	0.4
Pulse wave reflection index	0.0	0.0	0.1	-0.0	0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.0	0.0	0.0	0.2	-0.1
Medication: Allopurinol	0.0	0.0	0.1	0.1	0.2
Asthma (self-reported)	0.0	0.1	0.2	0.4	0.0
Osteoarthritis (self-reported)	0.0	0.0	0.1	-0.1	-0.2
Medication: Gliclazide	0.0	0.0	0.0	-0.0	-0.1
Medication: Atorvastatin	0.0	0.0	0.0	0.2	-0.1
Myopia	0.0	0.0	0.0	-0.2	-0.1
Medication: Omeprazole (e.g. Zanprol)	0.0	0.0	0.0	-0.1	0.1

Hub : Genes

TEX15

Models

Trait associations