[Hub]/) : Traits : Body fat percentage :

chr1:201,158,976-202,607,593

Best TWAS P=1.11e-14 · Best GWAS P=5.97e-16 conditioned to 0.00942

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous SHISA4 0.09 0.04 lasso 3 0.03 1.5e-03 -4.9 -5.2 2.2e-07 -0.56 0.20 0.33 FALSE
2 GTEx Esophagus Muscularis LMOD1 0.16 0.09 enet 9 0.08 7.8e-06 8.0 -7.6 2.8e-14 -0.98 0.01 0.99 FALSE
3 GTEx Esophagus Muscularis RP11-307B6.3 0.20 0.12 lasso 3 0.12 5.6e-08 8.0 -7.5 6.8e-14 -0.97 0.01 0.99 FALSE
4 METSIM Adipose LMOD1 0.09 0.07 bslmm 496 0.07 4.8e-10 8.0 -7.4 1.4e-13 -0.97 0.01 0.99 FALSE
5 The Cancer Genome Atlas Breast Invasive Carcinoma LMOD1 0.02 0.01 blup 59 0.02 1.2e-04 7.9 -5.5 4.3e-08 -0.85 0.01 0.97 FALSE
6 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma LMOD1 0.07 0.06 blup 59 0.03 2.1e-02 8.0 -7.7 1.1e-14 -0.90 0.01 0.87 TRUE
7 The Cancer Genome Atlas Brain Lower Grade Glioma LMOD1 0.04 0.07 enet 6 0.05 9.4e-07 -5.1 -6.3 3.2e-10 -0.74 0.24 0.76 FALSE
8 The Cancer Genome Atlas Lung Adenocarcinoma LMOD1 0.04 0.01 blup 59 0.01 5.7e-02 7.9 -7.0 3.6e-12 -0.84 0.01 0.83 FALSE