Best TWAS P=1.35e-10 · Best GWAS P=5e-10 conditioned to 0.112
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | WNT2B | 0.43 | 0.46 | enet | 44 | 0.47 | 7.4e-64 | -6.1 | -5.8 | 6.7e-09 | 0.69 | 0.01 | 0.99 | FALSE |
| 2 | GTEx | Brain Cortex | WNT2B | 0.36 | 0.19 | lasso | 5 | 0.23 | 5.5e-07 | -5.9 | -5.9 | 3.3e-09 | 0.80 | 0.02 | 0.98 | FALSE |
| 3 | GTEx | Brain Frontal Cortex BA9 | WNT2B | 0.29 | 0.28 | lasso | 3 | 0.29 | 2.6e-08 | -6.1 | -6.3 | 3.1e-10 | 0.82 | 0.01 | 0.99 | FALSE |
| 4 | GTEx | Pituitary | ST7L | 0.31 | 0.18 | lasso | 7 | 0.18 | 3.0e-05 | -5.4 | -6.0 | 2.0e-09 | 0.86 | 0.01 | 0.97 | FALSE |
| 5 | GTEx | Skin Sun Exposed Lower leg | MOV10 | 0.05 | 0.02 | lasso | 5 | 0.02 | 1.1e-02 | -5.9 | -5.7 | 1.5e-08 | 0.85 | 0.02 | 0.95 | FALSE |
| 6 | GTEx | Testis | RLIMP2 | 0.35 | 0.00 | enet | 47 | 0.06 | 1.1e-03 | 1.9 | 5.4 | 7.4e-08 | -0.32 | 0.17 | 0.12 | FALSE |
| 7 | ROSMAP | Brain Pre-frontal Cortex | WNT2B | 0.34 | 0.40 | enet | 30 | 0.42 | 1.5e-59 | -5.9 | -5.7 | 1.0e-08 | 0.77 | 0.02 | 0.98 | FALSE |
| 8 | The Cancer Genome Atlas | Thyroid Carcinoma | MOV10 | 0.06 | 0.06 | lasso | 7 | 0.05 | 9.4e-06 | -6.2 | -6.4 | 1.3e-10 | 0.83 | 0.01 | 0.99 | TRUE |