Best TWAS P=3.98e-08 · Best GWAS P=1.84e-07 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | TRIM47 | 0.15 | 0.12 | enet | 13 | 0.14 | 2.8e-17 | 4.7 | -5.2 | 1.8e-07 | -0.95 | 0.01 | 0.99 | FALSE |
| 2 | GTEx | Brain Cerebellum | TRIM47 | 0.30 | 0.17 | lasso | 2 | 0.17 | 1.1e-05 | 5.1 | -5.1 | 2.9e-07 | -0.97 | 0.01 | 0.97 | FALSE |
| 3 | GTEx | Lung | RP11-552F3.10 | 0.12 | 0.02 | lasso | 2 | 0.03 | 4.4e-03 | 5.2 | -5.5 | 4.0e-08 | -0.96 | 0.02 | 0.51 | TRUE |
| 4 | GTEx | Nerve Tibial | TRIM65 | 0.25 | 0.10 | lasso | 6 | 0.16 | 8.7e-12 | 4.4 | 5.2 | 2.4e-07 | 0.89 | 0.02 | 0.98 | FALSE |