TWAS hub - HOXA9

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	YFS	Blood	0.0649	0.0168	3.7e-13	0.045	0.052	0.058	0.057	0.062	1.4e-14	1.2e-16	2.4e-18	4.4e-18	2.0e-19
2	TCGA	Thyroid Carcinoma	0.0440	0.0240	5.5e-04	0.037	0.023	0.028	NA	0.038	1.6e-04	2.2e-03	8.0e-04	NA	1.3e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Arm fat percentage (right)	11.0	43.4	44.2	-6.5	-6.7
Waist Hip Ratio (WHR)	10.7	48.2	72.6	8.5	4.9
Arm fat percentage (left)	9.8	38.9	40.7	-6.1	-6.4
Trunk fat percentage	8.1	32.3	35.0	-5.4	-5.9
Body fat percentage	8.0	31.6	33.6	-5.4	-5.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	7.4	8.7	9.2	2.8	3.0
Ulcerative Colitis (UC)	6.1	11.4	11.5	-3.4	-3.4
Body Mass Index (BMI) (2010)	6.1	8.3	8.6	-2.8	-2.9
Birth weight of first child	6.1	11.1	14.0	3.7	2.9
Arm fat mass (right)	6.0	24.8	25.9	-4.9	-5.1
Arm fat mass (left)	5.4	22.3	23.8	-4.6	-4.9
Ever had prostate specific antigen (PSA) test	5.4	6.2	6.8	-2.4	-2.6
Trunk fat mass	5.3	22.7	26.2	-4.4	-5.1
Mouth/teeth dental problems: Loose teeth	5.2	6.2	7.4	2.7	2.2
Comparative body size at age 10	5.0	13.8	15.0	-3.6	-3.9
Whole body fat mass	5.0	20.8	23.1	-4.3	-4.8
Leg fat percentage (left)	4.9	17.6	18.4	-4.1	-4.3
Irritable Bowel Disease (IBD)	4.8	11.3	12.0	-3.5	-3.3
Leg fat percentage (right)	4.5	16.2	17.8	-3.8	-4.2
Had other major operations	4.2	5.1	5.5	2.3	2.2
Leg fat mass (right)	3.9	14.9	17.4	-3.5	-4.2
Leg fat mass (left)	3.9	15.2	17.2	-3.6	-4.1
Ever had stillbirth, spontaneous miscarriage or termination	3.7	4.0	4.2	2.0	1.9
Breast cancer (self-reported)	3.6	4.3	6.4	-1.5	-2.5
Body mass index (BMI)	3.5	15.0	15.9	-4.0	-3.8
Supplements: Calcium	3.4	3.7	3.8	1.9	2.0
Hip circumference	3.3	14.2	17.7	-4.2	-3.3
Age when periods started (menarche)	3.2	7.6	10.6	2.1	3.3
Heel bone mineral density (BMD) T-score, automated (left)	3.2	7.3	13.9	-0.9	-3.7
Medication for pain relief, constipation, heartburn	3.2	5.5	7.0	-2.0	-2.7
Breast Cancer	3.1	7.5	8.0	2.6	2.8
BMI	3.0	17.3	22.6	-4.8	-3.5
Tinnitus: Yes, but not now, but have in the past	2.9	3.1	3.1	1.8	1.7
Hearing difficulty/problems: Yes	2.7	4.1	5.1	2.3	1.8
Heel bone mineral density (BMD) T-score, automated (right)	2.7	6.3	12.5	-0.2	-3.5
Coronary Artery Disease (CAD)	2.6	3.2	3.8	2.0	1.6
Alcohol intake frequency.	2.6	6.2	6.4	2.4	2.5
Number of operations (self-reported)	2.6	3.8	5.8	2.4	1.4
Length of working week for main job	2.5	2.8	3.7	1.9	1.4
Ever used hormone-replacement therapy (HRT)	2.4	3.0	3.7	1.9	1.5
High blood pressure (siblings)	2.4	3.5	6.0	-2.5	-1.0
Crohns Disease (2017)	2.3	5.0	5.9	-2.4	-2.0
Heel T-Score	2.3	18.1	35.5	-0.8	-6.0
Impedance of arm (right)	2.3	10.8	11.7	-3.2	-3.4
Exposure to tobacco smoke at home	2.3	2.6	3.3	1.8	1.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.3	2.7	4.2	-1.1	-2.0
Illnesses of father: High blood pressure	2.1	2.5	2.9	-1.7	-1.5
Medication: Gliclazide	2.0	2.2	2.8	1.7	1.3
Impedance of arm (left)	1.8	8.4	10.2	-2.6	-3.2
Diastolic blood pressure, automated reading	1.8	5.6	8.5	-2.9	-1.7
Ulcerative Colitis	1.7	2.4	3.3	-1.2	-1.8
Suffer from ‘nerves’	1.7	2.7	3.5	1.9	1.4
Crohns Disease (2012)	1.6	2.7	2.8	-1.6	-1.7
Severe depression (siblings)	1.6	1.8	2.3	-1.1	-1.5
Hand grip strength (right)	1.6	4.5	7.1	-1.4	-2.7
Forced expiratory volume in 1-second (FEV1), predicted	1.6	3.3	4.4	2.1	1.5
Blood Red Count	1.5	14.3	15.1	3.9	3.7
Medication for hormone replacement therapy	1.5	1.7	3.4	1.8	-0.0
Weight	1.5	7.5	9.1	-2.5	-3.0
Medication: Omeprazole	1.5	1.8	2.2	1.2	1.5
Commuting to job workplace: Cycle	1.5	1.8	2.1	1.2	1.5
Heart attack	1.4	1.7	2.0	1.4	1.2
Eye problems/disorders: None of the above	1.4	1.6	1.6	1.3	1.3
Heart disease (siblings)	1.4	1.7	1.9	1.2	1.4
Hair/balding pattern: Pattern 2	1.3	1.6	2.5	1.6	0.8
Father’s age at death	1.3	1.7	1.7	-1.3	-1.3
Medication: Paracetamol	1.3	2.2	2.2	1.5	1.5
Number of full brothers	1.3	1.7	1.8	1.3	1.3
Medication: Omeprazole (e.g. Zanprol)	1.3	1.6	1.8	1.1	1.4
Average weekly fortified wine intake	1.2	1.4	2.3	0.7	1.5
Pain all over the body in last month	1.2	1.3	2.2	0.5	1.5
Falls in the last year	1.2	1.6	2.4	-1.6	0.9
Commuting to job workplace: Car/motor vehicle	1.2	1.3	1.7	1.3	1.0
Hearing aid user	1.2	1.4	1.8	1.4	0.9
Myopia	1.2	1.7	2.4	1.1	1.5
Heart attack/myocardial infarction (self-reported)	1.2	1.5	2.0	1.4	1.0
Alzheimer’s Disease (in father)	1.1	1.2	1.3	1.1	1.1
Type 2 Diabetes (T2D) (2012)	1.1	1.3	1.5	-1.2	-1.0
Alcohol usually taken with meals	1.1	1.8	2.9	-1.7	-0.9
Depression (self-reported)	1.1	1.3	1.9	1.4	0.9
Tense / ‘highly strung’	1.1	1.8	3.0	1.7	0.8
Pulse wave reflection index	1.1	1.4	2.2	-1.5	-0.8
Qualifications: College or University degree	1.1	3.6	5.6	-1.2	-2.4
Commuting to job workplace: Walk	1.1	1.2	1.3	1.1	1.1
Average weekly beer plus cider intake	1.1	1.6	1.6	1.3	1.2
Alzheimer’s Disease (including proxy)	1.0	1.5	1.6	1.2	1.3
Major Depression (MDD)	1.0	1.2	1.5	1.2	1.0
Average weekly champagne plus white wine intake	1.0	1.4	2.4	-1.6	-0.7
Medication: Paracetamol	1.0	1.5	2.0	1.0	1.4
Medication: Atorvastatin	1.0	1.2	1.5	-1.2	-1.0
Basal cell carcinoma (self-reported)	1.0	1.1	1.6	1.3	0.8
Primary Biliary Cirrhosis	0.9	1.3	1.4	-1.2	-1.0
Diabetes (mother)	0.9	1.2	1.2	-1.1	-1.1
Hearing difficulty/problems with background noise	0.9	1.5	1.5	1.2	1.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.9	1.4	2.4	1.5	0.6
Worry too long after embarrassment	0.9	1.5	2.0	-1.4	-1.0
Supplements: Vitamin C	0.9	1.0	1.4	1.2	0.8
Smoking status: Previous	0.9	1.4	1.6	-1.0	-1.3
Eye problems/disorders: Cataract	0.9	1.0	1.4	-1.2	-0.8
Back pain experienced in last month	0.9	1.3	1.6	-1.0	-1.3
Medication: Aspirin	0.9	1.2	1.2	1.1	1.1
Smoking status: Current	0.9	1.4	1.4	1.2	1.2
Wears glasses or contact lenses	0.9	1.0	1.5	-1.2	-0.7
Blood Platelet Count	0.8	8.9	15.8	1.4	4.0
Hand grip strength (left)	0.8	2.0	3.8	-0.5	-1.9
Serious illness, injury or assault of a close relative in last 2 years	0.8	1.0	1.4	-0.8	-1.2
Ever highly irritable/argumentative for 2 days	0.8	1.0	1.5	0.7	1.2
Medication: Ventolin 100micrograms inhaler	0.8	1.0	1.4	1.2	-0.7
Number of full sisters	0.8	1.0	1.6	-1.3	-0.6
Leg pain on walking	0.8	1.1	1.9	0.5	1.4
Pain type(s) experienced in last month: Hip pain	0.8	1.0	2.0	0.2	-1.4
Medication: Bendroflumethiazide	0.8	1.3	2.1	0.6	1.5
Medication: Lisinopril	0.8	1.1	1.5	-1.2	-0.8
Prostate Cancer	0.7	1.1	1.8	-1.3	0.6
Medication: Co-codamol	0.7	0.8	1.0	-1.0	-0.7
Diabetes (father)	0.7	0.9	1.4	1.2	0.6
Illnesses of siblings	0.7	1.0	2.0	1.4	-0.1
Noisy workplace	0.7	0.9	1.3	0.6	1.1
Prospective memory result	0.7	0.9	1.0	-1.0	-0.9
Forced expiratory volume in 1-second (FEV1), Best measure	0.7	2.3	3.5	1.1	1.9
Standing height	0.7	6.5	11.0	3.3	1.4
Hair/balding pattern: Pattern 4	0.7	1.6	2.6	1.6	0.8
Qualifications: O levels/GCSEs or equivalent	0.7	1.1	1.2	-1.0	-1.1
Arm predicted mass (right)	0.7	3.3	4.7	2.2	1.4
Medication: Aspirin	0.7	1.0	1.1	0.9	1.0
Average weekly red wine intake	0.7	1.0	1.1	0.9	1.1
High cholesterol (Self-reported)	0.7	1.3	1.9	-1.4	-0.8
Bipolar Disorder or Schizophrenia	0.6	1.3	1.8	-1.4	-0.9
Relative age of first facial hair	0.6	1.2	2.3	0.0	1.5
Impedance of leg (right)	0.6	2.7	3.8	1.9	1.3
Leg fat-free mass (left)	0.6	2.9	3.9	-1.4	-2.0
High blood pressure (mother)	0.6	0.8	0.8	-0.9	-0.9
Number of incorrect matches in round	0.6	0.9	0.9	-1.0	-0.9
Trunk fat-free mass	0.6	3.6	4.9	2.2	1.5
Forced expiratory volume in 1-second (FEV1)	0.6	2.1	3.2	1.0	1.8
Trunk predicted mass	0.6	3.6	5.0	2.2	1.5
Loud music exposure frequency	0.6	0.6	0.8	-0.7	-0.9
Blood clot in the leg (DVT)	0.6	0.8	1.3	1.2	0.6
Forced vital capacity (FVC), Best measure	0.6	2.2	2.2	1.5	1.5
Eye problems/disorders: Glaucoma	0.6	0.7	1.1	-1.1	-0.6
Ever depressed for a whole week	0.6	0.8	1.2	-1.1	-0.6
Cholesterol lowering medication	0.6	0.9	1.0	-0.9	1.0
Deep venous thrombosis (DVT) (self-reported)	0.6	0.8	1.1	1.1	0.6
Bipolar Disorder (2018)	0.5	0.7	1.2	-1.1	-0.5
Age at First Birth	0.5	0.8	1.5	-0.2	-1.2
Rheumatoid Arthritis	0.5	0.7	0.8	0.9	0.8
Schizophrenia (2014)	0.5	1.2	1.4	-1.2	-1.0
Blood Eosinophil Count	0.5	3.6	6.6	-2.6	-0.7
Smoking Status	0.5	1.1	1.3	1.1	0.9
Sensitivity / hurt feelings	0.5	0.8	1.2	1.1	0.6
Pack years adult smoking proportion	0.5	0.7	0.9	-0.9	-0.7
Relative age voice broke	0.5	0.8	0.9	0.9	0.9
Bilateral oophorectomy (both ovaries removed)	0.5	0.6	0.9	1.0	0.4
Medication: Levothyroxine sodium	0.5	0.8	1.3	1.2	0.5
Leg predicted mass (left)	0.5	2.9	3.9	-1.4	-2.0
Time employed in main current job	0.5	0.6	0.9	-1.0	-0.5
Hypertension (Self-reported)	0.5	1.3	2.0	-1.4	-0.8
Illnesses of siblings: Diabetes	0.5	0.6	0.9	1.0	0.5
Leg fat-free mass (right)	0.5	2.5	3.2	-1.3	-1.8
Leg predicted mass (right)	0.5	2.8	3.5	-1.4	-1.9
Tinnitus: Yes, now most or all of the time	0.5	0.5	0.9	-1.0	-0.4
Vascular/heart problems diagnosed by doctor	0.5	1.3	1.6	1.3	1.0
Pack years of smoking	0.5	0.8	0.9	-1.0	-0.8
Schizophrenia (2018)	0.4	0.7	0.9	-0.9	-0.8
Cardiovascular Disease	0.4	1.4	1.9	-1.4	-0.9
Lung FVC	0.4	1.8	3.5	0.4	1.9
Average weekly spirits intake	0.4	0.6	0.6	-0.8	-0.7
High blood pressure	0.4	1.2	1.6	-1.3	-0.9
Chronic bronchitis/emphysema (father)	0.4	0.4	0.9	-0.9	-0.2
Impedance of leg (left)	0.4	1.9	2.6	1.6	1.1
Medication: Ramipril	0.4	0.5	0.9	-1.0	0.0
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.7	1.1	1.0	0.6
Breastfed as a baby	0.4	0.5	0.8	0.4	0.9
Peak expiratory flow (PEF)	0.4	1.0	1.9	-1.4	-0.3
Medication for cholesterol, blood pressure or diabetes	0.4	0.6	1.0	-1.0	-0.4
Arm fat-free mass (right)	0.4	2.1	3.1	1.8	1.0
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.4	0.5	-0.7	-0.6
Health satisfaction	0.4	0.5	0.5	0.7	0.7
Medication: Allopurinol	0.4	0.6	0.9	0.9	0.6
Loneliness, isolation	0.4	0.6	0.8	-0.9	-0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.7	1.3	0.5	1.1
Miserableness	0.4	0.8	1.2	0.6	1.1
Commuting to job workplace: Public transport	0.4	0.5	1.0	0.3	1.0
Medication: Blood pressure	0.4	0.8	1.6	-1.2	-0.2
Fractured/broken bones in last 5 years	0.4	0.5	0.9	-1.0	-0.1
Depression (Nagel 2018)	0.3	0.5	0.9	-0.3	-0.9
Intelligence (Savage-Jansen 2018)	0.3	1.0	1.4	-0.7	-1.2
Reaction Time	0.3	0.5	1.0	0.1	1.0
LDL Cholesterol	0.3	0.5	0.7	0.8	0.6
Blood White Count	0.3	1.9	3.1	-1.8	0.8
Systolic Blood Pressure	0.3	1.4	2.4	-0.6	1.5
Angina	0.3	0.4	0.7	0.3	0.9
Townsend deprivation index at recruitment	0.3	0.4	0.8	-0.9	-0.1
Current tobacco smoking	0.3	0.5	0.6	0.7	0.8
Fed-up feelings	0.3	0.5	1.0	1.0	-0.1
Multivitamins +/- minerals	0.3	0.4	0.7	0.2	-0.8
Diverticular disease/diverticulitis (self-reported)	0.3	0.3	0.3	0.6	-0.5
Forced vital capacity (FVC)	0.3	1.1	1.4	0.9	1.2
Qualifications: None of the above	0.3	0.7	0.8	0.8	0.9
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	0.7	0.3	-0.8
Fluid intelligence score	0.3	0.7	1.3	-0.3	-1.1
Neuroticism score	0.3	0.5	1.1	1.0	0.2
Hair/balding pattern: Pattern 3	0.3	0.4	0.8	0.1	0.9
Mouth/teeth dental problems: Dentures	0.3	0.5	0.9	-0.9	-0.4
Birth weight	0.3	0.7	1.3	0.2	-1.1
Pulse wave peak to peak time	0.3	0.4	0.6	0.8	-0.4
Shortness of breath walking on level ground	0.3	0.3	0.6	0.3	0.8
Emphysema/chronic bronchitis	0.3	0.3	0.4	-0.4	-0.7
Angina (self-reported)	0.3	0.4	0.8	0.1	0.9
Mean time to correctly identify matches	0.3	0.6	1.0	-0.4	1.0
Long-standing illness, disability or infirmity	0.3	0.5	0.9	-0.2	-1.0
Friendships satisfaction	0.3	0.4	0.8	0.1	-0.9
Mother’s age at death	0.3	0.4	0.6	-0.8	-0.4
Irritability	0.3	0.4	0.7	0.8	0.4
Impedance of whole body	0.3	1.3	1.8	-0.9	-1.3
Worry (Nagel 2018)	0.2	0.4	0.7	0.9	0.2
Ovarian Cancer	0.2	0.3	0.5	0.2	-0.7
HbA1C	0.2	0.2	0.4	0.6	0.0
Respiratory disease	0.2	0.4	0.6	0.8	-0.4
Type 2 Diabetes (T2D) (2018)	0.2	0.3	0.6	0.3	0.7
Systolic blood pressure, automated reading	0.2	0.7	1.1	-1.0	0.6
Eye problems/disorders: Diabetes related eye disease	0.2	0.3	0.3	-0.5	-0.5
Vitamin and mineral supplements	0.2	0.2	0.5	-0.1	0.7
Maternal smoking around birth	0.2	0.3	0.4	0.6	0.5
Hayfever, allergic rhinitis or eczema	0.2	0.4	0.7	0.1	-0.9
Supplements: Glucosamine	0.2	0.3	0.4	0.4	0.6
Sitting height	0.2	1.7	2.2	1.5	1.1
Waist circumference	0.2	0.9	1.7	-0.3	-1.3
Past tobacco smoking	0.2	0.4	0.9	0.2	0.9
Allergy	0.2	0.4	0.6	-0.5	0.8
Medication: Simvastatin	0.2	0.3	0.6	0.0	0.8
Alcohol intake versus 10 years previously	0.2	0.2	0.5	0.7	0.0
Asthma	0.2	0.5	0.7	0.8	-0.5
Lung cancer (father)	0.2	0.2	0.3	0.4	0.5
Illnesses of mother	0.2	0.2	0.2	0.5	0.5
Pulse wave Arterial Stiffness index	0.2	0.3	0.3	-0.6	0.4
Glaucoma (self-reported)	0.2	0.2	0.4	0.2	0.6
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	0.7	0.8	0.2
Chronic bronchitis/emphysema (mother)	0.2	0.2	0.3	0.6	0.3
Wheeze or whistling in the chest in last year	0.2	0.4	0.8	-0.1	-0.9
Number of children fathered	0.2	0.2	0.2	-0.5	-0.4
Migraine (self-reported)	0.2	0.2	0.3	0.5	0.4
Comparative height size at age 10	0.2	1.3	1.8	0.9	-1.3
Family relationship satisfaction	0.2	0.3	0.4	-0.6	-0.4
Knee pain experienced in last month	0.2	0.3	0.5	0.7	-0.4
Illnesses of father: Heart disease	0.2	0.2	0.3	-0.6	-0.3
Ever had bowel cancer screening	0.2	0.2	0.4	0.1	-0.7
Diabetes diagnosed by doctor	0.2	0.3	0.4	0.6	0.5
Qualifications: nursing, teaching	0.2	0.3	0.5	-0.3	-0.7
Asthma (self-reported)	0.2	0.5	0.9	1.0	-0.2
Illnesses of father: None of the above (group 1)	0.2	0.3	0.6	0.8	0.1
Supplements: Fish oil (including cod liver oil)	0.2	0.3	0.6	0.8	0.1
Risk taking	0.2	0.2	0.3	0.5	0.5
Pain experienced in last month	0.2	0.3	0.5	-0.3	-0.7
Arm predicted mass (left)	0.2	0.8	1.1	1.1	0.7
Depressed Affect (Nagel 2018)	0.1	0.2	0.3	0.5	-0.5
Neuroticism (Nagel 2018)	0.1	0.2	0.3	0.3	-0.5
Schizophrenia vs Biploar Disorder	0.1	0.1	0.1	-0.3	-0.3
Alzheimer’s Disease (in mother)	0.1	0.1	0.1	0.4	-0.3
Bipolar Disorder (2011)	0.1	0.1	0.2	-0.4	0.0
Mean Putamen Volume	0.1	0.1	0.2	0.2	0.5
HDL Cholesterol	0.1	0.1	0.2	0.0	-0.4
Lupus	0.1	0.1	0.1	-0.3	0.3
Triglycerides	0.1	0.2	0.4	0.6	0.1
Height	0.1	2.7	5.2	2.3	-0.5
Allergy or Eczema	0.1	0.2	0.4	-0.1	-0.6
Hypothyroidism (self reported)	0.1	0.3	0.5	0.7	-0.0
Lung FEV1/FVC ratio	0.1	0.4	0.8	-0.9	0.1
Neuroticism	0.1	0.2	0.4	0.0	-0.6
Tanning	0.1	0.7	1.3	1.1	0.3
Ever had hysterectomy (womb removed)	0.1	0.1	0.3	-0.1	0.5
Supplements: Zinc	0.1	0.1	0.2	-0.1	-0.4
Medication: Metformin	0.1	0.2	0.4	0.6	-0.0
Serious illness, injury or assault to yourself	0.1	0.1	0.2	0.5	0.2
Medication: Atenolol	0.1	0.1	0.2	-0.4	0.4
Nervous feelings	0.1	0.2	0.3	0.6	0.1
Had menopause	0.1	0.2	0.2	-0.4	-0.4
Ever unenthusiastic/disinterested for a whole week	0.1	0.2	0.2	-0.3	-0.5
Mouth/teeth dental problems	0.1	0.2	0.4	0.2	-0.6
Worrier / anxious feelings	0.1	0.2	0.4	0.3	-0.6
Number of live births	0.1	0.1	0.2	-0.2	-0.5
Happiness	0.1	0.2	0.2	-0.5	-0.3
Qualifications: A levels/AS levels or equivalent	0.1	0.2	0.4	-0.6	-0.3
Medication: Ibuprofen (e.g. Nurofen)	0.1	0.1	0.3	-0.1	0.5
Medication: Lansoprazole	0.1	0.2	0.3	-0.6	-0.1
Mouth/teeth dental problems: Bleeding gums	0.1	0.1	0.1	0.3	0.3
Headache pain in last month	0.1	0.2	0.3	-0.5	0.2
Gout (self-reported)	0.1	0.2	0.3	0.6	0.1
Exposure to tobacco smoke outside home	0.1	0.1	0.3	-0.0	-0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.2	0.3	0.6	-0.2
Age at first live birth	0.1	0.1	0.1	0.3	0.3
Medication: Blood pressure	0.1	0.1	0.2	0.5	0.2
Medication: Ibuprofen	0.1	0.2	0.3	-0.5	0.2
Medication: Seretide 50 evohaler	0.1	0.1	0.1	0.3	-0.4
Pulse rate, automated reading	0.1	0.5	1.0	1.0	0.0
Overall health rating	0.1	0.2	0.2	-0.4	-0.4
Had major operations	0.1	0.2	0.3	0.5	-0.2
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.1	0.2	-0.4	-0.1
Whole body fat-free mass	0.1	0.3	0.6	0.8	0.2
Mouth/teeth dental problems: Mouth ulcers	0.1	0.1	0.2	-0.0	0.5
Mineral and other dietary supplements	0.1	0.1	0.3	-0.5	0.2
Number of self-reported non-cancer illnesses	0.1	0.2	0.3	0.6	0.4
Ever taken oral contraceptive pill	0.1	0.2	0.3	0.0	-0.6
Financial situation satisfaction	0.1	0.1	0.2	-0.4	-0.3
Basal metabolic rate	0.1	0.3	0.6	-0.2	-0.8
Arm fat-free mass (left)	0.1	0.6	0.9	1.0	0.6
Age started oral contraceptive pill	0.1	0.1	0.2	0.2	0.4
Unable to work because of sickness or disability	0.1	0.2	0.4	0.1	0.6
Verbal and Numeric Reasoning (VNR)	0.0	0.1	0.1	-0.2	-0.4
Fasting Glucose	0.0	0.0	0.1	0.0	-0.3
Neuroticism (2016)	0.0	0.1	0.1	-0.1	0.3
Chronotype (morning person)	0.0	0.1	0.1	0.2	0.3
Hair Pigment	0.0	1.4	1.7	-1.0	-1.3
Number of treatments/medications taken	0.0	0.0	0.0	-0.2	-0.1
Frequency of depressed mood in last 2 weeks	0.0	0.1	0.1	0.1	-0.3
Other serious medical condition/disability diagnosed by doctor	0.0	0.0	0.0	0.1	-0.0
Frequency of unenthusiasm / disinterest in last 2 weeks	0.0	0.0	0.1	-0.3	0.1
Taking other prescription medications	0.0	0.1	0.1	-0.1	-0.3
Qualifications: CSEs or equivalent	0.0	0.0	0.0	0.1	-0.1
Stomach or abdominal pain in last month	0.0	0.0	0.0	-0.0	-0.1
Frequency of tenseness / restlessness in last 2 weeks	0.0	0.1	0.1	-0.0	0.4
Financial difficulties in last 2 years	0.0	0.0	0.0	-0.1	0.1
Diabetes (self-reported)	0.0	0.0	0.1	-0.3	0.1
Pulse rate	0.0	0.0	0.0	0.1	0.2
Medication: Cholesterol lowering	0.0	0.1	0.1	0.3	-0.2
Medication: Amlodipine	0.0	0.0	0.1	-0.1	-0.3
Neck or shoulder pain in last month	0.0	0.1	0.1	0.1	-0.3
Heart disease (mother)	0.0	0.0	0.0	-0.1	-0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.0	0.0	0.0	0.0	-0.0
Chest pain or discomfort	0.0	0.0	0.0	-0.2	-0.2
Age at last live birth	0.0	0.1	0.1	0.3	-0.1
Illness, injury, bereavement, stress in last 2 years	0.0	0.0	0.1	-0.3	-0.1
Handedness (chirality/laterality): Left-handed	0.0	0.0	0.0	0.0	-0.2
Mood swings	0.0	0.0	0.1	0.0	0.3
Medication for cholesterol	0.0	0.1	0.1	0.2	-0.3
Osteoporosis (self-reported)	0.0	0.0	0.0	0.1	-0.0
Osteoarthritis (self-reported)	0.0	0.0	0.1	0.2	0.1
Whole body water mass	0.0	0.2	0.5	0.7	0.1
Guilty feelings	0.0	0.0	0.0	0.1	0.0
Alcohol drinker status: Never	0.0	0.0	0.0	0.0	0.2
Ever smoked	0.0	0.1	0.2	0.4	0.0
Alcohol drinker status: Previous	0.0	0.0	0.0	-0.2	-0.1

Hub : Genes

HOXA9

Models

Trait associations