Best TWAS P=9.1e-09 · Best GWAS P=2.79e-07 conditioned to 0.0334
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue (Male) | SNORD68 | 0.12 | 0.00 | enet | 28 | 0.03 | 8.2e-02 | -3.4 | -5.8 | 9.1e-09 | 0.60 | 0.02 | 0.21 | TRUE |
| 2 | GTEx | Cells Transformed fibroblasts | DBNDD1 | 0.32 | 0.20 | enet | 36 | 0.20 | 1.2e-14 | -3.8 | -5.4 | 7.7e-08 | 0.45 | 0.22 | 0.50 | FALSE |
| 3 | GTEx | Heart Atrial Appendage | DBNDD1 | 0.52 | 0.29 | enet | 27 | 0.27 | 9.8e-13 | -3.8 | -5.3 | 8.9e-08 | 0.44 | 0.22 | 0.50 | FALSE |
| 4 | GTEx | Nerve Tibial | DEF8 | 0.08 | 0.05 | enet | 6 | 0.05 | 3.2e-04 | 3.6 | -5.1 | 2.8e-07 | 0.20 | 0.13 | 0.08 | FALSE |
| 5 | GTEx | Pancreas | DBNDD1 | 0.26 | 0.16 | enet | 15 | 0.18 | 5.6e-08 | -3.8 | -5.3 | 1.1e-07 | 0.46 | 0.17 | 0.42 | FALSE |
| 6 | The Cancer Genome Atlas | Brain Lower Grade Glioma | DPEP1 | 0.06 | 0.01 | blup | 44 | 0.02 | 1.6e-03 | -5.1 | -5.5 | 3.9e-08 | 0.81 | 0.00 | 0.96 | FALSE |