TWAS hub - CPLX1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.2020	0.0520	2.8e-06	0.113	NA	0.094	NA	0.111	1.8e-09	NA	4.3e-08	NA	2.5e-09
2	GTEx	Artery Tibial	0.1222	0.0420	8.5e-04	0.044	NA	0.003	NA	0.020	2.3e-04	NA	1.8e-01	NA	9.6e-03
3	GTEx	Brain Cerebellum	0.2500	0.0920	3.5e-03	0.090	NA	0.145	NA	0.162	1.3e-03	NA	4.7e-05	NA	1.6e-05
4	GTEx	Breast Mammary Tissue	0.1250	0.0520	9.4e-03	0.107	NA	0.091	NA	0.095	3.9e-06	NA	2.2e-05	NA	1.3e-05
5	GTEx	Breast Mammary Tissue (Male)	0.2354	0.1203	4.4e-02	0.015	NA	-0.013	NA	0.060	1.5e-01	NA	8.7e-01	NA	1.7e-02
6	GTEx	Breast Mammary Tissue (Female)	0.1144	0.0779	8.4e-02	0.078	NA	0.032	NA	0.089	2.5e-03	NA	3.8e-02	NA	1.3e-03
7	GTEx	Esophagus Mucosa	0.1070	0.0440	5.1e-03	-0.001	NA	0.031	NA	0.005	4.0e-01	NA	3.5e-03	NA	1.3e-01
8	GTEx	Heart Left Ventricle	0.1828	0.0551	1.2e-04	0.051	NA	0.044	NA	0.057	1.0e-03	NA	2.1e-03	NA	5.7e-04
9	GTEx	Lung	0.1451	0.0499	7.2e-04	0.077	NA	0.056	NA	0.070	1.7e-06	NA	4.2e-05	NA	5.1e-06
10	GTEx	Nerve Tibial	0.2612	0.0752	2.4e-05	0.054	NA	0.078	NA	0.086	1.0e-04	NA	3.6e-06	NA	1.1e-06
11	GTEx	Ovary	0.4350	0.1460	3.4e-03	0.074	NA	0.132	NA	0.124	7.1e-03	NA	3.9e-04	NA	5.9e-04
12	GTEx	Thyroid	0.1740	0.0460	2.1e-06	0.066	NA	0.126	NA	0.083	8.6e-06	NA	7.2e-10	NA	6.7e-07
13	TCGA	Kidney Renal Clear Cell Carcinoma	0.0993	0.0397	2.0e-04	0.038	0.029	0.025	NA	0.043	3.7e-05	0.00028	7.6e-04	NA	1.1e-05
14	TCGA	Pancreatic Adenocarcinoma	0.1780	0.0720	1.3e-03	0.057	0.068	0.061	NA	0.046	2.0e-03	0.00084	1.5e-03	NA	5.4e-03
15	TCGA	Thyroid Carcinoma	0.0810	0.0350	3.9e-04	0.017	0.034	0.067	NA	0.044	7.1e-03	0.00028	4.4e-07	NA	3.9e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15
Headache pain in last month	5.1	8.8	14.9	-3.6	-2.6	-0.5	-3.3	-3.3	-2.7	-2.1	-3.6	-3.2	-3.5	-3.8	-3.9	-0.7	-2.4	-2.7
Commuting to job workplace: Walk	5.0	5.4	11.2	2.8	1.8	0.3	2.7	2.6	3.4	1.6	2.6	3.1	2.7	2.0	1.5	1.4	2.5	2.3
Eye problems/disorders: Glaucoma	4.9	5.9	12.5	-3.2	-2.4	-0.4	-2.8	-1.9	-1.7	-3.5	-2.4	-2.5	-3.2	-3.3	-2.4	-0.8	-1.7	-1.4
Nervous feelings	4.8	9.0	17.4	-3.1	-4.2	1.8	-3.4	-1.7	-2.4	-3.8	-2.7	-3.1	-3.5	-3.1	-2.8	-1.8	-3.9	-2.0
Worry (Nagel 2018)	4.5	9.4	16.3	-3.5	-4.0	1.5	-3.5	-2.7	-2.5	-3.1	-3.2	-3.2	-3.5	-3.5	-3.6	-1.6	-3.3	-1.7
Breast Cancer	4.3	10.4	18.3	3.9	3.2	-2.2	4.0	1.4	3.4	3.9	3.7	4.0	3.9	2.8	2.6	1.1	4.3	1.3
Body fat percentage	4.3	17.0	29.5	5.2	5.0	1.8	5.1	3.2	4.1	3.9	4.8	5.0	5.4	4.0	5.0	1.4	2.5	2.3
Heel T-Score	4.1	32.2	148.8	-5.2	-5.3	2.6	-4.7	12.2	-2.9	-4.8	-5.9	-4.4	-5.7	-4.5	-7.1	-2.5	-6.3	-3.8
Leg fat percentage (right)	4.0	14.5	26.2	4.7	4.8	1.9	4.5	2.8	3.3	4.0	4.4	4.2	5.1	4.0	5.0	1.4	2.0	2.1
Medication: Lansoprazole	3.8	4.4	8.6	-2.3	-1.1	1.0	-2.5	-2.4	-2.3	-1.2	-2.8	-2.9	-2.2	-1.6	-1.2	0.3	-2.9	-2.3
Chronic bronchitis/emphysema (mother)	3.8	4.5	7.3	-2.7	-2.7	-0.4	-2.4	-1.7	-2.1	-1.5	-2.3	-2.2	-2.6	-2.2	-2.4	-1.5	-1.9	-1.9
Commuting to job workplace: Car/motor vehicle	3.8	4.4	20.0	-2.1	-1.0	-0.9	-2.3	-2.3	-4.5	0.2	-2.4	-2.6	-1.7	-0.1	-1.4	-2.0	-1.7	-2.0
Illness, injury, bereavement, stress in last 2 years	3.8	4.7	8.4	2.3	1.6	-1.0	2.8	1.9	2.3	1.5	2.3	2.9	2.3	2.5	2.3	1.7	2.6	1.8
Commuting to job workplace: Public transport	3.8	4.6	14.1	2.4	1.6	-0.0	2.6	1.8	3.8	0.8	2.0	2.5	2.1	1.1	2.3	2.4	2.4	1.7
Leg fat percentage (left)	3.8	13.7	24.1	4.6	4.5	1.8	4.4	2.8	3.6	3.8	4.2	4.2	4.9	3.9	4.7	1.5	2.0	1.7
Trunk fat percentage	3.7	14.7	25.8	4.8	4.7	1.7	4.7	3.1	3.9	3.5	4.5	4.7	5.1	3.4	4.5	1.3	2.4	2.1
Relative age of first facial hair	3.5	7.1	13.3	-3.3	-3.5	0.5	-3.6	-2.7	-2.8	-1.2	-2.7	-3.2	-3.2	-2.2	-3.3	-1.0	-2.7	-1.1
Crohns Disease (2012)	3.2	5.2	10.2	-2.7	-1.9	-0.9	-2.8	-2.2	-2.5	-1.1	-2.5	-3.0	-2.5	-2.5	-3.2	-0.1	-2.0	-1.9
Neuroticism	3.2	7.8	14.2	-3.0	-3.8	1.9	-3.3	-2.9	-3.0	-2.5	-3.1	-3.3	-2.6	-2.9	-2.6	-1.1	-3.4	-1.2
Severe depression (siblings)	3.2	3.5	6.4	-2.2	-1.7	0.5	-2.4	-0.8	-2.5	-1.5	-1.6	-2.3	-2.3	-1.6	-1.3	-1.3	-2.5	-2.3
Number of incorrect matches in round	3.1	5.1	9.8	-2.5	-2.2	3.0	-2.6	-1.5	-2.3	-1.8	-2.7	-2.6	-1.7	-3.1	-1.9	1.2	-2.7	0.5
Alzheimer’s Disease (in mother)	3.0	3.5	14.4	-1.9	-1.4	-1.2	-1.7	-0.6	-1.5	-2.1	-1.8	-1.7	-2.4	-0.9	-1.7	-2.2	-1.0	-3.8
Alzheimer’s Disease (including proxy)	3.0	4.3	11.6	-2.2	-2.2	-0.1	-2.1	-1.6	-1.6	-2.7	-2.5	-2.1	-2.6	-1.8	-1.8	-0.5	-1.4	-3.4
Tense / ‘highly strung’	3.0	5.0	11.8	-2.7	-3.4	0.1	-2.6	-1.8	-1.2	-1.8	-1.7	-2.3	-2.8	-2.8	-3.0	-0.8	-2.7	-0.7
Eye problems/disorders: None of the above	3.0	3.5	6.3	2.2	1.1	-0.6	2.3	0.5	2.1	1.6	1.8	2.4	2.3	2.5	2.0	1.4	2.2	1.1
Medication: Seretide 50 evohaler	3.0	3.4	7.5	-2.2	-2.1	-0.7	-2.3	-0.4	-1.8	-1.8	-1.0	-2.3	-2.7	-2.0	-1.0	-2.3	-2.2	-1.2
Family relationship satisfaction	3.0	3.6	7.0	-2.2	-2.6	0.3	-2.4	-0.2	-1.4	-1.6	-1.4	-2.1	-2.4	-2.3	-1.8	-1.9	-2.5	-1.1
Chronic bronchitis/emphysema (father)	2.9	3.4	7.2	-2.1	-1.9	-0.0	-2.3	-0.8	-2.0	-0.6	-1.8	-2.2	-2.0	-2.0	-2.7	-1.2	-1.9	-2.1
Medication: Ibuprofen	2.9	3.5	6.6	-2.6	-1.9	0.5	-2.2	-1.6	-1.9	-1.6	-2.3	-2.1	-2.1	-2.5	-2.3	0.7	-1.5	-0.7
Age when periods started (menarche)	2.8	6.8	13.0	-3.2	-2.9	1.1	-3.3	-2.0	-3.0	-1.7	-3.0	-3.1	-2.7	-3.0	-3.6	-0.6	-2.4	-1.0
Waist circumference	2.8	10.3	20.9	4.0	3.9	1.2	3.7	1.9	3.1	3.7	3.7	3.3	4.1	3.5	4.6	1.8	1.7	0.9
Whole body fat mass	2.8	11.6	18.5	4.3	4.3	1.5	4.2	3.4	3.2	3.2	4.0	4.0	4.3	3.6	4.1	0.9	1.8	1.1
Trunk fat mass	2.7	11.5	18.8	4.2	4.3	1.6	4.1	3.4	3.3	3.0	4.0	4.1	4.3	3.3	4.0	1.2	1.9	1.2
Father’s age at death	2.7	3.7	7.6	2.4	2.0	-0.0	2.3	1.4	1.4	1.6	2.1	2.5	2.7	2.5	1.8	0.0	2.2	1.0
Glaucoma (self-reported)	2.7	3.2	8.8	-2.2	-1.4	-0.0	-2.0	-1.6	-1.2	-3.0	-1.7	-1.9	-2.6	-1.9	-1.4	-0.9	-1.5	-1.4
Leg fat mass (right)	2.7	10.5	18.2	4.0	4.3	1.6	3.8	3.2	2.6	3.5	3.7	3.5	4.1	3.8	4.1	0.8	1.5	0.7
Osteoporosis (self-reported)	2.7	3.4	10.4	-1.8	-1.3	1.7	-1.8	-3.2	-1.0	-2.4	-2.3	-1.8	-1.7	-1.2	-1.4	1.9	-1.4	-1.4
Arm fat percentage (right)	2.6	10.4	18.0	4.1	3.8	2.2	4.0	2.0	3.3	2.9	3.8	3.9	4.2	3.4	4.2	0.9	1.3	1.1
Arm fat percentage (left)	2.6	10.5	18.8	4.2	3.8	2.1	4.0	2.4	3.1	3.1	3.8	3.9	4.3	3.4	4.1	0.9	1.4	1.3
Leg fat mass (left)	2.6	10.1	17.2	3.9	4.2	1.5	3.8	3.3	2.8	3.4	3.6	3.5	3.9	3.7	4.0	0.8	1.5	0.4
Medication for hormone replacement therapy	2.4	2.7	10.4	-1.8	-1.1	0.3	-2.0	-3.2	-1.0	-1.0	-1.7	-2.1	-1.6	-2.0	-1.5	1.3	-1.3	-0.6
Heel bone mineral density (BMD) T-score, automated (left)	2.4	5.3	38.2	-1.4	-2.6	1.9	-1.5	6.2	-0.1	-2.2	-1.7	-1.1	-1.6	-1.4	-2.4	-1.4	-2.4	-0.6
Chest pain or discomfort	2.4	3.5	6.4	-2.2	-1.6	-0.6	-2.2	-1.2	-2.5	-1.2	-1.9	-2.2	-2.2	-1.7	-1.0	-2.4	-1.9	-1.8
Neuroticism (Nagel 2018)	2.3	5.3	11.1	-2.5	-3.3	2.1	-2.7	-1.9	-2.0	-2.7	-2.2	-2.5	-2.0	-2.9	-2.2	-0.8	-2.6	0.6
Neuroticism score	2.3	4.8	11.4	-2.5	-3.4	1.0	-2.8	-1.1	-2.2	-1.1	-2.6	-2.7	-2.2	-2.3	-2.4	-0.1	-2.7	-0.5
Age started oral contraceptive pill	2.3	2.8	6.4	1.8	1.0	-0.7	1.9	2.1	2.3	2.5	2.2	2.2	1.5	1.8	1.3	0.2	1.1	0.4
Crohns Disease (2017)	2.2	4.9	10.9	-2.9	-2.3	0.1	-2.8	-1.8	-2.4	-1.3	-2.5	-2.7	-2.4	-2.2	-3.3	0.4	-1.9	-1.5
Fractured/broken bones in last 5 years	2.2	2.8	7.5	1.4	-0.1	-1.8	1.7	-0.9	2.7	1.3	2.5	2.3	1.0	0.8	2.1	0.3	1.9	1.7
Fasting Glucose	2.1	2.5	7.2	-2.1	-1.2	-0.7	-1.8	-0.8	-1.4	-1.9	-1.4	-1.8	-2.7	-0.9	-1.6	-1.8	-1.6	-0.7
Fluid intelligence score	2.1	4.3	15.2	2.4	1.2	-1.8	2.6	1.9	2.2	0.8	1.3	2.8	2.3	2.0	1.1	1.1	3.9	1.3
Health satisfaction	2.1	2.7	7.5	2.0	2.7	-1.8	1.5	1.2	0.1	2.5	0.7	0.9	1.4	2.1	1.9	-0.2	1.8	-1.3
Qualifications: NVQ or HND or HNC or equivalent	2.1	2.6	5.4	-1.7	-1.4	-0.6	-2.1	-1.8	-1.6	-0.9	-1.8	-2.0	-2.3	-0.6	-0.5	-0.9	-1.6	-2.3
Number of operations (self-reported)	2.1	3.1	6.4	-2.1	-0.8	0.3	-2.0	-0.0	-2.5	-0.8	-1.5	-2.1	-2.5	-1.2	-0.8	-2.0	-2.2	-2.5
Ovarian Cancer	2.0	2.6	5.5	2.1	1.6	-0.3	1.9	1.5	1.3	2.3	2.2	1.9	2.2	0.9	1.3	0.8	1.4	1.0
Medication: Atorvastatin	2.0	2.5	5.2	1.7	1.5	1.9	1.9	0.4	1.1	2.1	1.4	1.9	2.3	1.1	0.6	2.1	0.7	1.6
Waist Hip Ratio (WHR)	1.9	8.6	33.6	3.1	3.4	0.5	2.3	-2.2	2.7	3.2	1.4	1.5	3.6	1.8	3.4	5.8	3.0	2.1
Allergy or Eczema	1.9	5.1	16.4	2.1	1.9	-2.4	2.1	1.9	1.2	1.1	2.6	2.3	1.4	2.5	2.4	-4.0	3.0	-0.8
High blood pressure (siblings)	1.9	2.7	5.7	-1.8	-0.9	1.0	-1.9	-1.3	-2.4	-1.1	-2.0	-2.2	-1.8	-1.0	-1.7	-0.4	-2.3	-1.7
Average weekly beer plus cider intake	1.9	2.7	8.3	2.0	1.8	-0.3	1.5	2.2	0.5	1.8	1.4	1.1	1.6	2.2	2.9	0.4	0.9	1.5
Cholesterol lowering medication	1.9	2.8	10.8	1.4	0.9	2.8	1.0	-0.7	1.5	0.0	1.1	0.7	1.9	-0.1	1.8	2.8	-0.2	3.3
Arm fat mass (right)	1.8	7.6	12.5	3.4	3.5	1.9	3.3	2.6	2.6	2.5	3.2	3.2	3.4	3.2	3.5	0.6	0.9	0.1
Arm fat mass (left)	1.8	7.3	11.6	3.3	3.4	1.8	3.3	2.8	2.5	2.5	3.1	3.2	3.3	3.2	3.3	0.5	0.9	-0.0
Ever smoked	1.8	3.2	12.4	-2.0	-1.6	-0.8	-1.9	-1.2	-1.9	0.3	-1.7	-1.7	-2.6	0.2	-1.8	-1.2	-1.2	-3.5
Pain experienced in last month	1.8	3.1	7.7	1.9	0.1	0.6	1.9	0.3	2.4	0.0	2.3	2.5	2.1	1.2	1.4	0.1	2.3	2.8
Blood Red Count	1.7	16.4	27.8	5.1	4.6	1.4	5.0	3.3	3.1	3.0	4.8	4.7	5.3	5.1	5.2	-0.6	2.9	2.6
Heel bone mineral density (BMD) T-score, automated (right)	1.7	3.8	36.1	-1.0	-1.6	1.4	-1.2	6.0	-0.8	-1.4	-1.5	-1.1	-0.9	-0.9	-1.6	-0.7	-2.0	-0.0
Qualifications: College or University degree	1.7	5.3	16.4	1.8	0.3	-4.1	2.2	2.0	2.5	2.7	2.2	3.0	1.6	1.4	0.9	-0.5	3.7	1.9
BMI	1.6	9.4	20.5	3.9	3.1	0.2	3.4	2.3	2.8	3.0	3.9	3.4	3.6	4.3	4.5	-1.0	1.4	-0.2
Medication: Simvastatin	1.6	2.3	8.3	1.7	1.1	0.1	1.3	0.7	1.0	1.3	1.4	0.9	1.9	1.0	2.5	0.9	1.5	2.9
Medication: Ibuprofen (e.g. Nurofen)	1.6	2.1	4.2	-2.0	-1.8	-0.3	-1.8	-1.2	-1.9	-0.4	-1.6	-1.5	-1.5	-2.0	-1.8	0.3	-1.1	-0.4
Guilty feelings	1.6	2.4	5.6	-1.5	-2.1	0.4	-2.1	-1.8	-2.4	0.2	-1.4	-2.3	-1.0	-1.3	-1.4	-0.3	-1.8	0.7
Intelligence (Savage-Jansen 2018)	1.5	4.5	15.3	2.0	1.0	-2.9	2.4	1.8	2.0	1.3	1.7	2.8	1.9	1.8	1.4	0.9	3.9	1.7
Serious illness, injury or assault of a close relative in last 2 years	1.5	1.7	4.9	-1.6	-1.2	1.0	-1.4	-1.4	-2.2	-1.2	-1.5	-1.2	-1.0	-1.3	-1.1	-1.1	-1.4	-0.7
Loud music exposure frequency	1.5	1.7	5.2	1.1	0.4	-0.8	1.3	0.7	2.0	1.9	2.3	1.5	0.4	0.7	1.0	-2.1	0.5	0.2
Alcohol intake frequency.	1.5	3.4	6.3	2.3	0.6	1.8	1.8	2.0	2.5	1.2	2.4	1.9	2.5	1.2	1.9	1.0	0.6	2.3
Number of full sisters	1.5	1.9	5.3	-0.7	-1.0	1.6	-1.4	-2.3	-1.2	-1.6	-1.3	-1.6	-0.9	-0.8	-0.6	-0.6	-1.9	-1.7
Leg pain on walking	1.5	1.9	7.0	-1.0	-1.2	-2.6	-1.5	1.1	-1.9	1.1	-0.8	-1.4	-1.2	-0.2	-0.9	-2.2	-0.3	-0.7
Medication for cholesterol	1.5	2.2	8.6	0.7	0.5	-2.9	1.0	2.9	0.1	1.3	0.8	1.3	0.2	1.1	0.2	-2.4	1.5	-1.0
Financial situation satisfaction	1.5	1.9	6.0	1.1	1.7	-1.1	1.4	2.2	0.4	1.0	1.5	1.1	0.3	1.5	1.6	-2.4	0.5	-0.7
Rheumatoid Arthritis	1.4	2.0	5.1	-2.0	-1.6	-1.2	-1.5	-0.7	-1.5	-1.0	-1.2	-1.4	-2.3	-1.2	-1.2	-0.8	-0.9	-1.6
Blood White Count	1.4	10.0	63.4	2.0	-0.6	-3.0	2.1	4.7	2.7	0.4	3.8	2.9	0.4	1.4	2.2	-8.0	2.8	1.4
Frequency of depressed mood in last 2 weeks	1.4	2.0	4.9	-1.6	-1.8	-0.7	-1.7	0.5	-2.2	-1.2	-1.7	-1.6	-1.3	-1.9	-1.5	-0.9	-0.7	0.1
Hayfever/allergic rhinitis (self-reported)	1.4	1.8	4.7	1.1	1.5	-1.0	1.1	2.1	-0.3	1.5	1.1	0.9	0.8	1.7	1.4	-2.2	1.6	-0.3
Illnesses of siblings	1.4	2.0	4.5	1.1	0.5	-1.8	1.4	2.1	1.5	1.8	1.6	1.7	0.8	0.8	0.6	-1.4	2.0	0.3
Worrier / anxious feelings	1.4	2.7	8.3	-1.9	-2.9	-1.0	-1.9	-0.9	-0.9	-0.9	-2.1	-1.9	-2.2	-1.8	-1.9	-0.5	-1.1	-1.0
Pulse wave reflection index	1.4	1.7	3.6	1.4	1.3	0.5	1.3	-1.9	0.9	-0.9	1.0	1.2	1.7	1.6	1.6	1.0	1.5	0.9
Basal cell carcinoma (self-reported)	1.4	1.7	6.1	1.3	0.5	0.5	1.4	1.9	1.9	2.5	2.0	1.6	0.9	0.5	0.3	-0.8	0.3	0.3
Alzheimer’s Disease (in father)	1.3	1.4	3.4	-1.1	-1.8	0.9	-1.4	-1.5	-0.8	-0.7	-1.5	-1.3	-1.1	-1.3	-0.7	1.5	-1.2	-0.4
Lung FEV1/FVC ratio	1.3	6.5	16.4	3.4	2.7	1.5	2.9	1.3	1.2	2.3	1.8	2.5	4.0	3.5	1.9	3.1	2.4	1.5
Body mass index (BMI)	1.3	5.7	11.0	2.9	2.9	1.4	2.8	2.0	1.8	2.7	2.7	2.6	2.9	3.3	3.2	-0.2	0.7	-0.6
Had other major operations	1.3	1.6	3.3	-1.8	-0.4	0.9	-1.5	-0.7	-1.8	-0.7	-1.4	-1.6	-1.4	-1.8	-1.4	-0.4	-1.2	-0.6
Hair/balding pattern: Pattern 4	1.3	3.2	15.8	-1.2	-0.7	1.7	-1.0	-1.6	0.5	-2.6	-2.5	-1.5	-0.7	-2.1	-1.6	4.0	-0.9	0.2
Blood clot in the leg (DVT)	1.3	1.6	3.0	-1.6	-0.4	0.3	-1.5	0.6	-1.4	-1.6	-1.0	-1.6	-1.7	-1.7	-1.4	-0.5	-1.5	-0.6
Emphysema/chronic bronchitis	1.3	1.5	4.3	-1.3	-1.1	1.2	-0.9	-1.2	-0.7	-1.8	-0.8	-0.9	-1.4	-1.6	-0.6	-2.1	-0.8	-0.8
Migraine (self-reported)	1.3	1.6	3.1	1.8	1.3	0.6	1.6	0.1	0.4	0.6	1.7	1.4	1.8	1.2	1.4	-0.1	1.3	1.5
Medication: Omeprazole	1.3	1.5	3.0	1.6	1.0	0.6	1.4	1.7	1.2	1.4	1.4	1.1	1.2	0.5	1.7	-1.1	1.1	0.6
Suffer from ‘nerves’	1.3	2.1	5.4	-1.3	-1.6	1.9	-1.7	-1.0	-1.6	-1.0	-1.5	-1.9	-1.2	-1.3	-1.2	-0.3	-2.3	-0.4
Had major operations	1.3	1.5	6.7	-0.6	-1.0	-1.4	-1.1	0.9	-1.4	0.1	-0.6	-1.0	-1.3	-0.1	0.4	-2.6	-1.0	-2.2
Back pain experienced in last month	1.3	1.8	6.6	-1.4	-1.0	-0.2	-1.4	-0.1	-1.7	-0.6	-1.7	-1.8	-1.4	-0.7	-1.1	-0.7	-1.5	-2.6
Ever had prostate specific antigen (PSA) test	1.3	1.6	5.5	-1.1	-1.6	-1.1	-1.2	-0.6	-1.3	-1.3	-1.0	-1.0	-1.5	-1.3	-1.4	-2.3	-0.3	-0.1
Verbal and Numeric Reasoning (VNR)	1.2	2.8	6.9	2.0	0.8	-0.3	1.8	1.7	1.9	0.4	0.7	1.9	2.0	1.2	1.1	2.2	2.6	2.1
Qualifications: CSEs or equivalent	1.2	1.6	10.6	-0.4	0.2	2.4	-0.7	-0.6	-0.3	-1.2	-0.8	-0.9	-0.6	0.4	0.4	-0.9	-1.6	-3.2
Mouth/teeth dental problems: Bleeding gums	1.2	1.5	8.1	0.3	-0.5	-2.3	0.7	2.8	1.3	0.8	1.1	1.1	-0.1	0.3	0.4	-1.6	1.1	0.1
Worry too long after embarrassment	1.2	1.9	4.2	-1.4	-1.7	1.0	-1.6	-1.8	-1.1	-0.7	-2.1	-1.9	-1.0	-1.3	-1.4	1.3	-1.0	0.8
Reason for reducing amount of alcohol drunk: Health precaution	1.2	1.4	2.6	1.1	1.5	-1.5	1.2	0.9	-0.5	0.3	1.1	1.2	0.8	1.6	0.9	-1.6	1.5	1.0
Overall health rating	1.2	2.7	5.8	-1.3	-1.4	-0.6	-2.0	0.8	-1.4	-0.9	-1.8	-2.2	-2.1	-1.6	-1.1	-2.1	-1.5	-2.4
Supplements: Vitamin C	1.2	1.4	5.8	0.6	0.4	-2.4	0.4	0.6	0.4	1.8	0.2	0.4	1.3	0.3	-0.4	1.4	2.2	1.5
Medication: Paracetamol	1.2	1.8	5.5	-1.2	-0.7	1.0	-1.5	-0.5	-2.4	-1.4	-1.5	-1.8	-1.3	-1.1	-1.2	-1.2	-1.8	-0.3
Alcohol drinker status: Never	1.2	1.4	2.8	1.6	0.9	1.6	1.3	1.5	1.4	-0.1	1.3	1.2	1.7	0.9	1.3	0.5	0.3	1.1
Supplements: Calcium	1.2	1.3	3.3	-1.2	-0.7	-1.1	-1.4	-1.4	-1.8	-0.1	-1.7	-1.5	-1.0	-1.1	-1.0	1.3	-0.2	0.1
Schizophrenia vs Biploar Disorder	1.1	1.4	4.3	1.8	2.1	-0.6	1.0	0.0	0.0	1.3	0.9	0.5	1.7	1.7	1.9	0.0	0.0	0.0
Reaction Time	1.1	2.1	8.8	-1.2	-1.9	0.0	-1.8	0.1	-1.1	-1.4	-0.7	-1.7	-1.8	-0.8	-0.7	-3.0	-1.6	-1.0
Coronary Artery Disease (CAD)	1.1	1.4	3.5	1.6	1.3	-0.4	1.5	0.0	1.2	1.3	1.5	1.4	1.0	1.3	1.9	0.0	0.0	0.0
Triglycerides	1.1	1.8	9.0	-1.2	0.6	0.2	-0.9	-1.8	-0.0	-0.3	-1.9	-1.4	-0.8	-1.3	-1.3	3.0	-0.3	-1.6
Type 2 Diabetes (T2D) (2018)	1.1	2.0	18.6	0.7	-0.5	-0.8	0.5	-1.4	0.4	1.0	0.3	0.4	1.4	-0.1	0.1	1.8	1.3	4.3
Fed-up feelings	1.1	2.0	5.5	-1.2	-1.5	2.4	-1.3	1.2	-1.1	-2.2	-1.5	-1.3	-0.8	-1.8	-0.6	0.4	-1.9	0.5
Hayfever, allergic rhinitis or eczema	1.1	2.4	13.5	1.1	0.9	-1.7	1.1	0.9	-0.2	0.6	1.6	1.4	0.6	1.7	1.6	-3.7	1.8	-1.1
Frequency of tenseness / restlessness in last 2 weeks	1.1	1.8	4.6	-1.3	-1.5	-0.3	-1.6	-1.3	-1.0	-0.5	-1.5	-1.8	-1.3	-2.1	-1.4	-0.1	-1.2	-1.1
Hip circumference	1.1	4.7	11.3	2.4	2.2	1.1	2.5	3.4	1.7	2.1	3.0	2.6	2.2	2.7	2.5	-0.4	0.2	-0.3
Lung cancer (father)	1.1	1.3	4.9	1.3	1.7	0.4	1.4	1.1	1.0	0.1	0.6	0.9	1.4	1.0	0.9	2.2	1.0	-0.2
Exposure to tobacco smoke outside home	1.1	1.4	4.8	1.1	-0.7	-1.2	0.7	0.7	0.7	2.2	1.7	1.4	0.8	1.4	-0.1	-1.6	1.4	0.8
Friendships satisfaction	1.1	1.4	2.7	-1.5	-1.1	-0.4	-1.3	0.3	-1.2	-0.3	-1.1	-1.2	-1.5	-1.3	-1.2	-1.4	-1.2	-1.6
Eye problems/disorders: Cataract	1.1	1.2	4.2	-1.0	-0.6	-0.1	-1.1	1.2	-0.9	-0.2	-0.2	-0.9	-1.6	-1.5	-1.0	-2.0	-1.4	-0.5
Pain type(s) experienced in last month: Hip pain	1.1	1.4	9.6	-0.6	-0.3	-0.7	-1.1	-0.0	-1.7	0.8	-0.2	-1.0	-1.1	-0.3	-0.2	-3.1	-1.2	-1.5
Supplements: Fish oil (including cod liver oil)	1.1	1.4	3.6	1.4	1.0	-1.4	1.0	1.9	0.9	1.1	1.2	1.0	0.8	1.1	1.6	-1.0	1.2	0.0
Deep venous thrombosis (DVT) (self-reported)	1.1	1.4	2.6	-1.4	-0.3	-0.0	-1.3	1.0	-1.3	-1.4	-0.7	-1.5	-1.6	-1.6	-1.5	-0.7	-1.4	-0.5
Depressed Affect (Nagel 2018)	1.0	2.2	6.1	-1.5	-1.9	2.5	-1.4	-0.2	-1.6	-2.1	-1.2	-1.3	-0.9	-1.7	-0.8	-0.5	-1.9	1.0
Irritable Bowel Disease (IBD)	1.0	2.4	6.2	-2.0	-2.0	-1.7	-1.9	0.1	-1.6	-0.6	-1.3	-1.6	-1.9	-1.4	-2.5	-0.8	-1.0	-0.8
Type 2 Diabetes (T2D) (2012)	1.0	1.1	2.9	-1.4	-0.8	0.6	-1.3	0.0	-1.1	-1.7	-1.0	-1.3	-1.4	-0.3	-0.4	0.0	-1.2	-1.1
Average weekly fortified wine intake	1.0	1.1	5.5	0.8	1.0	0.3	0.8	1.0	-0.1	1.3	0.8	0.7	0.4	2.4	1.5	-1.4	0.3	-0.8
Weight	1.0	5.1	10.5	2.6	3.0	1.0	2.6	3.2	1.9	1.9	2.6	2.6	2.4	2.8	2.6	0.4	0.8	-0.5
Time employed in main current job	1.0	1.2	3.1	-1.2	-0.9	-0.9	-1.0	-0.9	-1.2	-0.2	-0.5	-0.8	-1.6	-1.0	-1.2	-1.8	-1.2	-0.6
Medication: Cholesterol lowering	1.0	1.5	5.0	1.4	0.8	-1.2	1.1	0.0	0.3	2.2	0.6	0.8	1.5	1.1	0.9	1.0	2.0	1.6
Exposure to tobacco smoke at home	1.0	1.1	3.4	-0.9	-0.7	-0.3	-1.5	-1.6	-1.4	0.3	-1.3	-1.8	-0.8	-0.6	-1.0	0.5	-1.4	0.1
Number of children fathered	1.0	1.2	5.7	-0.4	-0.3	1.4	-0.2	-0.7	0.1	-1.7	-1.0	-0.5	-0.2	-2.0	-0.7	2.4	-0.2	0.7
Mood swings	1.0	1.7	4.0	-1.5	-1.3	1.3	-1.4	0.1	-2.0	-1.6	-1.2	-1.5	-1.2	-1.3	-0.4	-1.3	-1.9	0.4
Primary Biliary Cirrhosis	0.9	1.3	6.0	-0.9	-1.2	-0.6	-0.6	2.2	0.6	-2.4	-0.6	-0.3	-1.5	-1.1	-0.9	-0.7	-0.1	-0.7
Medication: Ramipril	0.9	1.2	4.0	-0.4	0.0	2.0	-0.8	-2.0	-1.8	0.7	-0.7	-1.1	0.1	-0.5	-0.9	0.4	-1.6	0.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.9	1.4	5.4	-0.7	-1.9	2.1	-0.9	-1.7	0.2	-0.4	-0.3	-0.6	-0.7	-0.9	-0.5	-0.9	-2.3	-0.1
Gout (self-reported)	0.9	1.2	4.0	0.9	0.3	-1.9	0.6	1.3	-0.2	2.0	0.8	0.5	0.9	1.3	0.7	-1.3	1.2	1.2
Medication: Allopurinol	0.9	1.3	5.1	0.5	-0.6	-2.2	0.1	1.6	0.1	2.2	0.8	0.3	0.3	0.5	-0.4	-1.5	1.3	0.6
Illnesses of father: None of the above (group 1)	0.9	1.1	3.1	1.3	1.8	-0.8	1.1	0.7	1.1	0.5	1.2	0.8	1.1	1.2	1.2	0.3	1.2	0.3
Diastolic blood pressure, automated reading	0.9	2.8	6.9	1.8	2.5	0.1	1.9	1.8	0.6	0.7	1.7	1.5	1.0	1.8	2.6	-1.7	0.3	-2.3
Smoking Status	0.8	1.9	11.5	-1.4	-0.5	-0.8	-1.2	-1.4	-1.3	0.1	-0.8	-1.0	-1.9	0.7	-0.6	-1.5	-0.6	-3.4
Supplements: Zinc	0.8	0.9	5.6	-0.0	0.2	-2.4	-0.2	1.0	-0.6	2.1	-0.1	-0.4	-0.1	-0.1	-1.3	-0.3	0.4	-0.6
Prospective memory result	0.8	1.0	5.7	-0.7	-0.6	-1.4	-1.1	0.1	-1.4	2.4	0.2	-0.9	-0.2	-0.4	-1.2	-0.2	-0.1	0.7
Length of working week for main job	0.8	0.8	4.5	-0.4	0.6	-0.6	-0.5	-1.3	-1.7	2.1	-0.6	-0.8	0.0	0.5	-0.9	0.4	0.0	-0.6
Qualifications: O levels/GCSEs or equivalent	0.8	1.3	4.4	1.4	1.2	-0.6	1.2	0.2	1.1	1.0	0.9	1.3	1.2	1.4	0.8	0.7	2.1	-0.3
Pulse wave peak to peak time	0.8	1.0	4.2	-1.1	-1.4	-1.0	-0.7	0.9	0.4	0.0	-0.2	-0.3	-1.5	-1.3	-2.0	-0.5	-0.9	-0.3
Neck or shoulder pain in last month	0.8	1.2	2.8	-1.0	-0.2	0.7	-0.6	1.1	-1.0	0.5	-0.8	-0.8	-1.5	-1.3	-1.4	-1.0	-1.7	-1.5
Mean time to correctly identify matches	0.8	1.5	11.4	-0.8	-1.7	-0.2	-1.2	0.5	-0.4	-0.9	0.2	-1.0	-1.5	-0.1	-0.3	-3.4	-1.1	-0.7
Pulse rate, automated reading	0.8	2.6	9.0	1.9	1.0	0.1	1.8	3.0	1.9	0.4	1.8	1.7	1.5	1.4	2.5	-0.1	1.3	-0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	1.0	2.3	-1.1	-0.4	0.4	-1.2	-1.5	-1.4	-0.9	-1.2	-1.5	-1.2	-0.5	-0.2	-0.2	-0.9	-0.3
Average weekly champagne plus white wine intake	0.8	1.2	4.9	0.9	-0.6	-0.7	1.0	1.0	1.6	0.2	1.1	1.4	1.1	0.3	-0.1	0.4	1.2	2.2
Miserableness	0.8	1.4	5.0	-1.0	-2.2	0.8	-1.4	0.4	-1.0	-1.9	-1.2	-1.3	-0.7	-1.4	0.1	-0.1	-1.2	0.4
Wears glasses or contact lenses	0.8	0.9	4.8	0.0	-0.2	-0.6	-0.2	1.9	-1.0	0.7	0.1	0.1	-0.2	1.2	-0.4	-2.2	-0.2	-1.5
Age at First Birth	0.7	1.0	2.0	1.1	1.4	0.8	1.3	1.4	0.6	0.2	0.6	1.3	1.1	1.0	1.2	-0.9	0.5	-0.0
Mean Putamen Volume	0.7	0.8	2.8	0.8	1.7	-0.5	1.0	0.6	0.9	-0.1	0.5	0.9	0.6	0.3	0.1	0.4	1.6	1.4
Ever used hormone-replacement therapy (HRT)	0.7	0.9	2.1	-1.2	-0.1	-0.5	-1.2	-0.8	-0.9	0.3	-0.6	-1.3	-1.4	-0.7	-1.1	0.5	-1.0	-1.2
Diabetes (father)	0.7	0.8	4.3	-0.5	-2.1	-0.8	-0.0	1.6	1.0	-0.7	-0.0	0.5	-0.4	-0.6	0.8	0.5	0.7	1.1
Relative age voice broke	0.7	1.1	3.7	-0.9	-0.9	-0.2	-1.1	-1.9	0.1	-0.6	-0.5	-1.0	-1.6	-0.2	-1.0	-0.7	-1.2	-1.8
Diverticular disease/diverticulitis (self-reported)	0.7	0.8	4.4	-0.1	0.9	-2.1	0.4	-0.7	0.5	0.3	-0.1	0.1	0.1	-0.6	-0.2	1.4	1.8	0.8
Financial difficulties in last 2 years	0.7	0.9	2.7	-0.9	0.1	-0.7	-1.4	-0.9	-0.9	0.6	-0.7	-1.6	-1.1	-0.5	-0.3	-1.1	-1.2	-0.9
Allergy	0.7	1.7	16.6	-0.3	-0.5	0.8	-0.4	-0.7	0.6	0.4	-0.9	-0.5	0.5	-0.7	-1.2	4.1	-0.5	1.7
Pain all over the body in last month	0.7	0.7	2.3	-0.5	-0.3	0.8	-0.8	-0.8	-0.6	-1.5	-0.7	-1.0	-0.2	-1.1	0.4	0.6	-0.9	1.3
Diabetes (self-reported)	0.7	1.1	10.2	0.4	-0.3	-0.2	0.5	-0.9	0.8	0.5	0.6	0.5	0.9	-0.5	0.5	1.4	0.6	3.2
Medication for pain relief, constipation, heartburn	0.7	1.2	4.0	1.2	1.1	-0.3	1.0	0.9	0.9	1.3	1.1	1.0	1.4	2.0	1.0	0.6	1.3	0.2
Knee pain experienced in last month	0.7	1.1	5.2	-0.7	0.2	0.0	-0.9	0.4	-1.5	-0.4	-0.8	-1.2	-1.0	0.2	0.4	-1.5	-1.4	-2.3
Average weekly red wine intake	0.7	1.1	5.2	-0.7	-1.7	-2.3	-0.3	-0.3	-0.2	-0.1	0.4	0.3	-0.9	-0.6	-1.2	-1.7	1.2	0.5
Diabetes diagnosed by doctor	0.7	1.2	13.0	0.5	-0.0	-0.1	0.7	-0.6	0.5	0.9	0.6	0.7	1.0	-0.4	0.5	0.7	0.6	3.6
Commuting to job workplace: Cycle	0.7	0.8	1.7	1.0	-0.7	-0.0	0.7	1.2	0.9	0.7	0.9	1.3	1.3	1.0	0.2	0.9	0.9	0.9
Bipolar Disorder (2018)	0.6	1.0	4.2	0.8	0.1	-0.0	1.4	0.0	2.0	-0.6	1.0	1.6	0.8	0.1	0.0	1.3	1.3	0.5
Eye problems/disorders: Diabetes related eye disease	0.6	0.7	1.7	0.5	0.2	-0.5	0.9	-0.1	1.3	0.1	1.1	1.2	0.3	-0.5	0.9	-1.0	0.9	1.0
Impedance of leg (right)	0.6	2.8	11.8	1.5	1.6	-0.7	1.5	0.1	1.5	1.4	1.2	1.3	2.0	-0.1	1.5	2.2	2.0	3.4
Current tobacco smoking	0.6	1.0	2.7	-0.9	-0.0	0.7	-1.3	-1.0	-1.3	-0.2	-1.2	-1.6	-0.9	0.0	0.3	-0.7	-1.0	-1.6
Maternal smoking around birth	0.6	0.9	3.9	-0.8	-0.6	0.3	-0.8	-2.0	-0.2	-0.5	-0.8	-0.8	-0.6	-1.8	-1.0	0.7	-0.6	-0.4
Supplements: Glucosamine	0.6	0.8	3.7	0.5	0.4	-0.2	-0.0	1.2	-1.7	1.0	0.1	-0.3	0.6	1.9	1.4	-0.5	0.1	0.0
Qualifications: None of the above	0.6	1.3	6.1	-0.8	-0.6	2.3	-1.0	0.1	-0.9	-0.9	-0.3	-1.4	-0.4	-1.1	-0.5	-0.6	-2.5	0.8
Heart attack	0.6	0.8	3.4	0.4	1.0	-0.0	0.4	-1.7	-0.3	0.8	-0.6	0.1	1.0	-0.8	-0.2	1.8	1.1	0.7
Impedance of arm (right)	0.6	2.7	13.7	1.4	0.8	0.6	1.5	-0.2	2.4	0.5	1.7	1.8	1.8	-0.8	0.8	1.7	1.3	3.7
Frequency of tiredness / lethargy in last 2 weeks	0.6	0.9	2.6	-0.8	-1.6	-1.0	-1.1	1.1	-0.8	-0.4	-0.7	-0.8	-1.0	-0.6	-1.2	-1.1	-0.6	-1.0
Qualifications: A levels/AS levels or equivalent	0.6	1.3	4.3	1.0	0.3	-1.9	0.9	1.0	1.0	1.1	0.9	1.1	0.8	1.3	0.9	-0.5	2.1	1.0
Depression (self-reported)	0.6	0.7	3.0	-0.5	-0.3	1.7	-0.7	-1.1	-0.5	-0.9	-0.7	-0.9	-0.3	-0.0	-0.0	-0.5	-1.5	-0.8
Pulse wave Arterial Stiffness index	0.6	0.8	3.1	0.9	1.2	1.0	0.5	-0.9	-0.4	-0.3	0.0	0.1	1.3	1.0	1.8	0.6	0.7	0.5
Impedance of arm (left)	0.6	2.6	13.4	1.4	0.9	0.4	1.5	0.6	2.1	0.5	1.5	1.8	1.8	-1.0	0.7	1.5	1.5	3.7
Birth weight of first child	0.6	1.1	6.2	0.8	1.2	0.1	0.9	0.2	1.1	1.4	0.1	0.8	1.3	0.3	0.2	2.5	0.9	0.6
Ever highly irritable/argumentative for 2 days	0.6	0.8	3.8	-0.9	-1.6	-0.3	-0.7	-0.0	-0.2	-0.1	0.1	-0.5	-1.3	-0.3	-0.8	-2.0	-1.1	-0.1
Medication for cholesterol, blood pressure or diabetes	0.6	1.0	4.4	-0.9	-0.9	0.9	-0.6	-0.1	1.0	-2.1	-0.3	-0.2	-1.0	-1.0	-0.4	-0.5	-1.4	-1.3
Medication: Ventolin 100micrograms inhaler	0.6	0.8	4.4	-0.8	0.1	-0.0	-0.6	-0.2	-1.2	0.2	-0.4	-0.8	-0.8	-0.6	-0.3	-2.1	-0.8	-1.5
Age at last live birth	0.6	0.8	4.4	0.8	0.7	-1.2	0.7	-0.0	0.5	2.1	0.7	0.8	1.0	0.8	-0.1	0.1	1.4	0.2
Illnesses of siblings: Diabetes	0.6	0.8	2.0	1.1	0.2	-0.6	0.8	-0.5	0.8	-0.0	1.1	0.9	1.0	1.0	1.0	0.8	0.8	1.4
Handedness (chirality/laterality): Left-handed	0.6	0.7	2.3	0.9	0.7	1.3	0.8	0.9	1.0	-0.3	0.8	0.5	0.9	0.2	0.8	0.4	-0.3	1.5
Medication: Gliclazide	0.6	0.7	6.8	0.2	-0.9	0.3	-0.1	0.7	0.8	0.5	1.0	0.3	0.3	-0.4	0.1	-0.3	-0.7	2.6
Mother’s age at death	0.6	0.8	2.0	0.6	-0.3	-1.0	0.7	1.3	1.4	0.8	1.3	1.1	0.1	-0.0	0.3	-1.1	0.7	1.0
High cholesterol (Self-reported)	0.6	1.1	5.6	0.6	0.2	1.9	0.3	-0.5	0.5	0.7	0.1	-0.1	0.9	-0.4	1.2	1.8	-0.0	2.4
Illnesses of father: High blood pressure	0.6	0.7	2.8	-0.8	-1.1	1.7	-0.5	0.6	-0.3	-0.2	-0.4	-0.3	-0.7	-0.9	-0.7	-0.6	-1.6	-0.4
Unable to work because of sickness or disability	0.6	0.7	3.4	1.0	0.4	0.6	0.5	1.2	1.2	0.2	1.2	0.3	0.5	0.6	1.8	0.2	-0.0	0.8
Medication: Omeprazole (e.g. Zanprol)	0.6	0.8	1.6	1.1	1.1	1.1	1.0	0.6	0.8	1.3	0.9	0.7	1.0	0.3	1.0	-0.5	0.6	0.2
Heart attack/myocardial infarction (self-reported)	0.6	0.7	3.5	0.2	0.7	-0.0	0.2	-1.9	-0.4	0.5	-0.7	-0.1	0.7	-1.0	-0.3	1.8	1.1	0.6
Impedance of whole body	0.6	3.1	15.4	1.6	1.1	0.0	1.6	0.4	2.3	0.5	1.5	1.8	2.0	-0.8	1.1	1.9	1.9	3.9
Schizophrenia (2018)	0.5	1.0	3.5	-0.6	-0.1	-1.8	-0.6	0.0	0.4	-0.8	-0.4	-0.5	-1.5	-0.7	-0.8	-1.9	0.3	-1.8
HDL Cholesterol	0.5	0.8	1.8	-0.9	-0.9	0.7	-0.9	-0.4	-1.3	-0.8	-1.2	-1.1	-0.5	-1.1	-0.6	0.6	-1.3	0.1
Ulcerative Colitis	0.5	0.8	1.9	-1.0	-1.2	-1.3	-0.8	0.0	-0.2	-1.3	-0.6	-0.5	-1.4	-0.6	-1.2	-0.8	-0.2	-0.2
Blood Eosinophil Count	0.5	4.2	8.4	1.8	1.0	-2.1	2.2	1.7	2.7	0.9	1.6	2.1	2.3	1.1	2.6	2.9	2.9	1.3
Respiratory disease	0.5	1.2	7.1	0.7	0.5	-0.9	0.8	0.9	-0.5	1.2	1.2	0.9	0.4	0.7	1.5	-2.7	0.1	-0.7
Chronotype (morning person)	0.5	1.1	4.3	-0.5	-2.0	-2.1	-0.2	0.3	0.3	1.7	0.2	0.4	0.1	-1.0	-0.8	-0.5	1.2	1.3
Angina	0.5	0.6	2.3	-0.8	0.4	0.1	-0.5	-0.7	-0.8	0.3	-1.5	-0.6	-0.4	-1.5	-1.2	0.4	0.4	-0.3
Medication: Metformin	0.5	0.7	6.5	-0.2	-1.0	0.3	-0.2	-0.6	-0.8	-0.5	0.2	-0.1	0.1	0.0	0.5	-0.8	-0.4	2.5
Diabetes (mother)	0.5	0.6	4.5	0.2	-0.1	2.1	0.2	0.3	-0.5	-0.7	-0.2	0.3	0.5	-0.3	0.9	0.4	-0.5	1.5
Pack years adult smoking proportion	0.5	0.8	2.4	-0.7	-0.4	-0.1	-1.1	-1.3	-0.8	0.5	-0.3	-1.3	-0.9	0.4	0.0	-1.0	-1.5	-1.2
Tinnitus: Yes, but not now, but have in the past	0.5	0.5	1.4	0.7	-0.3	0.3	0.6	0.7	0.8	1.2	0.7	0.7	0.7	0.9	0.4	-0.5	0.9	0.9
Stomach or abdominal pain in last month	0.5	0.6	3.0	-0.1	0.0	0.2	-0.2	1.1	0.2	-0.7	-0.3	-0.3	-0.7	-0.6	-0.0	-1.7	-0.8	-1.6
Medication: Atenolol	0.5	0.7	3.9	0.6	0.7	-0.6	0.7	0.6	-0.4	-0.5	0.7	0.5	0.8	0.8	0.9	-0.7	0.8	2.0
Impedance of leg (left)	0.5	2.6	10.2	1.4	1.2	-0.5	1.4	-0.1	2.0	1.1	1.1	1.2	1.9	-0.3	1.1	2.5	2.1	3.2
Past tobacco smoking	0.5	0.9	6.0	1.0	0.7	-0.0	0.7	1.1	0.2	-0.6	0.7	0.5	1.5	-0.4	0.9	0.5	0.4	2.4
Alcohol usually taken with meals	0.5	0.8	2.7	0.9	0.4	-0.5	0.9	1.6	0.6	0.8	0.9	1.2	1.1	0.3	-0.4	0.1	1.4	1.0
Had menopause	0.5	0.6	2.0	-0.1	1.3	-0.8	0.4	0.4	0.4	1.4	0.7	0.1	-0.0	0.9	0.2	1.2	0.2	-0.8
Falls in the last year	0.5	0.6	2.2	0.8	0.1	0.0	0.3	0.7	0.2	0.9	0.9	0.3	0.6	1.4	1.5	-1.4	-0.4	0.1
Hypothyroidism/myxoedema (self-reported)	0.5	0.9	2.6	-0.7	-1.3	0.5	-1.0	-1.6	-0.8	-1.6	-0.9	-0.8	-0.8	0.3	-0.2	0.2	-1.3	-1.2
Medication: Amlodipine	0.5	0.7	4.3	0.0	-0.3	2.1	-0.3	0.3	-1.3	0.3	0.5	-0.4	0.2	-0.3	0.8	0.1	-1.7	0.3
Comparative body size at age 10	0.5	1.4	6.0	0.9	0.0	-0.6	1.0	2.5	2.3	0.5	1.4	1.5	0.6	0.7	0.9	-0.2	1.2	-0.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.6	2.4	0.5	0.2	-0.1	0.6	1.4	0.8	0.7	0.8	0.6	0.6	0.4	1.3	0.4	-0.3	1.6
Angina (self-reported)	0.5	0.7	2.3	-0.8	0.5	0.2	-0.5	-1.0	-0.6	0.2	-1.5	-0.7	-0.5	-1.4	-1.2	0.9	0.3	-0.4
Smoking status: Previous	0.5	0.8	3.3	-1.1	-1.0	0.2	-0.8	-1.2	-0.6	0.3	-0.7	-0.4	-1.3	0.1	-0.8	-0.6	-0.6	-1.8
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.6	2.7	-0.7	0.2	0.3	-0.8	-1.6	-1.2	-0.1	-1.0	-1.0	-0.2	-0.3	-0.3	0.1	-0.4	0.6
Mineral and other dietary supplements	0.5	0.6	2.1	-0.3	-0.5	1.4	0.2	-1.3	0.9	-0.6	0.0	0.4	0.1	-1.0	-1.0	1.4	-0.4	0.4
Asthma (self-reported)	0.5	0.9	3.8	1.0	0.7	-0.0	0.8	1.1	-0.4	1.1	1.3	0.5	0.7	0.8	1.9	-1.1	0.1	0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.1	2.6	1.4	1.5	1.0	1.2	0.5	0.2	1.0	0.4	1.0	1.6	1.0	0.7	1.4	0.8	1.2
Medication: Blood pressure	0.5	1.0	8.1	0.3	0.1	2.8	0.0	-1.3	0.5	-0.5	0.6	-0.1	0.8	0.0	0.4	1.3	-1.1	1.1
Alcohol drinker status: Previous	0.5	0.5	2.2	-0.5	-1.5	-1.4	-0.9	-0.3	0.8	0.6	0.4	-0.7	-0.8	-0.3	-0.3	-0.5	-0.2	0.3
Ulcerative Colitis (UC)	0.4	0.7	4.3	-0.6	-0.8	-2.1	-0.4	1.4	-0.3	-0.2	0.1	-0.1	-0.6	-0.2	-1.1	-1.3	0.1	0.2
HbA1C	0.4	0.5	2.3	0.2	1.5	-0.5	0.5	-0.2	-0.6	0.9	0.5	0.3	0.3	1.4	-0.0	0.3	0.3	-0.5
LDL Cholesterol	0.4	0.6	5.0	0.1	1.1	0.4	-0.1	-0.8	-0.2	0.3	-1.0	-0.4	0.5	0.6	-0.6	2.2	0.4	-0.3
Neuroticism (2016)	0.4	0.5	1.9	0.2	-1.2	0.9	-0.1	0.3	0.9	-1.4	0.3	0.1	0.2	-0.7	0.1	0.7	-0.3	1.1
Schizophrenia (2014)	0.4	0.9	5.2	0.6	1.0	-2.3	0.6	0.0	1.3	0.3	0.7	0.6	0.0	-0.0	0.5	-1.4	1.4	-0.3
Hand grip strength (left)	0.4	0.9	3.6	1.1	1.9	-1.1	1.0	1.3	0.7	0.7	0.5	0.7	0.8	1.0	0.3	0.6	1.2	0.1
Number of treatments/medications taken	0.4	0.8	2.5	-0.7	-0.5	-0.0	-1.1	-0.3	-1.6	-0.2	-0.9	-1.5	-0.9	-1.3	-0.5	-0.4	-1.1	-0.2
Average weekly spirits intake	0.4	0.6	1.8	0.3	-0.1	1.3	0.7	0.9	1.3	-0.2	0.6	0.9	0.3	0.7	0.6	-0.4	0.1	1.2
Ever had hysterectomy (womb removed)	0.4	0.5	1.5	-0.4	0.8	-0.1	0.1	0.7	0.3	-0.9	0.3	-0.0	-0.9	0.5	1.2	-1.1	-0.6	-0.9
Systolic blood pressure, automated reading	0.4	1.0	5.4	0.0	1.4	0.4	-0.1	-0.3	-1.4	0.3	0.2	-0.5	-0.3	0.6	1.0	-1.8	-0.9	-2.3
Multivitamins +/- minerals	0.4	0.5	2.0	0.1	0.2	-1.4	-0.3	0.7	-0.0	1.1	-0.5	-0.3	0.0	0.6	0.4	0.1	0.7	-1.1
High blood pressure (mother)	0.4	0.6	2.3	0.5	1.5	-1.3	0.5	0.0	-0.0	0.5	0.4	0.3	0.2	1.4	0.7	-0.2	0.3	-0.9
Hearing difficulty/problems with background noise	0.4	0.6	3.9	0.1	-0.2	1.1	0.6	0.8	0.1	-0.6	0.5	0.6	-0.2	0.2	1.2	-2.0	-0.7	0.8
Hair/balding pattern: Pattern 3	0.4	0.7	3.0	0.7	0.6	-1.0	0.3	0.5	-0.5	1.7	0.5	0.1	1.0	0.8	0.9	0.7	0.8	1.0
Asthma	0.4	0.9	3.7	0.9	0.6	-0.1	0.7	1.2	-0.2	0.9	1.4	0.5	0.4	0.7	1.9	-1.5	-0.1	0.4
Illnesses of mother	0.4	0.6	2.6	-0.2	-0.8	0.9	-0.4	-0.6	1.1	-0.4	0.4	-0.2	0.2	-1.6	0.1	0.6	-0.5	1.2
Breastfed as a baby	0.4	0.5	3.0	0.0	0.3	-1.7	-0.1	0.5	-0.6	1.0	-0.1	0.0	0.1	0.5	-1.1	-0.5	1.0	0.0
Birth weight	0.4	0.9	6.1	0.8	0.6	-2.5	0.6	-0.3	0.1	0.8	0.4	0.6	0.7	0.9	0.5	0.9	1.4	-0.3
Heart disease (mother)	0.4	0.5	2.1	-0.0	-0.1	0.5	-0.0	1.2	-0.9	1.4	-0.9	-0.0	0.2	-0.5	-0.8	0.9	0.2	-0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	2.0	-0.4	0.3	-0.1	-0.8	-1.4	-0.5	-0.0	-0.5	-1.1	0.0	-0.3	-0.3	1.4	-0.5	0.4
Medication: Aspirin	0.4	0.5	1.6	0.7	0.4	-1.1	0.8	0.1	0.9	0.4	0.7	0.7	0.6	-0.1	0.5	0.4	0.8	1.3
Loneliness, isolation	0.4	0.5	2.5	-0.5	-0.9	0.5	-0.6	0.7	-0.4	0.3	-0.5	-0.6	0.1	-0.6	-0.7	0.9	-0.7	1.6
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	2.1	0.6	0.6	0.3	0.6	1.4	1.3	0.8	1.3	0.4	0.1	0.2	0.8	1.0	-0.5	-0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	1.4	-0.7	-0.6	-0.5	-0.8	-0.6	-0.6	0.1	-1.0	-0.9	-0.3	-1.2	-0.8	0.5	-0.2	1.1
Medication: Aspirin	0.4	0.5	2.0	0.6	0.3	-1.3	0.5	-0.2	0.5	1.0	0.6	0.4	0.7	-0.3	0.1	0.5	0.7	1.4
Smoking status: Current	0.4	0.7	3.1	-0.7	0.1	0.4	-0.9	-1.0	-0.8	0.2	-0.7	-1.2	-0.8	0.3	0.2	-0.7	-0.8	-1.8
Hearing aid user	0.4	0.4	1.9	0.4	0.7	0.6	0.8	0.5	1.2	-0.5	0.0	0.5	0.1	-0.3	-0.1	1.4	0.3	0.1
Irritability	0.4	0.8	4.5	-0.7	-2.1	0.9	-0.7	-0.7	0.3	-1.6	-0.5	-0.3	-0.7	-0.7	-0.3	-0.2	-0.8	0.0
Heart disease (siblings)	0.4	0.6	1.4	-0.4	0.6	1.1	-0.2	-1.2	-1.0	-0.9	-0.7	-0.5	0.0	-1.2	0.2	0.7	-0.4	-0.4
Pack years of smoking	0.4	0.6	1.5	-0.6	-0.3	-0.0	-0.9	-1.1	-0.7	0.6	-0.1	-1.0	-0.7	0.4	0.1	-1.0	-1.2	-1.0
Bipolar Disorder or Schizophrenia	0.3	0.7	2.6	0.0	-0.0	-1.4	0.4	0.0	1.6	-1.0	0.3	0.6	-0.7	-0.5	-0.7	-0.7	1.0	-1.1
Prostate Cancer	0.3	0.4	2.1	0.7	-0.3	-0.4	0.4	-0.4	1.0	-0.2	0.4	0.6	0.2	0.8	0.4	-0.5	0.7	-1.4
Systolic Blood Pressure	0.3	1.7	3.6	-1.2	-0.1	0.7	-1.3	-1.6	-1.7	-0.9	-0.6	-1.6	-1.4	-1.1	-0.8	-1.6	-1.9	-1.9
Cardiovascular Disease	0.3	1.1	4.9	1.1	0.3	2.2	0.7	-0.4	1.2	0.8	1.4	0.6	1.4	0.3	1.0	0.7	-0.0	1.4
Sensitivity / hurt feelings	0.3	0.5	1.6	-0.6	-0.6	-0.3	-1.0	-0.1	-0.8	0.2	-0.7	-1.3	-0.5	-0.6	-0.6	-0.3	-1.0	0.5
Hearing difficulty/problems: Yes	0.3	0.4	2.0	-0.1	0.2	-0.2	0.5	1.4	0.2	-1.4	-0.0	0.6	-0.3	-0.9	-0.2	-0.6	0.3	0.2
Other serious medical condition/disability diagnosed by doctor	0.3	0.3	1.1	0.0	0.6	0.1	-0.1	1.0	0.0	-0.5	-1.0	-0.5	-0.5	-0.6	0.5	0.6	-0.1	-1.0
Vitamin and mineral supplements	0.3	0.5	1.7	0.2	0.3	1.3	0.9	-0.4	0.3	-0.5	1.2	1.1	0.2	0.1	0.1	-0.5	-0.6	0.6
Townsend deprivation index at recruitment	0.3	0.4	2.4	0.2	-0.4	-0.6	-0.0	0.9	0.5	0.3	0.7	0.1	-0.5	-0.5	0.9	-1.6	-0.5	-0.7
Taking other prescription medications	0.3	0.4	2.4	0.5	-0.1	0.1	0.4	1.3	-0.0	-0.3	0.8	0.4	-0.1	-0.1	0.8	-1.6	-0.4	-0.2
Bilateral oophorectomy (both ovaries removed)	0.3	0.4	1.7	0.2	1.3	-1.2	0.3	0.6	0.2	0.3	0.7	0.0	-0.3	0.2	1.2	-0.1	0.1	-0.0
Medication: Levothyroxine sodium	0.3	0.5	2.7	0.1	-0.6	1.6	-0.0	-0.5	0.1	-1.5	-0.2	0.1	0.4	0.8	0.8	0.5	-0.7	-0.0
Mouth/teeth dental problems	0.3	0.5	2.3	-0.4	-0.4	0.1	-0.6	-1.5	-0.6	-1.1	-1.0	-0.6	-0.3	-0.2	-1.1	-0.5	0.3	-0.4
Trunk fat-free mass	0.3	1.5	7.3	-1.2	-0.4	0.2	-1.0	1.6	-1.1	-1.0	-0.8	-1.0	-1.6	0.4	-0.9	-0.2	-1.4	-2.7
Forced expiratory volume in 1-second (FEV1)	0.3	1.1	6.9	0.9	0.9	-0.5	0.9	2.6	0.5	0.1	0.4	1.1	0.9	0.6	-0.1	1.1	1.4	1.0
Happiness	0.3	0.4	2.4	0.6	0.1	0.6	0.5	1.6	0.7	-0.7	0.5	0.5	0.6	0.0	0.4	-0.4	0.2	0.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	0.9	3.6	0.7	0.4	1.4	0.8	1.9	0.9	-0.6	0.3	1.0	0.8	-0.2	0.2	1.4	0.4	1.2
Trunk predicted mass	0.3	1.5	7.3	-1.2	-0.4	0.2	-1.0	1.6	-1.1	-1.0	-0.8	-1.0	-1.6	0.4	-1.0	-0.2	-1.4	-2.7
Peak expiratory flow (PEF)	0.3	0.7	2.2	1.0	0.9	-0.2	1.0	1.5	0.2	0.6	0.7	1.2	0.9	1.1	0.1	-0.0	1.2	0.5
Medication: Paracetamol	0.3	0.5	2.5	-0.3	-0.0	0.9	-0.6	0.1	-1.6	-0.4	-0.7	-0.8	-0.5	-0.3	-0.2	-0.8	-1.5	-0.2
Age at first live birth	0.3	0.5	2.0	0.5	-0.0	-0.6	0.6	0.1	1.2	1.4	0.1	0.8	0.6	0.1	-0.9	0.8	1.0	0.2
Shortness of breath walking on level ground	0.3	0.4	1.3	0.4	0.9	-0.1	0.1	-0.4	-0.9	1.1	0.1	-0.4	0.6	-0.2	0.9	0.4	-0.2	0.9
Medication: Blood pressure	0.3	0.5	4.3	-0.0	0.2	-0.7	-0.1	-0.2	-2.1	1.3	-0.3	-0.5	-0.0	0.1	-0.4	-0.3	0.1	-0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.6	7.0	-0.2	-0.4	0.4	0.2	2.6	0.9	-0.3	0.5	0.6	-0.4	-0.2	-0.5	0.3	0.1	0.0
Ever had bowel cancer screening	0.3	0.4	1.1	-0.5	0.2	0.7	-0.5	0.5	-0.3	-0.8	-0.4	-0.6	-0.8	-0.7	0.2	-0.8	-1.1	-0.4
Osteoarthritis (self-reported)	0.3	0.3	1.3	0.3	1.1	0.5	0.1	-0.0	-0.9	-0.1	0.0	-0.3	0.3	-0.6	0.8	-1.1	-0.6	0.2
Number of self-reported non-cancer illnesses	0.3	0.5	3.9	0.1	0.0	0.3	0.0	0.2	-0.6	-0.5	0.4	-0.1	-0.2	0.1	1.3	-2.0	-0.1	0.4
Ever taken oral contraceptive pill	0.3	0.3	1.6	0.2	-0.1	-0.7	0.2	-1.3	0.4	-0.0	0.2	0.4	0.3	0.3	0.1	1.0	0.8	0.5
Ever depressed for a whole week	0.3	0.4	1.6	-0.1	-1.2	0.1	-0.4	1.2	-0.9	0.4	-0.0	-0.4	-0.0	-0.1	0.3	-0.8	-0.8	0.8
Depression (Nagel 2018)	0.2	0.2	1.0	-0.1	-0.4	-0.2	-0.2	0.3	-0.6	-0.3	-0.5	-0.1	0.2	-0.6	-0.5	-1.0	0.6	0.8
Lupus	0.2	0.3	1.4	-0.6	-0.3	0.3	-0.3	0.6	0.2	-1.2	0.2	-0.2	-0.6	-0.2	0.3	-1.2	-0.7	-0.3
Hypothyroidism (self reported)	0.2	0.3	1.6	0.5	0.0	-0.0	-0.0	-0.6	-0.6	-0.3	-0.4	-0.1	0.8	1.0	0.7	1.3	0.2	-0.3
Lung FVC	0.2	1.0	4.0	-1.3	-0.8	0.2	-0.9	0.3	-0.2	-1.1	-1.4	-0.6	-1.4	-1.1	-2.0	-0.7	-0.5	-0.7
Tanning	0.2	2.6	6.7	-2.1	-2.2	-1.1	-1.4	-2.2	-1.1	-1.1	-1.8	-1.0	-1.8	-2.1	-2.6	-0.7	-0.3	0.0
Medication: Co-codamol	0.2	0.2	0.6	-0.1	0.5	-0.4	-0.1	0.1	-0.1	0.6	-0.1	-0.4	-0.5	0.2	0.5	0.4	-0.6	-0.8
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	1.0	0.0	0.1	0.1	-0.3	0.4	-1.0	1.0	-0.5	-0.4	0.6	-0.3	-0.7	-0.4	-0.2	0.4
Serious illness, injury or assault to yourself	0.2	0.3	0.7	0.1	0.1	0.8	-0.3	0.8	0.3	0.0	-0.0	-0.5	-0.2	-0.7	-0.9	-0.2	-0.9	-0.8
High blood pressure	0.2	0.5	2.9	0.6	0.1	1.7	0.3	-0.5	0.2	0.4	1.2	0.3	0.5	0.3	0.8	-0.7	-1.0	0.1
Sitting height	0.2	1.1	7.2	0.1	1.1	-1.6	0.7	2.7	0.4	-1.1	0.3	0.9	-0.5	0.3	-0.9	-0.3	1.2	-0.6
Leg predicted mass (left)	0.2	0.8	6.1	0.3	0.7	0.6	0.5	2.5	0.2	0.1	0.7	0.6	0.0	1.0	0.2	-0.2	-0.6	-1.6
Hair/balding pattern: Pattern 2	0.2	0.3	2.0	-0.3	-0.3	0.4	-0.2	-0.1	-0.4	-0.5	-0.4	-0.2	-0.4	-0.1	-0.2	-0.7	-0.4	-1.4
Forced vital capacity (FVC)	0.2	0.8	6.4	-0.1	0.3	-1.5	0.1	2.5	0.1	-0.4	-0.2	0.4	-0.3	-0.5	-0.9	0.4	1.1	0.8
Ever unenthusiastic/disinterested for a whole week	0.2	0.3	1.2	0.3	-0.9	-0.8	-0.3	0.5	-0.6	0.6	0.0	-0.2	0.1	0.8	0.3	-1.1	0.2	0.2
Alcohol intake versus 10 years previously	0.2	0.2	0.8	0.1	-0.2	-0.9	0.3	0.6	0.1	0.2	0.4	0.4	0.1	0.2	0.9	-0.3	0.6	-0.7
Noisy workplace	0.2	0.3	0.9	-0.5	-0.1	-0.3	-0.4	-0.2	-0.9	0.6	0.1	-0.6	-0.4	-0.6	-0.0	-1.0	-0.8	0.5
Mouth/teeth dental problems: Dentures	0.2	0.3	0.8	0.4	0.7	0.8	0.5	0.2	-0.1	0.9	0.3	0.4	0.4	0.5	0.5	0.9	-0.2	0.1
Forced vital capacity (FVC), Best measure	0.2	0.6	2.2	-0.3	-0.2	0.9	-0.0	1.5	0.3	-1.1	-0.4	0.2	-0.3	-1.2	-0.6	0.9	0.0	0.8
Arm fat-free mass (right)	0.2	0.9	6.2	-0.2	0.2	-0.2	-0.2	2.5	-0.5	-0.1	-0.0	-0.3	-0.6	1.2	0.2	-0.3	-0.6	-2.2
Number of full brothers	0.2	0.3	1.3	-0.0	-0.2	-0.0	-0.3	-0.3	-0.1	0.7	0.1	-0.3	0.7	-0.7	-1.1	0.5	0.6	0.9
Wheeze or whistling in the chest in last year	0.2	0.4	2.1	-0.4	-0.4	-0.0	-0.3	-0.1	-1.5	1.0	0.3	-0.3	-0.0	-0.2	0.1	-1.3	-0.5	0.6
Mouth/teeth dental problems: Loose teeth	0.2	0.2	1.1	0.3	-0.1	0.6	-0.2	1.1	-0.2	0.8	0.0	-0.2	0.1	0.5	0.4	0.4	-0.4	0.1
Arm predicted mass (right)	0.2	0.9	5.4	-0.2	0.5	-0.1	-0.1	2.3	-0.5	-0.0	-0.1	-0.2	-0.5	1.3	0.1	-0.2	-0.5	-2.3
Comparative height size at age 10	0.2	1.0	7.1	-0.2	0.0	-0.7	-0.2	2.7	0.3	-1.7	0.2	0.1	-1.0	0.7	0.5	-0.7	-0.3	-1.5
Hypertension (Self-reported)	0.2	0.5	3.0	0.2	0.2	1.7	-0.1	-1.4	-0.3	0.3	0.5	-0.3	0.2	0.1	0.5	-0.3	-1.3	-0.4
Illnesses of father: Heart disease	0.2	0.3	1.3	0.3	0.2	1.1	0.6	-0.4	0.8	-0.2	0.0	0.6	0.1	-0.2	0.4	-0.0	-0.0	0.8
Whole body fat-free mass	0.2	0.9	5.6	-0.6	0.0	0.4	-0.4	2.0	-0.5	-0.6	-0.2	-0.4	-1.0	0.7	-0.5	-0.3	-1.1	-2.4
Long-standing illness, disability or infirmity	0.2	0.4	1.6	-0.0	0.2	0.2	-0.3	0.8	-0.1	-1.3	-0.5	-0.6	-0.3	-0.9	0.4	-0.3	-0.6	-0.8
Breast cancer (self-reported)	0.2	0.3	1.4	-0.2	0.1	0.6	-0.2	-0.2	-0.7	0.4	-0.1	-0.0	-0.5	0.1	-0.7	-0.8	-0.5	-1.2
Whole body water mass	0.2	0.9	5.4	-0.5	0.1	0.5	-0.3	2.0	-0.6	-0.5	-0.2	-0.3	-0.9	0.8	-0.4	-0.2	-1.1	-2.3
Tinnitus: Yes, now most or all of the time	0.2	0.2	1.0	0.5	0.3	-0.3	0.5	1.0	0.2	-0.2	0.5	0.6	0.4	0.2	0.0	0.0	0.3	0.6
Medication: Bendroflumethiazide	0.2	0.3	2.2	-0.3	0.4	0.6	-0.2	-0.2	0.0	-0.2	-0.3	-0.3	-0.1	0.4	-0.2	1.0	-0.5	-1.5
Basal metabolic rate	0.2	0.9	6.0	0.2	0.8	0.6	0.4	2.4	0.1	0.1	0.4	0.4	-0.1	1.3	0.2	0.1	-0.6	-2.0
Arm fat-free mass (left)	0.2	0.9	4.8	0.1	0.7	0.7	0.1	2.1	-0.1	-0.4	0.1	0.0	-0.3	1.5	0.7	-0.1	-0.8	-2.2
Risk taking	0.2	0.3	1.8	-0.1	-0.5	-0.4	-0.3	-1.4	-0.3	0.7	-0.0	-0.3	-0.2	0.2	0.7	-0.4	-0.1	-0.2
Myopia	0.2	0.3	2.3	0.2	0.3	0.2	0.4	1.5	-0.2	0.5	-0.2	0.5	0.2	0.4	-0.0	0.8	0.5	0.4
Vascular/heart problems diagnosed by doctor	0.2	0.4	1.4	-0.6	-0.7	-1.2	-0.5	0.8	-0.1	-0.7	-1.1	-0.3	-0.6	-0.4	-0.9	0.5	0.6	-0.0
Arm predicted mass (left)	0.2	0.9	4.8	-0.1	0.5	0.6	-0.0	2.0	-0.3	-0.2	0.1	-0.2	-0.4	1.4	0.5	-0.1	-0.9	-2.2
Major Depression (MDD)	0.1	0.1	0.6	0.6	0.2	-0.1	-0.0	0.0	-0.5	0.7	-0.0	-0.0	0.8	0.5	0.3	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	0.1	0.2	1.0	0.1	0.2	0.2	0.3	-0.8	0.3	0.5	0.6	0.2	0.1	-0.1	-0.3	1.0	-0.6	-0.0
Height	0.1	1.8	12.5	-1.0	1.2	-1.0	-0.5	3.5	0.3	-1.5	-0.3	-0.7	-1.5	-0.3	-0.9	2.0	0.1	-1.3
Leg fat-free mass (left)	0.1	0.8	6.1	0.2	0.6	0.6	0.4	2.5	0.1	0.1	0.6	0.6	-0.0	1.0	0.1	-0.2	-0.7	-1.6
Hand grip strength (right)	0.1	0.4	2.6	0.3	1.6	-0.2	0.5	1.2	-0.3	0.4	-0.0	0.2	0.3	0.1	-0.7	0.3	0.2	-0.4
Number of live births	0.1	0.2	1.2	0.3	0.2	-0.0	0.2	-0.7	0.1	-0.3	0.8	0.0	0.3	0.4	1.1	0.3	0.1	0.4
Pulse rate	0.1	0.2	0.9	0.1	0.1	-0.6	-0.1	0.5	-0.4	0.7	-0.5	-0.2	-0.2	-0.3	1.0	-0.2	0.0	-0.7
Standing height	0.1	1.1	7.0	-0.8	0.2	-0.9	-0.2	2.6	0.3	-1.4	-0.1	0.0	-1.0	-1.0	-1.3	1.5	0.5	0.2
Leg fat-free mass (right)	0.1	0.8	5.1	-0.1	0.2	0.5	0.1	2.2	0.2	-0.2	0.3	0.3	-0.5	0.8	-0.3	-0.3	-0.7	-2.1
Qualifications: nursing, teaching	0.1	0.2	0.6	0.2	-0.0	-0.8	0.5	-0.1	0.8	0.7	0.2	0.7	0.3	-0.0	-0.3	-0.2	0.7	-0.2
Leg predicted mass (right)	0.1	0.8	4.9	-0.1	0.2	0.5	0.1	2.2	0.2	-0.2	0.3	0.3	-0.5	0.8	-0.4	-0.2	-0.7	-2.1
Medication: Lisinopril	0.1	0.2	1.0	-0.0	-0.3	-0.4	-0.0	0.8	0.3	-0.3	0.3	-0.2	-0.3	-0.2	-0.4	1.0	-0.3	-0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Blood Platelet Count	0.0	0.5	4.2	-0.1	-1.1	0.4	-0.0	0.0	-0.2	-0.6	0.2	0.6	-0.0	0.6	-0.1	-2.1	0.1	-0.3
Hair Pigment	0.0	0.8	7.0	0.3	0.7	-1.4	0.2	2.6	0.1	0.1	1.1	0.2	-0.3	0.8	0.3	-0.7	0.1	0.8

Hub : Genes

CPLX1

Models

Trait associations