Best TWAS P=2.55e-09 · Best GWAS P=8.43e-12 conditioned to 5.32e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Mucosa | RP11-1017G21.6 | 0.14 | 0.04 | lasso | 3 | 0.02 | 8.6e-03 | -4.1 | -5.3 | 1.2e-07 | 0.03 | 0.06 | 0.76 | TRUE |
| 2 | METSIM | Adipose | TRAF3 | 0.04 | 0.02 | enet | 7 | 0.04 | 4.5e-06 | 5.4 | 6.0 | 2.6e-09 | 0.79 | 0.04 | 0.96 | TRUE |
| 3 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | CKB | 0.03 | 0.00 | blup | 34 | 0.02 | 1.4e-03 | 3.7 | -5.2 | 2.4e-07 | 0.03 | 0.01 | 0.30 | TRUE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | C14orf153 | 0.09 | 0.08 | blup | 38 | 0.09 | 6.2e-10 | -4.5 | -5.1 | 2.8e-07 | 0.04 | 0.01 | 0.96 | FALSE |