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chr11:112,486,568-113,952,419

Best TWAS P=6.99e-10 · Best GWAS P=5.58e-09 conditioned to 0.231

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
8	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ANKK1	0.04	0.03	blup	67	0.04	6.3e-05	5.1	-6.2	7.0e-10	-0.84	0.05	0.92	TRUE
7	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	ANKK1	0.04	0.02	blup	66	0.03	5.0e-04	5.4	6.0	1.7e-09	0.87	0.02	0.93	FALSE
5	GTEx	Heart Left Ventricle	TTC12	0.39	0.24	enet	36	0.38	2.5e-21	5.8	6.0	2.0e-09	0.87	0.02	0.98	FALSE
13	The Cancer Genome Atlas	Testicular Germ Cell Tumors	TTC12	0.07	0.06	blup	48	0.04	1.6e-02	5.3	5.9	3.3e-09	0.93	0.01	0.73	FALSE
11	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	TTC12	0.36	0.30	lasso	3	0.29	6.0e-12	5.8	5.8	5.2e-09	1.00	0.01	0.99	FALSE
12	The Cancer Genome Atlas	Prostate Adenocarcinoma	TTC12	0.21	0.20	lasso	4	0.22	1.2e-22	5.8	5.8	8.5e-09	0.97	0.01	0.99	FALSE
3	GTEx	Breast Mammary Tissue	TTC12	0.46	0.30	lasso	7	0.40	8.1e-22	4.6	5.5	4.4e-08	0.80	0.27	0.73	FALSE
10	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	ANKK1	0.08	0.02	blup	66	0.04	5.6e-03	5.3	-5.3	1.1e-07	-0.78	0.04	0.79	FALSE
2	GTEx	Brain Nucleus accumbens basal ganglia	TTC12	0.28	0.14	lasso	13	0.11	5.8e-04	4.6	5.3	1.5e-07	0.71	0.13	0.64	FALSE
4	GTEx	Breast Mammary Tissue (Female)	TTC12	0.46	0.22	lasso	10	0.34	6.2e-11	-5.2	5.2	1.9e-07	0.82	0.03	0.97	FALSE
9	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	TTC12	0.37	0.22	enet	5	0.22	1.1e-12	5.3	5.2	2.5e-07	0.91	0.02	0.98	FALSE
1	GTEx	Brain Hypothalamus	RP11-159N11.4	0.44	0.06	lasso	19	0.03	7.5e-02	4.6	5.1	3.0e-07	0.63	0.10	0.29	FALSE
6	GTEx	Skin Not Sun Exposed Suprapubic	TTC12	0.49	0.29	lasso	10	0.51	6.5e-32	4.6	5.1	3.0e-07	0.81	0.23	0.77	FALSE