Best TWAS P=6.81e-09 · Best GWAS P=6.24e-12 conditioned to 0.0188
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Stomach | HOTAIRM1 | 0.14 | 0.12 | lasso | 5 | 0.15 | 8.8e-08 | 5.2 | 5.5 | 3.0e-08 | 0.77 | 0.05 | 0.92 | FALSE |
2 | YFS | Blood | HOXA9 | 0.06 | 0.05 | lasso | 6 | 0.06 | 2.0e-19 | 6.9 | -5.4 | 5.5e-08 | -0.88 | 0.00 | 1.00 | FALSE |
3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | HOXA10 | 0.02 | 0.01 | blup | 53 | 0.01 | 9.0e-03 | 6.3 | -5.2 | 2.3e-07 | -0.13 | 0.02 | 0.36 | TRUE |
4 | The Cancer Genome Atlas | Thyroid Carcinoma | HOXA9 | 0.04 | 0.04 | lasso | 2 | 0.04 | 1.4e-04 | 5.7 | -5.8 | 6.8e-09 | -0.91 | 0.01 | 0.98 | TRUE |