TWAS hub - LYPLAL1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0440	0.0200	1.4e-03	0.046	0.015	0.023	0.017	0.026	2.3e-06	5.4e-03	6.9e-04	3.2e-03	3.6e-04
2	GTEx	Artery Tibial	0.0586	0.0294	8.1e-03	-0.003	NA	0.000	NA	0.024	5.9e-01	NA	3.2e-01	NA	5.4e-03
3	GTEx	Ovary	0.2020	0.0830	3.7e-03	0.108	NA	0.027	NA	0.069	1.3e-03	NA	7.3e-02	NA	9.3e-03
4	YFS	Blood	0.0243	0.0104	2.3e-04	0.007	0.013	0.011	0.013	0.009	1.4e-03	3.2e-05	1.1e-04	2.6e-05	5.1e-04
5	TCGA	Bladder Urothelial Carcinoma	0.0400	0.0240	2.5e-03	0.004	0.014	0.009	NA	0.010	1.3e-01	1.9e-02	5.1e-02	NA	4.3e-02
6	TCGA	Breast Invasive Carcinoma	0.0407	0.0215	9.8e-07	0.039	0.030	0.033	NA	0.034	1.6e-08	6.4e-07	1.8e-07	NA	1.3e-07
7	TCGA	Head and Neck Squamous Cell Carcinoma	0.0565	0.0297	1.2e-05	0.035	0.033	0.034	NA	0.026	7.6e-05	1.2e-04	9.5e-05	NA	5.4e-04
8	TCGA	Kidney Renal Clear Cell Carcinoma	0.0883	0.0454	3.8e-06	0.067	0.046	0.048	NA	0.057	5.1e-08	6.3e-06	3.4e-06	NA	5.3e-07
9	TCGA	Brain Lower Grade Glioma	0.0906	0.0425	1.0e-08	0.081	0.081	0.074	NA	0.079	1.7e-09	1.8e-09	9.8e-09	NA	3.0e-09
10	TCGA	Lung Adenocarcinoma	0.0801	0.0423	7.4e-08	0.075	0.073	0.066	NA	0.070	4.1e-09	6.5e-09	3.3e-08	NA	1.5e-08
11	TCGA	Thyroid Carcinoma	0.1220	0.0560	8.3e-09	0.116	0.091	0.118	NA	0.114	2.3e-11	3.7e-09	1.6e-11	NA	3.2e-11

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Waist Hip Ratio (WHR)	5.9	26.4	204.5	2.7	3.8	14.3	-1.1	4.0	3.0	3.8	1.7	3.0	3.1	1.8
Pain experienced in last month	5.6	9.3	15.9	2.6	1.7	2.0	1.9	3.1	3.1	4.0	3.6	3.4	3.5	3.6
Medication: Ibuprofen	5.4	6.5	10.6	0.5	-2.8	-1.3	-3.0	-2.5	-2.6	-3.3	-2.7	-2.7	-2.8	-2.7
Number of children fathered	5.3	5.9	12.0	-1.3	-2.7	-0.6	-1.8	-2.3	-2.3	-3.5	-2.7	-2.4	-3.1	-2.7
Hair/balding pattern: Pattern 3	4.5	6.7	16.2	1.7	-0.7	2.8	-4.0	-3.1	-1.8	-2.7	-2.6	-2.7	-2.4	-2.7
Eye problems/disorders: Diabetes related eye disease	4.4	4.8	9.3	-0.6	-0.9	3.0	-2.1	-2.0	-1.7	-2.4	-2.7	-2.1	-2.5	-2.7
Diabetes (mother)	4.4	5.6	9.6	0.7	1.2	1.1	2.3	3.1	2.7	2.6	2.8	2.9	2.6	2.8
Headache pain in last month	4.4	7.5	13.6	-2.7	-1.8	-0.8	-0.5	-2.2	-2.8	-3.5	-3.6	-2.7	-3.7	-3.5
Medication: Ibuprofen (e.g. Nurofen)	3.9	4.9	9.2	-0.0	-1.9	-1.7	-2.3	-1.9	-2.1	-3.0	-2.5	-2.3	-2.6	-2.5
Hair/balding pattern: Pattern 4	3.9	9.5	16.6	-2.9	-0.6	-1.0	-1.8	-2.9	-3.8	-3.9	-3.6	-3.3	-4.1	-3.6
Neck or shoulder pain in last month	3.8	5.4	8.5	-0.0	-0.0	-0.4	-2.4	-2.9	-2.7	-2.9	-2.6	-2.8	-2.8	-2.7
Medication: Bendroflumethiazide	3.7	5.6	10.1	1.1	2.0	0.5	1.8	1.6	2.8	3.2	2.9	2.4	3.2	2.8
HDL Cholesterol	3.6	6.0	12.2	-0.2	0.4	-2.7	1.9	2.3	2.4	2.3	3.4	2.8	2.6	3.5
Knee pain experienced in last month	3.5	5.4	8.9	-1.0	-2.0	-2.2	-1.7	-2.6	-2.1	-3.0	-2.5	-2.7	-2.6	-2.6
Had other major operations	3.4	4.2	6.9	-0.5	-0.3	-2.6	-0.8	-2.3	-2.1	-2.6	-2.4	-2.0	-2.5	-2.4
High blood pressure (mother)	3.3	4.7	9.7	1.8	1.0	0.7	0.1	1.7	1.8	3.1	3.0	2.0	3.1	2.9
Medication for pain relief, constipation, heartburn	3.1	5.3	11.2	1.2	0.4	0.3	1.4	2.3	2.0	3.4	3.0	2.5	3.0	3.0
Mouth/teeth dental problems: Bleeding gums	3.0	3.9	6.3	-2.5	-0.1	-2.3	0.3	-1.7	-1.8	-2.0	-2.4	-1.8	-2.4	-2.4
Fasting Glucose	2.9	3.5	6.3	0.3	-1.2	1.1	-1.7	-2.3	-2.0	-1.3	-2.5	-2.4	-1.8	-2.5
Osteoporosis (self-reported)	2.9	3.6	8.7	0.3	0.3	0.5	-2.5	-3.0	-2.0	-1.8	-2.1	-2.3	-1.7	-2.1
Reaction Time	2.8	5.2	8.6	2.5	2.2	1.8	-0.1	1.7	2.6	2.9	2.5	2.1	2.9	2.4
Mean time to correctly identify matches	2.8	5.3	7.6	1.2	2.5	1.9	0.9	2.2	2.7	2.8	2.6	2.6	2.6	2.6
Alcohol drinker status: Previous	2.8	3.2	6.4	0.4	1.4	1.8	1.6	2.5	1.9	1.8	1.8	2.2	1.4	1.9
Average weekly fortified wine intake	2.5	3.0	4.8	2.0	1.6	1.8	-0.0	1.1	1.8	2.1	1.8	1.5	2.2	1.8
Impedance of arm (right)	2.5	11.6	104.0	-0.5	-3.1	-10.2	-0.2	-2.3	-1.8	-1.3	-0.5	-1.5	-1.1	-0.5
Heart attack	2.3	3.0	5.4	0.1	-0.0	0.3	-1.2	-1.9	-1.7	-2.2	-2.3	-1.8	-2.3	-2.3
Hip circumference	2.3	10.0	94.1	-1.4	-1.0	-9.7	3.4	-0.2	0.1	0.1	0.8	0.0	0.4	0.8
Illnesses of mother	2.3	2.9	6.8	-2.0	-0.7	-2.0	0.3	-1.0	-1.3	-2.6	-1.8	-1.2	-2.4	-1.8
Impedance of arm (left)	2.3	10.6	102.0	-0.0	-2.7	-10.1	0.4	-1.9	-1.2	-0.9	-0.1	-1.0	-0.7	-0.1
Chronic bronchitis/emphysema (father)	2.2	2.6	4.5	0.2	-0.8	-0.4	2.1	2.1	2.0	1.5	1.7	2.0	1.5	1.7
Length of working week for main job	2.2	2.4	4.9	-2.0	0.4	-1.7	2.2	1.9	1.1	1.5	1.3	1.5	1.2	1.4
Heart attack/myocardial infarction (self-reported)	2.1	2.7	4.7	0.5	-0.0	0.5	-1.4	-1.9	-1.5	-2.1	-2.2	-1.7	-2.1	-2.2
Trunk fat percentage	2.0	8.1	80.9	-0.7	-1.3	-9.0	1.6	-1.5	-0.4	-0.1	0.4	-0.6	0.1	0.4
Crohns Disease (2012)	1.9	3.1	17.5	-4.2	-0.6	-2.7	0.9	-0.6	-1.1	-1.4	-0.9	-0.8	-1.4	-0.9
Ever had hysterectomy (womb removed)	1.9	2.2	6.2	-0.1	0.0	-0.1	-0.9	-1.9	-2.5	-1.7	-1.4	-2.0	-1.7	-1.4
Hair/balding pattern: Pattern 2	1.9	2.4	6.1	0.5	2.4	1.1	0.5	1.5	1.4	2.5	1.1	1.1	2.3	1.1
Medication: Paracetamol	1.9	3.0	5.0	-1.7	-2.2	-2.0	-0.4	-1.4	-1.1	-2.1	-1.9	-1.7	-1.8	-1.9
Alcohol drinker status: Never	1.9	2.3	3.9	-0.8	0.2	-0.1	-1.1	-1.7	-2.0	-1.8	-1.8	-1.9	-1.7	-1.8
Triglycerides	1.8	3.0	6.7	0.5	-0.0	2.6	-2.3	-1.7	-1.3	-1.5	-2.1	-1.8	-1.4	-2.1
Height	1.8	35.0	79.0	-5.9	0.4	-7.0	8.9	7.7	5.1	5.3	4.9	6.1	4.6	5.0
Eye problems/disorders: None of the above	1.8	2.1	7.0	-1.9	-0.7	-2.6	1.5	1.7	0.8	0.6	1.4	1.2	0.7	1.4
Medication: Aspirin	1.8	2.4	5.0	0.3	1.4	2.2	-1.8	-1.5	-1.4	-1.5	-1.6	-1.4	-1.5	-1.6
Ever had stillbirth, spontaneous miscarriage or termination	1.8	1.9	4.6	-1.0	-2.1	-1.1	0.2	-1.3	-1.2	-1.7	-1.5	-1.4	-1.5	-1.5
Pain type(s) experienced in last month: Hip pain	1.8	2.2	4.3	0.1	-0.7	-2.0	-1.0	-1.6	-0.7	-2.1	-1.8	-1.6	-1.5	-1.8
Relative age voice broke	1.7	2.7	5.9	0.5	-0.3	0.5	1.1	1.6	1.6	1.8	2.4	2.0	1.9	2.4
Osteoarthritis (self-reported)	1.7	2.2	7.5	0.3	-1.5	-2.7	-0.3	-1.1	0.1	-1.7	-1.8	-1.1	-1.4	-1.9
Wears glasses or contact lenses	1.7	2.0	11.0	-3.3	0.9	-0.7	1.8	0.8	-0.8	-1.1	-1.0	-0.2	-1.4	-1.0
Heel T-Score	1.6	12.9	60.8	-7.8	2.0	-2.9	4.5	5.3	1.4	1.6	1.7	2.9	0.9	1.8
Systolic Blood Pressure	1.6	7.8	21.5	2.3	1.7	4.6	-0.5	2.0	3.3	3.2	2.6	2.2	3.4	2.6
Had menopause	1.6	2.0	3.8	-0.2	1.1	-1.8	0.5	0.9	1.2	1.8	2.0	1.4	1.7	1.9
Shortness of breath walking on level ground	1.6	1.9	6.1	-0.3	2.5	-0.8	1.0	0.9	1.0	1.6	1.7	1.1	1.4	1.6
Leg pain on walking	1.6	2.0	6.8	-0.7	-0.4	-2.6	-0.8	-1.7	-0.7	-1.7	-1.4	-1.4	-1.3	-1.4
Worry (Nagel 2018)	1.5	3.2	7.2	-0.0	0.3	0.5	-2.7	-2.3	-2.1	-1.7	-1.9	-2.3	-1.6	-2.0
Diverticular disease/diverticulitis (self-reported)	1.5	1.7	6.0	1.8	-0.5	2.4	-2.4	-1.1	-0.7	-0.9	-0.6	-0.7	-0.7	-0.6
Falls in the last year	1.5	2.0	16.6	-1.2	-0.6	-4.1	1.1	-0.5	-0.4	-0.7	-0.5	-0.6	-0.5	-0.5
Glaucoma (self-reported)	1.5	1.8	5.0	0.8	0.4	-0.7	-1.5	-2.2	-1.0	-0.8	-1.7	-1.5	-1.1	-1.7
Medication: Amlodipine	1.5	2.1	3.4	0.9	1.8	1.7	0.5	1.3	1.2	1.7	1.6	1.4	1.6	1.6
Body fat percentage	1.5	6.0	60.2	-0.1	-1.0	-7.8	1.0	-1.8	-0.4	-0.3	0.2	-0.9	0.1	0.1
Migraine (self-reported)	1.5	1.8	4.4	-2.1	0.4	-2.0	0.2	-0.3	-1.3	-1.4	-1.5	-1.0	-1.6	-1.5
Medication: Aspirin	1.5	1.9	5.6	0.3	1.5	2.4	-1.4	-1.1	-1.2	-1.3	-1.4	-1.1	-1.4	-1.4
Financial situation satisfaction	1.5	1.9	5.8	0.1	2.4	-1.2	1.5	1.4	1.3	1.3	1.2	1.3	1.2	1.2
Medication: Atorvastatin	1.5	1.8	3.6	-0.3	1.7	1.9	-1.7	-1.5	-1.2	-1.0	-1.2	-1.4	-0.9	-1.2
Impedance of whole body	1.5	7.9	59.0	0.7	-2.9	-7.7	-1.6	-2.7	-1.8	-1.0	-0.5	-1.7	-0.8	-0.5
Alzheimer’s Disease (in mother)	1.4	1.6	7.5	-1.9	-1.3	-1.4	2.7	1.2	1.0	0.2	0.0	0.9	-0.0	0.0
Hand grip strength (left)	1.4	3.6	8.9	0.7	0.0	2.3	-3.0	-1.9	-1.5	-1.7	-2.2	-2.3	-1.1	-2.2
Trunk fat mass	1.4	6.2	57.6	-1.4	-0.7	-7.6	2.4	-0.3	0.2	0.4	0.8	0.1	0.6	0.7
Alcohol intake frequency.	1.4	3.3	5.6	-1.7	0.9	-0.2	-0.9	-1.4	-2.3	-2.1	-2.4	-2.0	-2.4	-2.3
Supplements: Vitamin C	1.4	1.6	3.4	-0.8	-0.8	-0.8	-0.3	-1.0	-0.8	-1.7	-1.8	-1.1	-1.7	-1.8
Medication for cholesterol	1.4	2.2	6.3	-1.9	-1.0	-2.5	0.1	-0.3	-1.7	-1.7	-1.3	-1.0	-1.8	-1.2
Father’s age at death	1.3	1.8	4.0	-0.4	0.2	-0.7	-1.1	-1.5	-2.0	-1.7	-1.3	-1.4	-1.8	-1.4
Prospective memory result	1.3	1.7	4.5	1.5	1.3	2.1	0.4	0.8	1.2	1.5	1.0	1.2	1.2	1.0
Medication: Paracetamol	1.3	2.1	5.2	-2.3	-1.4	-2.0	0.5	-0.9	-0.7	-1.8	-1.4	-1.2	-1.4	-1.4
Birth weight	1.3	2.7	12.0	-1.6	-0.7	-2.1	3.5	1.9	1.6	0.3	1.1	1.4	0.8	1.1
Worry too long after embarrassment	1.3	2.1	4.2	-0.5	0.1	-0.0	-1.9	-2.1	-1.7	-1.3	-1.6	-2.0	-1.4	-1.6
Suffer from ‘nerves’	1.3	2.1	3.8	0.6	0.2	1.0	-2.0	-1.6	-1.2	-1.7	-1.7	-1.8	-1.4	-1.7
Commuting to job workplace: Public transport	1.3	1.5	4.1	2.0	1.0	1.5	0.1	0.5	1.2	1.6	1.0	0.8	1.6	1.0
Alzheimer’s Disease (in father)	1.2	1.3	1.9	-1.3	-0.3	-1.0	-0.8	-1.4	-1.0	-1.0	-1.4	-1.2	-1.1	-1.3
Alzheimer’s Disease (including proxy)	1.2	1.7	7.7	-2.8	-1.0	-2.1	2.2	0.6	0.7	-0.1	-0.2	0.5	-0.2	-0.2
Lung FEV1/FVC ratio	1.2	6.3	24.7	-5.0	-0.7	0.7	-2.6	-0.3	-3.8	-1.7	-1.9	-1.4	-3.2	-1.9
Arm fat percentage (right)	1.2	4.9	48.6	-0.6	-0.4	-7.0	1.8	-0.9	0.0	-0.3	0.4	-0.3	0.0	0.3
Medication: Cholesterol lowering	1.2	1.9	3.5	-0.9	0.7	1.2	-1.6	-1.5	-1.9	-1.1	-1.5	-1.7	-1.3	-1.5
Exposure to tobacco smoke at home	1.2	1.3	2.6	0.4	0.7	1.4	-1.5	-1.4	-1.3	-0.7	-1.1	-1.6	-0.6	-1.1
Arm fat percentage (left)	1.2	4.8	47.5	-0.4	-0.4	-6.9	1.9	-0.8	0.2	-0.1	0.6	-0.1	0.3	0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.2	2.5	5.2	-1.1	-0.4	-0.8	-1.0	-2.1	-2.3	-1.8	-1.6	-1.9	-1.8	-1.6
Major Depression (MDD)	1.1	1.3	5.4	-1.1	-1.0	-2.3	1.5	-0.1	0.0	-1.2	-0.9	-0.4	-1.0	-0.9
Rheumatoid Arthritis	1.1	1.6	5.9	-0.4	-0.1	-0.2	-0.8	-1.2	-2.4	-1.0	-1.3	-1.6	-1.5	-1.3
Medication: Metformin	1.1	1.6	12.2	-0.3	1.2	3.5	1.0	0.5	0.4	-0.5	-1.0	0.1	-0.7	-0.9
Hand grip strength (right)	1.1	3.0	6.2	0.1	-0.0	2.5	-2.2	-1.6	-1.7	-1.7	-2.0	-2.0	-1.4	-2.0
Mouth/teeth dental problems	1.1	1.6	3.5	-0.1	-0.0	1.7	0.7	1.4	0.8	1.2	1.9	1.4	1.3	1.8
Pain all over the body in last month	1.1	1.2	2.9	1.3	0.1	-1.3	-0.0	0.9	1.1	1.5	1.1	0.6	1.7	1.1
Time employed in main current job	1.1	1.3	5.3	-1.5	-1.6	-2.3	1.8	0.4	0.0	-0.6	-0.2	0.3	-0.6	-0.1
Serious illness, injury or assault of a close relative in last 2 years	1.1	1.3	8.0	-2.8	-0.3	-0.5	0.9	-0.0	-0.9	-0.7	-1.0	-0.6	-1.1	-1.0
Pulse wave reflection index	1.1	1.3	3.3	0.9	-0.5	1.7	0.9	1.2	1.8	0.8	0.9	1.4	0.9	0.8
Blood clot in the leg (DVT)	1.1	1.5	2.6	-0.1	-0.9	-0.4	-0.8	-1.3	-1.2	-1.5	-1.6	-1.4	-1.5	-1.6
Arm fat-free mass (right)	1.1	5.5	11.2	-2.0	1.8	2.4	2.9	3.4	2.2	2.3	1.9	2.4	2.1	2.0
Leg fat-free mass (right)	1.1	5.9	18.8	-3.5	1.0	-1.6	4.3	3.4	1.6	1.6	1.8	2.2	1.5	1.8
Leg predicted mass (right)	1.1	5.6	18.7	-3.5	0.9	-1.6	4.3	3.3	1.5	1.5	1.6	2.1	1.3	1.7
Number of operations (self-reported)	1.1	1.7	3.9	-0.2	-0.5	-0.6	-1.1	-1.1	-1.4	-2.0	-1.5	-1.2	-1.9	-1.5
Tinnitus: Yes, but not now, but have in the past	1.0	1.1	3.5	1.1	-1.9	-0.3	-0.5	-1.1	-0.3	-1.2	-1.0	-0.9	-1.0	-1.1
Hayfever/allergic rhinitis (self-reported)	1.0	1.3	5.5	1.1	-0.4	2.3	-1.2	-1.1	-1.3	-0.9	-0.6	-0.8	-1.0	-0.6
Trunk fat-free mass	1.0	6.0	15.0	-2.7	1.7	2.5	3.4	3.9	2.2	2.0	1.6	2.5	1.8	1.6
Depression (self-reported)	1.0	1.2	2.6	1.5	0.3	-0.1	-1.6	-1.3	-0.8	-1.4	-1.0	-1.2	-1.0	-1.0
Medication: Lansoprazole	1.0	1.1	1.8	0.7	0.4	1.4	0.2	1.1	1.0	1.2	1.3	1.1	1.1	1.3
Trunk predicted mass	1.0	5.7	14.1	-2.7	1.8	2.4	3.4	3.8	2.1	1.9	1.5	2.3	1.7	1.5
Whole body fat mass	1.0	4.2	40.0	-1.0	-0.4	-6.3	1.9	-0.4	0.3	0.3	0.6	-0.0	0.6	0.6
Arm predicted mass (right)	1.0	5.0	10.6	-2.1	1.6	2.4	2.8	3.3	2.1	2.1	1.8	2.3	2.0	1.8
Number of full sisters	1.0	1.2	1.9	1.1	1.0	-0.9	0.6	1.0	1.3	1.3	1.2	0.9	1.4	1.1
Whole body fat-free mass	1.0	5.5	13.5	-3.0	1.5	0.9	3.7	3.6	2.0	1.8	1.6	2.3	1.7	1.7
High cholesterol (Self-reported)	1.0	1.8	2.7	-0.2	0.6	1.5	-1.1	-1.6	-1.6	-1.2	-1.5	-1.6	-1.3	-1.5
Primary Biliary Cirrhosis	0.9	1.3	6.7	-1.1	1.8	-0.6	2.6	0.9	0.6	0.4	0.5	0.6	0.3	0.5
Sensitivity / hurt feelings	0.9	1.5	3.0	-1.1	0.1	-0.6	1.7	1.7	1.4	0.6	1.4	1.7	0.6	1.4
Systolic blood pressure, automated reading	0.9	2.6	11.6	1.5	1.1	3.4	-0.8	0.3	1.4	2.0	1.1	0.7	2.0	1.1
Leg fat-free mass (left)	0.9	4.9	14.5	-3.1	1.0	-2.0	3.8	3.0	1.6	1.5	1.6	1.9	1.5	1.6
Leg predicted mass (left)	0.9	4.9	14.3	-3.0	1.1	-1.9	3.8	3.0	1.6	1.5	1.6	1.9	1.5	1.7
Number of incorrect matches in round	0.9	1.6	3.3	-0.8	0.1	-0.7	1.8	1.5	1.3	1.1	1.5	1.4	1.2	1.5
Ever unenthusiastic/disinterested for a whole week	0.9	1.1	2.2	-0.7	-0.4	-1.1	0.3	-1.0	-1.1	-1.4	-1.2	-0.9	-1.5	-1.3
Arm fat mass (right)	0.9	3.6	29.0	-1.4	0.1	-5.4	2.6	0.3	0.6	0.4	0.9	0.5	0.5	0.9
Standing height	0.9	9.4	19.2	-4.3	-0.7	-4.4	4.4	3.9	1.6	2.5	2.4	2.6	2.1	2.5
High blood pressure (siblings)	0.9	1.2	5.5	1.1	1.2	2.4	-0.9	0.4	1.1	1.1	0.6	0.6	1.0	0.6
Family relationship satisfaction	0.9	1.1	5.9	-1.1	-0.1	-2.4	1.3	-0.4	-1.2	-0.6	-0.3	-0.6	-0.7	-0.3
Forced expiratory volume in 1-second (FEV1), predicted	0.9	1.8	4.1	-1.2	0.3	-1.5	1.9	2.0	0.6	1.4	1.2	1.2	1.3	1.2
Commuting to job workplace: Walk	0.9	1.0	4.5	2.1	0.6	0.5	0.3	0.5	0.5	0.9	1.1	0.9	0.8	1.1
Whole body water mass	0.9	5.4	13.2	-3.0	1.5	1.0	3.6	3.6	2.0	1.8	1.6	2.3	1.7	1.7
Tinnitus: Yes, now most or all of the time	0.9	1.1	5.9	1.4	2.4	0.7	-0.6	0.3	0.1	1.1	0.8	0.5	0.7	0.8
Eye problems/disorders: Glaucoma	0.9	1.1	3.2	0.8	0.9	-0.6	-1.0	-1.8	-0.6	-0.6	-1.2	-1.1	-0.7	-1.2
Medication: Blood pressure	0.9	1.8	4.8	2.2	1.0	1.6	0.1	-0.3	1.3	1.6	1.3	0.6	1.8	1.3
Cholesterol lowering medication	0.9	1.4	4.5	2.1	2.0	1.9	-1.2	-0.8	-0.1	0.3	-0.1	-0.4	0.3	-0.1
Blood White Count	0.8	5.9	18.3	2.4	1.0	4.3	-3.5	-2.5	-2.5	-1.2	-1.7	-2.5	-1.1	-1.7
Respiratory disease	0.8	1.8	7.0	-0.1	1.2	2.6	0.9	1.3	0.6	1.5	1.3	0.9	1.4	1.3
Medication for hormone replacement therapy	0.8	0.9	1.6	-0.7	-0.4	0.4	-0.2	1.2	1.2	0.8	1.2	1.3	0.9	1.2
Supplements: Zinc	0.8	0.8	2.1	-1.3	0.2	0.3	0.8	-0.2	-1.1	-1.4	-0.7	-0.5	-1.5	-0.8
Heel bone mineral density (BMD) T-score, automated (left)	0.8	1.9	9.9	-3.1	1.0	-1.0	1.5	1.9	0.3	0.9	0.7	1.0	0.6	0.7
Impedance of leg (left)	0.8	3.8	10.3	1.9	-2.7	-3.2	-2.8	-2.6	-1.4	-0.6	-0.6	-1.6	-0.5	-0.7
Illnesses of siblings	0.8	1.1	3.2	-0.5	-1.3	-1.5	-0.5	-0.9	-1.8	-0.8	-0.7	-1.0	-0.9	-0.6
Weight	0.8	4.1	18.8	-2.2	0.3	-4.3	3.4	1.5	1.1	1.0	1.3	1.2	1.1	1.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.8	2.6	5.9	-2.4	-1.3	-2.4	-0.1	-0.9	-2.0	-1.6	-1.4	-1.4	-1.7	-1.3
Tense / ‘highly strung’	0.8	1.3	6.2	0.9	1.0	2.1	-2.5	-0.7	-0.2	-0.2	-0.3	-0.9	0.3	-0.3
Medication: Blood pressure	0.8	1.4	5.8	-0.7	2.4	0.6	0.2	0.9	1.3	1.3	1.0	0.9	1.3	1.0
Long-standing illness, disability or infirmity	0.8	1.2	4.2	-2.0	1.3	-1.9	0.7	0.0	-0.7	-0.7	-0.7	-0.4	-0.8	-0.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	0.9	1.6	-0.6	0.3	-0.4	1.0	-1.1	-1.2	-0.9	-1.1	-1.0	-1.3	-1.1
Arm fat mass (left)	0.8	3.4	26.5	-1.1	0.2	-5.1	2.5	0.5	0.8	0.5	1.0	0.6	0.7	1.0
Average weekly champagne plus white wine intake	0.8	1.1	2.4	-1.3	0.3	-0.0	1.1	1.6	0.9	1.1	1.1	1.4	0.8	1.1
Mother’s age at death	0.8	1.0	2.7	-1.6	1.4	-1.6	0.5	-0.2	-0.9	-0.8	-0.8	-0.6	-1.0	-0.8
Illnesses of father: High blood pressure	0.8	0.9	3.0	1.7	1.1	1.7	-0.2	0.2	0.4	0.6	0.9	0.5	0.8	0.9
Basal metabolic rate	0.8	4.7	13.2	-2.7	1.3	-0.5	3.6	3.2	1.9	1.7	1.6	2.1	1.7	1.7
Commuting to job workplace: Cycle	0.8	1.0	1.7	1.2	0.3	-0.7	-1.0	-0.7	-0.6	-1.3	-1.2	-0.8	-1.2	-1.2
Myopia	0.8	1.2	2.8	-1.7	-1.5	-0.1	1.1	0.1	-0.9	-1.4	-0.9	-0.3	-1.4	-0.8
Heart disease (siblings)	0.8	0.9	3.3	-1.8	1.3	-1.6	0.7	-0.4	-0.6	-0.8	-0.2	-0.2	-0.8	-0.2
Schizophrenia vs Biploar Disorder	0.7	0.9	6.3	-0.4	0.1	-2.5	1.5	0.4	0.7	-0.2	0.0	0.4	-0.1	-0.0
Mean Putamen Volume	0.7	0.8	4.0	-0.6	-0.8	-2.0	-0.4	-0.4	-0.4	-1.2	-0.6	-0.5	-0.9	-0.6
Lupus	0.7	1.0	7.1	0.1	2.7	0.0	-0.9	0.3	0.4	0.6	0.9	0.6	0.7	0.8
Impedance of leg (right)	0.7	3.5	10.1	2.2	-2.0	-3.0	-3.2	-2.5	-1.0	-0.4	-0.6	-1.5	-0.2	-0.6
Townsend deprivation index at recruitment	0.7	0.9	2.0	0.4	0.5	-0.6	1.0	1.0	0.5	1.4	1.1	0.9	1.3	1.1
Taking other prescription medications	0.7	1.0	2.2	1.0	0.9	0.3	0.5	0.9	1.5	0.9	1.1	1.1	1.3	1.1
Waist circumference	0.7	2.6	5.2	-0.0	1.9	-0.8	2.3	1.6	1.7	2.0	1.5	1.5	1.9	1.5
Heel bone mineral density (BMD) T-score, automated (right)	0.7	1.6	6.8	-2.6	1.1	-1.1	1.0	1.9	0.6	0.9	0.7	0.9	0.7	0.7
Diabetes (self-reported)	0.7	1.1	7.5	-0.6	1.9	2.7	0.6	0.1	0.1	-0.1	-0.5	0.2	-0.5	-0.5
Forced expiratory volume in 1-second (FEV1)	0.7	2.3	7.4	-2.7	-1.3	-2.3	0.5	-0.3	-1.7	-1.6	-1.1	-0.9	-1.7	-1.0
Birth weight of first child	0.7	1.3	4.5	-2.1	-1.2	-1.9	1.6	0.7	-0.5	-0.5	-0.4	0.1	-0.9	-0.4
Number of full brothers	0.7	0.8	2.3	0.1	1.5	-1.4	1.5	0.8	1.2	0.4	0.1	0.5	0.5	0.1
Illness, injury, bereavement, stress in last 2 years	0.7	0.8	1.5	0.8	-0.3	1.0	-0.0	0.9	0.6	1.0	1.2	0.8	1.1	1.2
Illnesses of father: Heart disease	0.7	0.9	3.4	1.8	0.9	1.3	-1.8	-0.6	-0.6	0.5	-0.1	-0.5	0.4	-0.1
Smoking status: Previous	0.7	1.1	2.5	0.4	1.4	-0.6	1.1	0.7	1.5	1.6	0.7	0.9	1.2	0.7
Diabetes diagnosed by doctor	0.7	1.2	10.7	0.1	1.1	3.3	0.2	-0.2	0.2	-0.1	-0.5	0.1	-0.5	-0.6
Friendships satisfaction	0.7	0.8	2.5	-0.5	0.8	-1.3	-0.1	-0.9	-1.6	-0.5	-0.8	-1.1	-0.9	-0.8
Illnesses of father: None of the above (group 1)	0.7	0.8	2.9	-1.0	-1.7	-1.0	-0.4	-0.6	-1.1	-0.7	-0.7	-0.7	-0.8	-0.6
Leg fat percentage (left)	0.7	2.6	19.1	1.1	-1.1	-4.4	-0.0	-2.2	-0.5	-0.5	-0.4	-1.2	-0.2	-0.5
Arm fat-free mass (left)	0.7	3.6	7.7	-2.1	1.7	2.0	2.1	2.8	1.7	1.8	1.3	1.7	1.7	1.4
Average weekly beer plus cider intake	0.7	1.0	3.6	1.9	1.3	1.7	-1.4	-0.3	0.2	0.4	0.2	-0.1	0.5	0.2
Ever depressed for a whole week	0.7	0.9	1.9	-0.9	1.1	-0.6	1.4	1.4	1.3	0.4	0.5	1.1	0.5	0.5
Unable to work because of sickness or disability	0.7	0.9	2.4	0.7	0.5	-1.3	1.6	0.7	1.4	0.5	0.8	0.9	0.7	0.8
Deep venous thrombosis (DVT) (self-reported)	0.7	0.9	1.6	0.3	-0.5	-0.1	-0.6	-1.0	-0.9	-1.1	-1.2	-1.1	-1.1	-1.3
Arm predicted mass (left)	0.7	3.4	7.6	-2.3	1.5	1.9	2.2	2.8	1.6	1.6	1.3	1.7	1.5	1.4
Ulcerative Colitis	0.6	0.8	5.1	-0.6	0.1	-2.3	0.7	-0.7	-0.2	-0.2	-1.0	-0.7	-0.3	-1.0
Type 2 Diabetes (T2D) (2018)	0.6	1.2	7.0	0.1	2.3	2.6	0.4	-0.1	0.3	0.3	-0.5	0.1	-0.1	-0.5
Other serious medical condition/disability diagnosed by doctor	0.6	0.8	3.4	-1.9	-0.1	-0.7	0.5	-0.6	-0.9	-1.0	-0.8	-0.6	-1.1	-0.8
Angina	0.6	0.8	2.6	1.2	1.6	0.8	-1.2	-0.7	-0.8	-0.6	-0.7	-0.8	-0.5	-0.6
Current tobacco smoking	0.6	0.9	3.3	-1.8	1.0	-1.8	1.5	0.4	-0.2	-0.5	0.3	0.1	-0.3	0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.8	3.9	2.0	1.0	0.9	-1.1	-0.1	0.1	0.8	0.4	-0.0	0.7	0.4
Qualifications: CSEs or equivalent	0.6	0.8	2.8	-0.4	1.7	-0.5	-0.2	1.1	0.9	0.8	0.9	0.8	0.9	0.9
Alcohol usually taken with meals	0.6	1.0	5.8	-0.1	-0.4	2.4	-0.9	-0.5	-1.1	-0.4	-0.8	-0.6	-0.8	-0.8
Allergy	0.6	1.3	6.8	-1.9	-0.5	-2.6	1.2	-0.5	0.2	-0.5	-0.7	-0.3	-0.5	-0.8
Happiness	0.6	0.8	2.6	0.1	1.6	-1.6	1.0	0.8	0.9	0.4	0.3	0.4	0.5	0.3
Leg fat percentage (right)	0.6	2.4	19.2	1.3	-0.4	-4.4	-0.1	-2.0	0.0	-0.1	-0.1	-0.9	0.2	-0.2
Exposure to tobacco smoke outside home	0.6	0.8	3.3	-1.1	1.8	-1.5	1.1	0.5	0.3	0.1	0.4	0.2	0.3	0.4
Angina (self-reported)	0.6	0.8	2.4	1.5	1.5	1.1	-1.1	-0.5	-0.5	-0.4	-0.5	-0.5	-0.3	-0.5
Heart disease (mother)	0.6	0.8	2.3	0.7	-1.1	1.5	-1.3	-0.9	-0.9	-0.1	-0.2	-0.8	-0.1	-0.2
Eye problems/disorders: Cataract	0.6	0.7	5.9	0.8	0.3	2.4	0.4	0.2	0.3	0.7	0.1	0.3	0.4	0.1
Medication: Gliclazide	0.6	0.7	4.8	0.9	0.3	2.2	-0.5	-0.0	0.8	0.4	0.1	0.3	0.5	0.1
Smoking status: Current	0.6	1.0	3.8	-1.9	0.8	-1.9	1.5	0.5	-0.2	-0.5	0.3	0.1	-0.3	0.2
Hearing aid user	0.6	0.6	3.0	0.4	1.7	-0.8	0.0	0.0	0.6	1.0	0.5	0.4	1.0	0.5
Medication: Lisinopril	0.6	0.8	3.1	1.4	1.8	0.3	0.3	-0.0	1.3	0.8	0.3	0.3	0.9	0.2
Depression (Nagel 2018)	0.5	0.7	4.0	2.0	0.8	0.7	-1.1	-0.3	0.1	0.9	0.2	-0.2	0.7	0.2
Ovarian Cancer	0.5	0.6	1.1	1.0	0.8	-0.1	0.2	0.5	0.6	0.9	1.0	0.8	1.0	1.0
Age at First Birth	0.5	0.7	3.2	-1.4	0.0	-1.8	1.3	1.0	0.3	0.1	-0.1	0.4	0.0	0.1
Body Mass Index (BMI) (2010)	0.5	0.6	3.5	-0.1	1.9	-0.9	1.1	0.1	0.9	0.1	0.4	0.6	0.2	0.4
Cardiovascular Disease	0.5	1.7	5.2	1.1	2.3	1.8	-0.9	-0.0	1.0	1.4	1.0	0.3	1.6	0.9
Hypothyroidism (self reported)	0.5	1.2	4.5	-1.3	0.5	-2.1	0.2	-0.9	-1.0	-0.7	-1.2	-1.1	-0.8	-1.2
Diabetes (father)	0.5	0.6	3.4	-0.5	1.9	0.6	1.3	0.4	0.2	-0.4	-0.4	0.5	-0.8	-0.4
Maternal smoking around birth	0.5	0.8	1.8	0.9	1.3	1.1	0.4	0.6	1.0	1.2	0.5	0.6	1.0	0.5
Bilateral oophorectomy (both ovaries removed)	0.5	0.5	1.9	0.5	1.4	0.1	-0.0	0.6	0.3	0.3	1.1	0.7	0.6	1.1
High blood pressure	0.5	1.5	3.2	1.1	1.3	1.4	-0.0	0.2	1.8	1.6	1.0	0.7	1.8	1.0
Supplements: Glucosamine	0.5	0.7	3.1	-0.9	-1.8	-1.0	0.2	0.0	0.6	-1.2	-0.5	0.0	-0.7	-0.5
Medication: Atenolol	0.5	0.6	1.9	-1.4	0.4	-0.8	-0.7	-0.8	-0.8	-0.7	-0.6	-1.0	-0.6	-0.6
Medication: Levothyroxine sodium	0.5	0.9	3.6	-1.4	-0.7	-0.9	1.9	0.5	0.5	0.7	0.7	0.7	0.5	0.7
Sitting height	0.5	3.3	12.5	-3.5	-0.3	-2.0	1.9	2.3	0.6	1.8	1.2	0.8	1.7	1.3
Medication: Simvastatin	0.5	0.7	1.4	0.3	1.1	0.6	-0.8	-1.1	-0.9	-0.4	-1.0	-1.2	-0.4	-1.0
Pulse rate	0.5	0.8	2.4	-0.8	-0.3	-0.1	-1.0	-1.2	-1.5	-0.8	-0.7	-0.9	-1.0	-0.7
Noisy workplace	0.5	0.6	3.3	0.0	1.8	0.3	0.5	-0.8	0.7	0.2	-0.7	-0.3	0.1	-0.8
Asthma	0.5	1.0	2.3	-0.1	0.9	1.5	0.2	1.1	0.7	1.2	1.0	0.8	1.2	1.0
Peak expiratory flow (PEF)	0.5	1.3	6.0	-2.5	-1.2	-0.9	-0.4	0.1	-0.7	-1.4	-0.8	-0.5	-1.3	-0.8
Hypothyroidism/myxoedema (self-reported)	0.5	0.9	3.4	-1.6	-0.8	-1.8	1.1	-0.3	-0.9	-0.5	-0.6	-0.5	-0.7	-0.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.7	1.0	0.5	0.6	0.4	-0.9	-1.0	-0.9	-1.0	-0.8	-0.9	-1.0	-0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	1.4	-0.4	0.0	-0.7	-0.9	-1.0	-1.0	-0.8	-0.6	-1.2	-0.5	-0.6
Leg fat mass (right)	0.5	2.1	19.0	-0.1	0.2	-4.4	1.0	-0.5	0.6	0.5	0.7	0.0	0.9	0.6
Overall health rating	0.5	1.0	3.7	0.3	-0.5	-1.9	-0.8	-1.2	-0.4	-1.4	-0.8	-1.0	-0.8	-0.8
Ever had bowel cancer screening	0.5	0.5	1.5	0.5	0.5	0.6	1.1	0.6	1.2	0.1	0.7	0.9	0.5	0.6
Qualifications: nursing, teaching	0.5	0.7	2.1	0.4	-1.4	0.8	-0.8	-0.4	-0.6	-0.9	-0.9	-0.4	-1.0	-0.9
Asthma (self-reported)	0.5	1.1	2.4	-0.1	0.8	1.6	0.3	1.2	0.7	1.4	1.1	0.9	1.4	1.1
Miserableness	0.5	0.9	2.3	1.5	0.9	-0.6	-1.3	-1.1	-0.7	-0.6	-0.9	-1.0	-0.5	-0.9
Guilty feelings	0.5	0.8	2.6	1.6	-0.4	1.2	-1.6	-0.7	-0.1	0.6	0.5	-0.3	0.8	0.5
Ever taken oral contraceptive pill	0.5	0.6	1.8	0.2	-1.3	0.2	0.3	1.1	1.4	0.2	0.3	0.9	0.5	0.3
Diastolic blood pressure, automated reading	0.5	1.5	4.8	2.2	0.7	-1.5	-1.4	-1.9	0.1	0.9	-0.1	-1.0	1.2	-0.1
Vascular/heart problems diagnosed by doctor	0.5	1.3	3.9	-1.3	-2.0	-1.7	0.1	0.1	-1.3	-1.2	-0.7	-0.5	-1.3	-0.6
Leg fat mass (left)	0.5	2.1	20.2	-0.3	-0.3	-4.5	1.2	-0.5	0.4	0.4	0.6	-0.0	0.6	0.5
Crohns Disease (2017)	0.4	0.8	7.7	-2.8	0.3	-0.5	0.7	-0.3	0.1	0.1	-0.3	-0.3	0.0	-0.3
Irritable Bowel Disease (IBD)	0.4	1.0	3.5	-1.8	0.4	-1.9	1.0	-0.8	-0.4	0.1	-0.8	-0.7	-0.2	-0.8
Ulcerative Colitis (UC)	0.4	0.8	5.8	-0.3	0.1	-2.4	1.2	-0.3	-0.3	0.4	-0.5	-0.4	0.0	-0.4
Verbal and Numeric Reasoning (VNR)	0.4	1.0	1.7	0.4	0.9	0.2	0.8	1.2	1.3	1.2	0.9	1.2	1.1	0.9
HbA1C	0.4	0.4	1.1	-0.3	0.2	-0.9	0.5	0.7	0.3	0.5	1.0	0.6	0.5	1.0
Neuroticism (2016)	0.4	0.6	3.6	-0.9	0.9	-1.9	0.7	0.7	0.1	0.3	0.4	0.6	0.1	0.4
Blood Platelet Count	0.4	4.8	20.9	4.6	1.8	3.4	-2.4	-0.8	0.2	2.0	1.4	0.3	1.8	1.4
Blood Red Count	0.4	4.2	14.9	0.6	0.9	3.6	-3.9	-1.7	-2.2	-0.0	-1.6	-2.1	-0.3	-1.5
Smoking Status	0.4	1.0	5.2	-0.6	2.3	-1.8	1.1	0.1	0.2	0.6	0.4	0.0	0.6	0.4
Number of treatments/medications taken	0.4	0.6	1.7	-0.7	0.1	-0.1	-0.9	-0.9	-0.3	-1.3	-0.9	-0.8	-0.9	-0.9
Average weekly spirits intake	0.4	0.5	2.5	-1.6	0.7	-0.9	0.8	0.2	0.5	-0.3	-0.5	0.2	-0.3	-0.5
Multivitamins +/- minerals	0.4	0.5	2.4	1.6	0.6	1.4	-0.5	-0.5	0.4	-0.2	0.2	0.1	0.1	0.2
Past tobacco smoking	0.4	0.8	2.6	0.5	-0.7	1.3	-1.6	-0.8	-1.0	-0.9	-0.6	-0.7	-0.6	-0.6
Forced vital capacity (FVC)	0.4	1.4	7.7	-1.7	-0.7	-2.8	1.5	0.1	-0.6	-0.8	-0.3	-0.3	-0.6	-0.3
Medication: Ramipril	0.4	0.5	3.0	0.0	1.1	1.7	-0.5	-0.1	0.4	0.5	0.2	0.0	0.5	0.2
Number of live births	0.4	0.6	2.6	-0.4	-1.6	-0.6	-0.4	-1.0	-0.8	-0.6	-0.4	-0.8	-0.5	-0.4
Ever highly irritable/argumentative for 2 days	0.4	0.5	3.7	-0.2	-0.6	-1.9	0.8	-0.3	0.1	-0.4	-0.1	-0.1	-0.2	-0.1
Qualifications: O levels/GCSEs or equivalent	0.4	0.7	1.6	0.0	1.1	0.1	0.6	1.1	0.2	1.3	0.9	0.9	0.9	0.9
Emphysema/chronic bronchitis	0.4	0.5	1.2	-0.0	0.2	1.1	-0.6	0.4	0.4	1.0	0.6	0.2	1.1	0.6
Comparative height size at age 10	0.4	2.2	12.0	-2.4	-1.4	-3.5	2.0	0.4	-0.5	0.2	0.2	0.2	-0.1	0.2
Hypertension (Self-reported)	0.4	1.2	2.9	0.9	1.3	1.0	-0.1	0.0	1.6	1.5	0.9	0.6	1.7	0.9
Average weekly red wine intake	0.4	0.6	2.1	-0.2	0.9	0.2	1.4	1.3	0.6	0.4	0.6	1.0	0.1	0.6
Back pain experienced in last month	0.4	0.6	1.7	-0.3	0.4	0.4	-1.1	-1.3	-0.4	-0.7	-0.9	-0.9	-0.4	-0.9
Breast cancer (self-reported)	0.4	0.5	1.7	-0.8	-0.8	1.3	1.0	0.4	0.1	-0.5	-0.5	0.1	-0.4	-0.5
Supplements: Fish oil (including cod liver oil)	0.4	0.5	1.4	0.1	-0.3	0.4	0.7	0.9	1.2	0.2	0.8	1.1	0.4	0.8
Irritability	0.4	0.7	1.2	0.6	0.9	-0.9	0.5	0.8	1.1	0.9	0.9	0.8	1.0	0.9
Supplements: Calcium	0.4	0.4	0.8	-0.8	0.5	-0.4	0.8	0.6	0.7	0.4	0.7	0.9	0.5	0.7
Pack years of smoking	0.4	0.6	1.5	-1.0	0.1	0.2	0.3	0.2	-0.5	-1.0	-1.2	-0.6	-1.0	-1.2
Intelligence (Savage-Jansen 2018)	0.3	0.8	1.8	-0.5	0.5	0.3	1.3	1.2	1.3	0.9	0.5	1.2	0.8	0.6
Coronary Artery Disease (CAD)	0.3	0.4	2.7	0.8	0.2	1.6	-0.5	0.2	0.3	-0.0	0.5	0.2	0.4	0.4
Type 2 Diabetes (T2D) (2012)	0.3	0.4	3.2	-0.1	0.5	1.8	-0.6	0.0	-0.2	0.1	0.2	0.1	0.2	0.2
BMI	0.3	1.5	8.0	0.2	1.3	-2.8	1.8	-0.1	1.0	0.7	0.6	0.2	1.1	0.6
Allergy or Eczema	0.3	0.8	6.4	1.1	-1.0	2.5	-0.3	0.2	-0.6	-0.1	0.1	0.2	-0.4	0.1
Lung FVC	0.3	1.8	4.7	-0.9	-0.9	-2.2	1.2	-1.5	-0.7	-1.8	-1.1	-1.0	-1.4	-1.1
Frequency of depressed mood in last 2 weeks	0.3	0.4	1.4	1.1	0.7	1.2	-1.1	-0.2	-0.3	0.4	0.2	-0.0	0.1	0.2
Medication: Co-codamol	0.3	0.3	0.9	-1.0	0.4	0.8	-0.1	0.6	0.8	-0.1	0.3	0.5	0.2	0.3
Severe depression (siblings)	0.3	0.3	0.7	0.0	-0.8	-0.7	-0.3	-0.4	0.1	-0.6	-0.8	-0.6	-0.5	-0.8
Pack years adult smoking proportion	0.3	0.5	1.0	-1.0	0.5	0.0	0.4	0.3	-0.4	-0.9	-1.0	-0.4	-0.9	-1.0
Age when periods started (menarche)	0.3	0.6	1.8	0.0	0.7	-0.3	0.2	0.4	1.3	1.2	0.6	0.5	1.3	0.6
Serious illness, injury or assault to yourself	0.3	0.4	0.8	0.5	0.9	-0.8	0.3	-0.0	0.3	0.4	0.9	0.7	0.3	0.9
Hayfever, allergic rhinitis or eczema	0.3	0.6	3.6	1.3	0.2	1.9	-0.5	0.5	-0.4	0.1	0.5	0.4	-0.1	0.5
Nervous feelings	0.3	0.5	1.2	-1.1	0.7	-0.6	-0.4	-0.5	-0.8	-1.0	-0.1	-0.4	-0.9	-0.1
Hearing difficulty/problems with background noise	0.3	0.4	1.6	-0.4	-0.2	-0.1	-1.0	-0.8	-1.3	-0.1	-0.3	-0.8	-0.4	-0.4
Qualifications: None of the above	0.3	0.5	1.3	0.8	-0.9	-1.2	-0.0	-0.9	-0.7	-0.8	-0.3	-0.7	-0.6	-0.3
Financial difficulties in last 2 years	0.3	0.3	3.1	0.1	1.8	0.2	-0.3	0.0	0.1	0.4	0.3	0.0	0.5	0.3
Neuroticism score	0.3	0.6	2.6	0.9	1.6	0.5	-1.1	-0.2	0.4	0.4	0.4	0.0	0.6	0.4
Alcohol intake versus 10 years previously	0.3	0.5	2.8	-0.4	1.7	-0.2	-0.2	-0.6	-0.4	-0.4	-0.8	-0.5	-0.5	-0.8
Worrier / anxious feelings	0.3	0.6	2.4	-0.6	1.5	0.8	-1.1	-0.8	-0.6	-0.0	-0.6	-0.8	-0.2	-0.5
Mouth/teeth dental problems: Dentures	0.3	0.6	2.0	1.4	0.5	-0.0	-0.5	-1.2	-0.0	-0.6	-0.8	-0.6	-0.5	-0.8
Lung cancer (father)	0.3	0.3	2.2	-0.6	-0.0	-0.5	1.5	-0.1	-0.2	0.2	-0.5	0.0	-0.4	-0.4
Pulse wave Arterial Stiffness index	0.3	0.3	1.6	0.0	-0.7	1.3	0.6	0.4	0.2	0.0	0.2	0.6	-0.2	0.2
Breastfed as a baby	0.3	0.3	2.5	-0.4	-0.4	0.5	1.6	0.6	-0.2	-0.0	0.1	0.2	-0.2	0.2
Medication for cholesterol, blood pressure or diabetes	0.3	0.4	2.6	0.2	-1.3	-1.6	0.6	-0.1	0.0	-0.3	-0.2	0.0	-0.2	-0.1
Forced vital capacity (FVC), Best measure	0.3	0.9	6.7	-1.4	-0.3	-2.6	1.2	0.1	-0.4	-0.2	-0.1	-0.3	-0.1	-0.1
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.4	2.1	0.6	1.5	0.3	-0.2	-0.1	-0.2	0.6	0.6	0.4	0.1	0.6
Pulse wave peak to peak time	0.3	0.3	2.6	-0.3	0.6	-1.6	-0.3	-0.1	-0.1	0.1	-0.1	-0.5	0.4	-0.1
Health satisfaction	0.3	0.4	1.4	-0.5	1.2	-0.7	0.8	-0.1	-0.0	-0.8	-0.1	-0.0	-0.6	-0.1
Mouth/teeth dental problems: Loose teeth	0.3	0.3	1.1	-0.3	1.0	-0.4	1.0	0.3	0.8	0.7	-0.2	0.2	0.4	-0.2
Pulse rate, automated reading	0.3	0.8	1.2	-0.8	0.1	0.3	-0.9	-1.0	-1.1	-1.0	-1.1	-1.0	-1.0	-1.0
Chest pain or discomfort	0.3	0.4	2.3	0.2	-0.4	-1.5	-0.2	-0.8	-0.8	-0.3	-0.3	-0.7	-0.2	-0.2
Age at last live birth	0.3	0.4	3.1	0.4	-0.7	1.8	0.2	0.2	0.3	0.5	-0.1	-0.0	0.4	-0.1
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.4	1.4	-0.5	0.2	-1.0	-1.2	-0.8	-0.1	-0.2	-0.5	-0.8	-0.1	-0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.4	0.7	0.5	0.6	0.5	-0.2	0.4	0.8	0.5	0.7	0.7	0.7	0.7
Illnesses of siblings: Diabetes	0.3	0.3	1.8	-0.1	0.6	1.3	-0.2	-0.2	-0.3	-0.5	-0.5	-0.4	-0.5	-0.5
Mood swings	0.3	0.6	1.7	1.3	1.3	0.6	0.1	0.4	1.1	0.3	0.3	0.6	0.6	0.3
Mouth/teeth dental problems: Mouth ulcers	0.3	0.4	3.2	0.7	-1.8	-0.0	-0.3	0.6	0.1	-0.3	0.3	0.2	0.1	0.4
Number of self-reported non-cancer illnesses	0.3	0.5	3.5	0.1	1.1	1.9	-0.4	-0.1	0.3	0.2	0.1	0.1	0.3	0.1
Ever smoked	0.3	0.6	2.3	-1.4	-0.2	-1.2	1.5	0.6	-0.2	-0.2	0.3	0.2	-0.3	0.3
Fractured/broken bones in last 5 years	0.3	0.4	1.5	1.2	0.6	0.5	0.4	-0.2	0.8	0.6	0.5	0.4	0.7	0.5
Age started oral contraceptive pill	0.3	0.4	1.1	-0.4	0.4	0.4	0.6	0.3	0.8	1.1	0.3	0.6	0.7	0.3
Medication: Omeprazole (e.g. Zanprol)	0.3	0.3	1.1	-1.1	-0.2	-0.4	1.0	0.1	-0.5	-0.5	-0.4	-0.0	-0.7	-0.4
Bipolar Disorder (2018)	0.2	0.2	1.2	-0.5	-0.3	0.7	-1.1	-0.3	-0.4	-0.2	-0.3	-0.2	-0.3	-0.3
Depressed Affect (Nagel 2018)	0.2	0.5	2.9	1.1	1.7	-0.2	0.1	0.1	0.7	0.7	0.2	0.2	0.7	0.2
Neuroticism (Nagel 2018)	0.2	0.5	1.5	0.4	1.2	0.0	-1.2	-0.9	-0.5	-0.2	-0.6	-0.9	-0.2	-0.6
Breast Cancer	0.2	0.4	2.6	0.9	-0.1	-1.6	0.7	-0.6	0.1	-0.6	0.2	-0.0	-0.3	0.2
Prostate Cancer	0.2	0.2	1.1	-0.9	0.2	0.2	1.1	0.4	0.4	-0.0	-0.4	0.2	-0.2	-0.4
Bipolar Disorder (2011)	0.2	0.2	0.7	-0.3	-0.5	-0.8	-0.3	0.1	-0.2	0.5	0.1	-0.1	0.3	0.2
LDL Cholesterol	0.2	0.4	1.7	-0.6	1.3	1.1	0.5	0.5	0.2	0.4	-0.2	0.3	0.2	-0.1
Chronotype (morning person)	0.2	0.4	1.6	1.0	0.3	0.4	-1.2	0.4	0.2	0.5	0.7	0.3	0.5	0.7
Tanning	0.2	1.9	4.1	-0.3	-0.1	0.0	-0.5	1.2	1.7	1.6	2.0	1.6	1.8	2.0
Relative age of first facial hair	0.2	0.5	1.1	0.1	-0.2	-0.3	0.7	0.6	0.8	0.8	1.0	1.0	0.7	1.0
Ever used hormone-replacement therapy (HRT)	0.2	0.2	0.9	-0.2	-1.0	0.1	0.1	0.4	-0.0	0.4	0.6	0.4	0.2	0.6
Vitamin and mineral supplements	0.2	0.2	2.0	-1.4	-0.1	-0.3	-0.0	0.5	-0.5	0.2	0.0	0.0	-0.1	0.1
Body mass index (BMI)	0.2	0.7	5.0	-0.3	0.6	-2.2	1.5	-0.2	0.4	-0.0	0.2	0.1	0.2	0.2
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.4	1.4	1.0	-1.2	-0.2	-0.8	-0.7	-0.5	-0.3	-0.2	-0.5	-0.2	-0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	0.9	1.0	0.1	0.8	-0.7	-0.2	0.6	-0.3	0.4	0.3	0.2	0.4
Loud music exposure frequency	0.2	0.2	0.9	1.0	0.3	-0.4	0.4	0.1	0.7	0.7	0.2	0.2	0.5	0.2
Gout (self-reported)	0.2	0.3	0.6	0.1	0.3	0.8	0.5	0.5	0.6	0.7	0.4	0.3	0.8	0.4
Medication: Ventolin 100micrograms inhaler	0.2	0.3	0.8	0.1	-0.9	-0.3	-0.5	-0.2	-0.5	-0.7	-0.5	-0.6	-0.4	-0.5
Chronic bronchitis/emphysema (mother)	0.2	0.2	0.6	0.5	-0.7	0.1	0.5	0.2	0.2	-0.1	-0.8	-0.0	-0.3	-0.8
Comparative body size at age 10	0.2	0.6	4.3	0.2	0.6	2.1	0.1	-0.4	-0.8	-0.7	0.0	-0.1	-0.9	0.0
Wheeze or whistling in the chest in last year	0.2	0.3	1.4	0.8	0.1	0.4	-1.2	-0.8	-0.7	0.1	-0.1	-0.7	0.1	-0.1
Age at first live birth	0.2	0.4	3.0	0.0	-1.0	1.7	-0.1	0.1	0.3	-0.1	-0.5	-0.2	-0.0	-0.5
Medication: Allopurinol	0.2	0.2	0.7	-0.5	0.8	0.5	-0.0	-0.1	-0.6	0.0	-0.4	-0.6	0.1	-0.4
Medication: Omeprazole	0.2	0.2	0.7	-0.6	-0.3	-0.1	0.8	0.3	-0.2	-0.7	-0.4	-0.0	-0.7	-0.4
Medication: Seretide 50 evohaler	0.2	0.3	0.8	0.2	-0.2	0.9	0.2	0.7	0.9	0.3	0.1	0.4	0.5	0.1
Handedness (chirality/laterality): Left-handed	0.2	0.2	0.8	-0.5	-0.9	0.7	-0.4	-0.0	0.4	0.4	0.0	0.0	0.5	0.0
Loneliness, isolation	0.2	0.2	0.6	-0.8	0.7	-0.3	0.5	0.3	0.2	0.3	0.5	0.4	0.4	0.5
Mineral and other dietary supplements	0.2	0.2	0.7	-0.3	0.7	0.1	-0.5	-0.4	-0.8	0.7	0.1	-0.3	0.2	0.1
Risk taking	0.2	0.3	1.0	0.7	0.1	0.9	-1.0	-0.4	-0.6	0.4	0.1	-0.3	0.3	0.1
Ever had prostate specific antigen (PSA) test	0.2	0.2	0.5	-0.1	0.2	-0.7	0.7	0.3	0.1	0.5	0.7	0.3	0.4	0.7
Basal cell carcinoma (self-reported)	0.2	0.3	1.2	1.1	-0.2	1.1	-0.1	0.4	0.3	-0.3	0.1	0.5	-0.2	0.2
Bipolar Disorder or Schizophrenia	0.1	0.3	0.6	0.1	-0.8	0.3	-0.6	-0.4	-0.2	-0.6	-0.6	-0.5	-0.4	-0.6
Schizophrenia (2018)	0.1	0.2	0.3	0.5	0.1	-0.3	0.1	-0.3	-0.0	-0.6	-0.6	-0.4	-0.3	-0.6
Blood Eosinophil Count	0.1	0.7	3.1	-1.8	-0.9	-0.3	1.5	1.0	0.4	-0.1	0.3	0.7	-0.1	0.3
Neuroticism	0.1	0.4	1.7	-0.1	1.3	0.0	-0.9	-0.6	-0.5	0.1	-0.4	-0.7	-0.0	-0.4
Hearing difficulty/problems: Yes	0.1	0.2	1.1	0.5	-0.1	-0.1	-1.1	-0.2	-0.5	-0.1	-0.3	-0.5	-0.2	-0.3
Fed-up feelings	0.1	0.2	0.4	0.6	0.1	-0.0	-0.5	-0.0	0.1	0.6	0.6	0.5	0.4	0.6
Stomach or abdominal pain in last month	0.1	0.1	1.5	-0.2	-1.2	-0.0	-0.1	-0.2	-0.0	-0.2	0.1	-0.0	-0.1	0.1
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.2	0.7	0.7	0.8	0.2	-0.8	-0.2	0.0	0.1	0.2	-0.3	0.3	0.2
Fluid intelligence score	0.1	0.2	0.8	-0.4	0.2	0.9	0.1	0.5	0.5	0.7	0.2	0.5	0.5	0.2
Qualifications: A levels/AS levels or equivalent	0.1	0.2	0.5	0.4	0.2	0.7	0.7	0.4	0.2	0.7	0.3	0.5	0.4	0.3
Qualifications: College or University degree	0.1	0.2	0.7	-0.4	-0.8	0.0	0.8	-0.1	0.1	0.0	-0.3	0.2	-0.3	-0.3
Had major operations	0.1	0.1	0.5	-0.3	0.7	-0.5	0.1	0.1	-0.0	0.2	-0.4	-0.3	0.2	-0.4
Commuting to job workplace: Car/motor vehicle	0.1	0.1	0.3	-0.3	-0.6	-0.2	0.5	-0.2	-0.3	-0.4	-0.4	-0.1	-0.5	-0.4
Schizophrenia (2014)	0.0	0.1	0.5	0.0	0.1	-0.7	0.3	0.0	0.6	-0.2	-0.1	0.1	0.1	-0.1
Hair Pigment	0.0	0.4	1.0	-0.4	0.3	0.2	1.0	0.3	-0.6	-0.6	-1.0	-0.3	-0.9	-1.0

Hub : Genes

LYPLAL1

Models

Trait associations