Best TWAS P=4.47e-10 · Best GWAS P=2.14e-15 conditioned to 0.972
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | ADAMTS14 | 0.28 | 0.24 | bslmm | 733 | 0.35 | 7.9e-44 | -2.0 | 6.1 | 1.1e-09 | 0.81 | 0.09 | 0.91 | FALSE |
| 2 | GTEx | Artery Tibial | PCBD1 | 0.19 | 0.01 | lasso | 6 | 0.01 | 3.0e-02 | -4.7 | 5.8 | 7.8e-09 | 0.44 | 0.11 | 0.22 | TRUE |
| 3 | GTEx | Esophagus Muscularis | PCBD1 | 0.16 | 0.04 | lasso | 3 | 0.07 | 4.3e-05 | -2.3 | 5.2 | 1.8e-07 | 0.26 | 0.50 | 0.03 | FALSE |
| 4 | ROSMAP | Brain Pre-frontal Cortex | ADAMTS14 | 0.38 | 0.35 | bslmm | 710 | 0.47 | 3.9e-67 | 7.8 | 6.2 | 4.5e-10 | 0.86 | 0.00 | 1.00 | TRUE |