Best TWAS P=9.58e-09 · Best GWAS P=4.23e-09 conditioned to 0.00276
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | TTLL7 | 0.11 | 0.01 | enet | 13 | 0.01 | 3.1e-02 | -5.2 | -5.7 | 9.6e-09 | -0.61 | 0.07 | 0.92 | TRUE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | TTLL7 | 0.10 | 0.10 | lasso | 8 | 0.09 | 4.3e-12 | -5.5 | 5.5 | 2.8e-08 | 0.64 | 0.04 | 0.96 | FALSE |