[Hub]/) : Traits : Body fat percentage :

chr4:69,713-1,610,872

Best TWAS P=1.32e-12 · Best GWAS P=2.65e-09 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex SLC26A1 0.12 0.06 bslmm 400 0.08 8.0e-10 5.2 6.2 4.6e-10 0.51 0.08 0.92 TRUE
2 GTEx Adipose Subcutaneous SLC26A1 0.37 0.32 lasso 4 0.32 5.7e-27 5.3 5.4 6.9e-08 0.55 0.06 0.94 FALSE
3 GTEx Adipose Subcutaneous CPLX1 0.20 0.11 lasso 6 0.11 2.5e-09 -5.2 5.2 2.1e-07 0.08 0.08 0.92 FALSE
4 GTEx Adipose Subcutaneous RP11-440L14.1 0.58 0.38 enet 36 0.48 1.9e-43 -2.8 5.2 1.9e-07 0.16 0.99 0.00 FALSE
5 GTEx Adipose Visceral Omentum SLC26A1 0.47 0.36 lasso 7 0.36 1.8e-19 5.3 5.4 6.8e-08 0.59 0.06 0.94 FALSE
6 GTEx Artery Aorta SLC26A1 0.42 0.37 lasso 6 0.38 6.4e-22 5.2 5.4 5.4e-08 0.54 0.06 0.94 FALSE
7 GTEx Artery Tibial SLC26A1 0.33 0.35 lasso 3 0.36 3.2e-29 5.3 5.2 1.8e-07 0.56 0.06 0.94 FALSE
8 GTEx Artery Tibial GAK 0.19 0.03 enet 29 0.10 2.4e-08 -3.0 6.0 2.1e-09 0.59 0.01 0.99 FALSE
9 GTEx Brain Caudate basal ganglia SLC26A1 0.27 0.13 lasso 2 0.18 6.8e-06 5.3 5.1 2.8e-07 0.50 0.06 0.85 FALSE
10 GTEx Brain Cerebellar Hemisphere SLC26A1 0.33 0.14 lasso 8 0.15 1.0e-04 5.3 5.5 3.1e-08 0.55 0.09 0.67 FALSE
11 GTEx Brain Cerebellum SLC26A1 0.61 0.41 enet 22 0.46 2.1e-15 5.2 6.2 5.2e-10 0.57 0.07 0.93 FALSE
12 GTEx Brain Cortex SLC26A1 0.45 0.35 lasso 3 0.33 6.9e-10 5.2 5.5 3.6e-08 0.54 0.06 0.93 FALSE
13 GTEx Brain Frontal Cortex BA9 SLC26A1 0.30 0.24 lasso 3 0.15 8.0e-05 5.3 5.3 1.4e-07 0.56 0.06 0.82 FALSE
14 GTEx Breast Mammary Tissue SLC26A1 0.34 0.31 lasso 4 0.29 2.7e-15 5.3 5.3 8.9e-08 0.62 0.06 0.94 FALSE
15 GTEx Breast Mammary Tissue (Male) SLC26A1 0.17 0.24 lasso 1 0.19 4.4e-05 5.3 5.3 1.4e-07 0.56 0.05 0.54 FALSE
16 GTEx Cells Transformed fibroblasts SLC26A1 0.36 0.22 enet 24 0.26 1.4e-19 5.3 5.3 8.7e-08 0.62 0.09 0.91 FALSE
17 GTEx Colon Sigmoid SLC26A1 0.45 0.48 lasso 3 0.48 6.7e-19 5.3 5.4 8.4e-08 0.56 0.06 0.94 FALSE
18 GTEx Colon Transverse SLC26A1 0.26 0.23 lasso 4 0.22 9.7e-11 5.2 5.2 1.9e-07 0.58 0.08 0.92 FALSE
19 GTEx Esophagus Gastroesophageal Junction SLC26A1 0.44 0.33 lasso 6 0.35 1.8e-13 5.3 5.2 2.5e-07 0.44 0.07 0.93 FALSE
20 GTEx Esophagus Mucosa SLC26A1 0.45 0.39 enet 15 0.40 2.5e-28 5.2 5.2 2.2e-07 0.52 0.07 0.93 FALSE
21 GTEx Esophagus Muscularis SLC26A1 0.38 0.37 lasso 4 0.36 4.3e-23 5.3 5.5 4.9e-08 0.57 0.06 0.94 FALSE
22 GTEx Heart Atrial Appendage SLC26A1 0.44 0.39 lasso 6 0.37 8.0e-18 4.9 5.3 8.8e-08 0.60 0.14 0.86 FALSE
23 GTEx Heart Left Ventricle SLC26A1 0.22 0.13 enet 10 0.17 1.4e-09 5.2 5.3 1.2e-07 0.49 0.07 0.93 FALSE
24 GTEx Lung SLC26A1 0.51 0.41 lasso 9 0.42 1.2e-34 5.3 5.4 5.9e-08 0.56 0.06 0.94 FALSE
25 GTEx Muscle Skeletal DGKQ 0.15 0.07 enet 15 0.09 6.6e-09 5.3 5.4 6.7e-08 0.57 0.06 0.94 TRUE
26 GTEx Muscle Skeletal SLC26A1 0.16 0.12 lasso 6 0.12 1.7e-11 5.3 5.3 1.1e-07 0.63 0.07 0.93 FALSE
27 GTEx Nerve Tibial SLC26A1 0.55 0.49 lasso 4 0.50 1.0e-40 5.2 5.3 9.7e-08 0.56 0.07 0.93 FALSE
28 GTEx Nerve Tibial CPLX1 0.26 0.05 lasso 5 0.09 1.1e-06 -5.3 5.4 5.6e-08 0.16 0.09 0.91 FALSE
29 GTEx Pituitary SLC26A1 0.37 0.38 enet 14 0.33 3.9e-09 5.3 5.8 8.2e-09 0.65 0.06 0.93 TRUE
30 GTEx Skin Not Sun Exposed Suprapubic SLC26A1 0.55 0.38 lasso 8 0.40 2.7e-23 5.2 5.2 1.5e-07 0.52 0.06 0.93 FALSE
31 GTEx Skin Sun Exposed Lower leg SLC26A1 0.48 0.38 lasso 5 0.41 6.2e-36 5.2 5.2 2.3e-07 0.57 0.08 0.92 FALSE
32 GTEx Spleen SLC26A1 0.35 0.19 lasso 4 0.25 4.7e-07 5.3 5.5 2.8e-08 0.56 0.08 0.86 FALSE
33 GTEx Stomach SLC26A1 0.26 0.17 enet 14 0.16 4.0e-08 5.2 6.5 7.8e-11 0.63 0.06 0.94 TRUE
34 GTEx Thyroid SLC26A1 0.53 0.46 lasso 8 0.46 1.3e-38 5.2 5.3 1.4e-07 0.58 0.06 0.93 FALSE
35 GTEx Vagina SLC26A1 0.26 0.41 lasso 1 0.37 2.4e-09 5.3 5.3 1.4e-07 0.56 0.07 0.91 FALSE
36 GTEx Whole Blood SLC26A1 0.07 0.05 enet 13 0.07 3.0e-07 -4.4 5.3 9.3e-08 0.53 0.23 0.76 TRUE
37 METSIM Adipose SLC26A1 0.16 0.13 enet 10 0.13 2.1e-18 5.2 5.5 4.4e-08 0.48 0.06 0.94 FALSE
38 NTR Blood PCGF3 0.07 0.00 enet 33 0.02 7.7e-08 4.2 5.5 3.4e-08 0.27 0.36 0.58 TRUE
39 ROSMAP Brain Pre-frontal Cortex DGKQ 0.37 0.36 lasso 6 0.38 1.9e-51 5.2 5.3 9.1e-08 0.57 0.07 0.93 FALSE
40 The Cancer Genome Atlas Bladder Urothelial Carcinoma SLC26A1 0.05 0.01 blup 53 0.02 1.2e-02 4.1 5.5 5.1e-08 0.58 0.06 0.47 FALSE
41 The Cancer Genome Atlas Breast Invasive Carcinoma PCGF3 0.03 0.00 blup 69 0.01 3.7e-03 4.2 7.1 1.3e-12 0.34 0.02 0.40 TRUE
42 The Cancer Genome Atlas Brain Lower Grade Glioma PCGF3 0.08 0.02 lasso 4 0.07 1.9e-08 -4.1 5.2 2.3e-07 0.14 0.03 0.86 FALSE
43 The Cancer Genome Atlas Testicular Germ Cell Tumors PCGF3 0.13 0.00 blup 69 0.04 1.4e-02 -5.3 5.6 1.8e-08 0.10 0.01 0.76 FALSE