[Hub]/) : Traits : Body fat percentage :

chr1:183,961,643-185,416,670

Best TWAS P=2.5e-09 · Best GWAS P=6.25e-09 conditioned to 0.00996

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex EDEM3 0.11 0.08 lasso 14 0.11 2.3e-13 5.0 -5.8 8.8e-09 -0.88 0.01 0.99 FALSE
2 GTEx Adipose Subcutaneous EDEM3 0.15 0.13 lasso 3 0.13 1.0e-10 5.7 -5.7 1.4e-08 -0.99 0.01 0.99 FALSE
3 GTEx Adipose Visceral Omentum EDEM3 0.15 0.07 lasso 4 0.08 7.4e-05 -5.3 -5.6 1.9e-08 -0.91 0.02 0.98 FALSE
4 GTEx Artery Aorta EDEM3 0.19 0.14 enet 12 0.15 9.6e-09 5.8 -5.8 8.4e-09 -0.98 0.01 0.99 FALSE
5 GTEx Artery Tibial EDEM3 0.23 0.16 enet 24 0.19 1.7e-14 5.8 -5.5 4.0e-08 -0.91 0.01 0.99 FALSE
6 GTEx Cells Transformed fibroblasts EDEM3 0.15 0.07 lasso 3 0.08 2.4e-06 5.8 -5.7 1.0e-08 -0.98 0.01 0.99 FALSE
7 GTEx Colon Sigmoid EDEM3 0.18 0.17 enet 12 0.13 2.1e-05 5.0 -5.7 1.4e-08 -0.97 0.01 0.99 FALSE
8 GTEx Colon Transverse EDEM3 0.15 0.08 lasso 6 0.09 6.2e-05 5.8 -5.7 9.6e-09 -0.96 0.02 0.98 FALSE
9 GTEx Esophagus Gastroesophageal Junction EDEM3 0.16 0.19 lasso 1 0.15 5.5e-06 5.7 -5.7 1.5e-08 -1.00 0.01 0.99 FALSE
10 GTEx Esophagus Mucosa EDEM3 0.09 0.02 enet 23 0.02 1.3e-02 -5.1 -5.1 2.8e-07 -0.63 0.03 0.91 FALSE
11 GTEx Esophagus Muscularis EDEM3 0.14 0.10 enet 16 0.08 1.5e-05 5.7 -5.6 1.8e-08 -0.98 0.01 0.99 FALSE
12 GTEx Lung EDEM3 0.15 0.10 lasso 6 0.09 1.5e-07 5.4 -5.6 1.8e-08 -0.96 0.02 0.98 FALSE
13 GTEx Nerve Tibial EDEM3 0.25 0.26 enet 20 0.28 4.8e-20 5.7 -5.8 9.1e-09 -0.99 0.01 0.99 FALSE
14 GTEx Skin Not Sun Exposed Suprapubic EDEM3 0.14 0.07 lasso 7 0.08 4.6e-05 5.8 -5.8 5.0e-09 -0.89 0.02 0.98 FALSE
15 GTEx Skin Sun Exposed Lower leg EDEM3 0.09 0.09 enet 12 0.10 2.1e-08 5.8 -5.7 1.0e-08 -0.95 0.01 0.99 FALSE
16 GTEx Testis EDEM3 0.20 0.07 lasso 7 0.08 1.3e-04 4.5 -5.5 4.7e-08 -0.94 0.03 0.97 FALSE
17 GTEx Thyroid EDEM3 0.11 0.07 enet 9 0.07 6.2e-06 -5.3 -5.9 4.5e-09 -0.95 0.02 0.98 FALSE
18 GTEx Uterus EDEM3 0.27 0.02 enet 20 0.13 1.6e-03 -3.8 -6.0 2.5e-09 -0.64 0.05 0.60 TRUE
19 The Cancer Genome Atlas Colon Adenocarcinoma EDEM3 0.08 0.08 blup 66 0.10 1.3e-06 5.4 -5.5 4.0e-08 -0.85 0.05 0.95 FALSE
20 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma EDEM3 0.05 0.06 enet 7 0.08 8.7e-10 4.5 -5.4 6.1e-08 -0.83 0.13 0.87 FALSE
21 The Cancer Genome Atlas Brain Lower Grade Glioma EDEM3 0.04 0.06 lasso 4 0.04 7.3e-06 5.7 -5.6 2.1e-08 -0.99 0.01 0.99 FALSE
22 The Cancer Genome Atlas Lung Adenocarcinoma EDEM3 0.04 0.04 blup 66 0.04 2.0e-05 5.0 -5.2 1.6e-07 -0.85 0.05 0.94 FALSE
23 The Cancer Genome Atlas Lung Squamous Cell Carcinoma EDEM3 0.02 0.02 blup 66 0.03 5.2e-04 5.4 -5.6 1.8e-08 -0.93 0.03 0.94 FALSE
24 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma EDEM3 0.05 0.05 blup 67 0.06 1.0e-04 -5.1 -5.5 4.2e-08 -0.96 0.02 0.97 FALSE
25 The Cancer Genome Atlas Rectum Adenocarcinoma EDEM3 0.23 0.06 blup 67 0.03 6.3e-02 -5.1 -5.5 4.9e-08 -0.85 0.01 0.55 FALSE