Best TWAS P=8.57e-15 · Best GWAS P=9.23e-25 conditioned to 5.21e-12
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Ovary | LYPLAL1 | 0.20 | 0.11 | lasso | 3 | 0.07 | 9.3e-03 | 9.4 | -7.8 | 8.6e-15 | -0.64 | 0.07 | 0.41 | TRUE |
2 | GTEx | Testis | ZC3H11B | 0.33 | 0.28 | lasso | 3 | 0.27 | 1.5e-12 | -5.2 | -5.3 | 1.1e-07 | -0.26 | 1.00 | 0.00 | FALSE |