Best TWAS P=2.08e-08 · Best GWAS P=1.35e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | GSTM1 | 0.51 | 0.05 | blup | 434 | 0.26 | 1.4e-33 | -1.6 | 5.5 | 4.9e-08 | 0.35 | 0.93 | 0.04 | FALSE |
| 2 | YFS | Blood | GNAI3 | 0.43 | 0.44 | lasso | 11 | 0.50 | 2.3e-192 | 5.7 | -5.6 | 2.1e-08 | -0.95 | 0.00 | 1.00 | TRUE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | GSTM2 | 0.09 | 0.01 | blup | 38 | 0.06 | 3.8e-07 | -2.2 | 5.2 | 2.7e-07 | 0.36 | 0.04 | 0.07 | TRUE |