Best TWAS P=2.02e-09 · Best GWAS P=1.14e-12 conditioned to 0.0118
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | BTBD7 | 0.16 | 0.01 | lasso | 8 | 0.04 | 3.6e-04 | -5.2 | 5.2 | 2.0e-07 | -0.58 | 0.10 | 0.88 | FALSE |
| 2 | GTEx | Colon Sigmoid | RIN3 | 0.24 | 0.17 | lasso | 6 | 0.11 | 9.3e-05 | -6.0 | 6.0 | 2.0e-09 | -0.02 | 0.00 | 0.99 | TRUE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | C14orf142 | 0.11 | 0.04 | enet | 7 | 0.05 | 7.2e-07 | 4.1 | -6.0 | 2.0e-09 | 0.22 | 0.36 | 0.30 | TRUE |
| 4 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | BTBD7 | 0.02 | 0.01 | blup | 72 | 0.02 | 6.8e-03 | -5.6 | 5.3 | 1.2e-07 | -0.80 | 0.01 | 0.90 | TRUE |