Best TWAS P=1.4e-08 · Best GWAS P=1.79e-09 conditioned to 5.16e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | ARFGEF2 | 0.09 | 0.05 | lasso | 8 | 0.10 | 9.2e-13 | -5.7 | 5.7 | 1.4e-08 | -0.41 | 0.02 | 0.98 | TRUE |
| 2 | GTEx | Skin Sun Exposed Lower leg | ZFAS1 | 0.07 | 0.03 | enet | 14 | 0.05 | 5.8e-05 | -4.9 | -5.4 | 7.5e-08 | 0.55 | 0.34 | 0.55 | FALSE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ARFGEF2 | 0.05 | 0.04 | lasso | 5 | 0.05 | 3.2e-06 | -5.7 | 5.5 | 4.9e-08 | -0.58 | 0.02 | 0.98 | FALSE |