TWAS hub - ADAMTS14

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.2850	0.0360	0.0e+00	0.235	0.289	0.342	0.347	0.339	3.2e-28	1.8e-35	4.5e-43	7.9e-44	1.5e-42
2	ROSMAP	Brain Pre-frontal Cortex	0.3789	0.0389	0.0e+00	0.347	0.397	0.465	0.466	0.454	2.6e-46	1.3e-54	5.9e-67	3.9e-67	7.5e-65
3	TCGA	Breast Invasive Carcinoma	0.0509	0.0168	3.4e-07	0.029	0.019	0.032	NA	0.005	1.2e-06	8.0e-05	3.3e-07	NA	2.2e-02
4	TCGA	Head and Neck Squamous Cell Carcinoma	0.0499	0.0205	1.2e-03	0.017	0.023	0.024	NA	0.028	4.1e-03	1.1e-03	9.0e-04	NA	3.8e-04
5	TCGA	Kidney Renal Papillary Cell Carcinoma	0.1550	0.0590	7.0e-04	-0.004	0.051	0.028	NA	0.010	6.3e-01	6.9e-04	1.0e-02	NA	8.1e-02
6	TCGA	Brain Lower Grade Glioma	0.0778	0.0250	1.5e-06	0.038	0.051	0.032	NA	0.045	3.1e-05	1.8e-06	1.3e-04	NA	6.8e-06
7	TCGA	Lung Squamous Cell Carcinoma	0.0419	0.0209	6.2e-03	0.001	0.011	0.001	NA	0.001	2.6e-01	1.6e-02	2.5e-01	NA	2.1e-01
8	TCGA	Ovarian Serous Cystadenocarcinoma	0.0950	0.0450	9.4e-03	0.051	-0.004	0.010	NA	0.040	2.3e-04	7.2e-01	6.1e-02	NA	1.1e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Impedance of arm (right)	6.1	28.3	69.7	7.8	8.4	6.4	-0.7	-2.8	4.8	2.1	-4.2
Impedance of whole body	5.7	28.9	69.8	7.8	8.4	6.4	-1.0	-2.8	5.1	2.3	-4.3
Impedance of arm (left)	5.6	26.1	64.2	7.5	8.0	6.0	-0.7	-3.1	4.7	2.0	-3.9
Trunk fat percentage	5.4	21.6	47.9	6.8	6.9	4.8	-1.6	-1.9	4.8	2.2	-4.6
Impedance of leg (right)	4.8	23.3	54.7	6.7	7.4	5.8	-1.6	-2.3	4.9	1.8	-4.3
Impedance of leg (left)	4.6	22.2	52.2	6.5	7.2	5.5	-1.9	-1.9	4.9	1.6	-4.4
Body fat percentage	4.5	17.9	38.9	6.1	6.2	4.2	-1.8	-2.0	4.3	1.9	-4.4
Leg fat percentage (right)	3.7	13.3	27.6	5.2	5.3	3.7	-1.6	-1.7	4.2	2.0	-3.4
Fractured/broken bones in last 5 years	3.5	4.6	9.7	-2.4	-2.7	-3.1	0.1	1.2	-2.3	-2.5	1.0
Alzheimer’s Disease (including proxy)	3.2	4.6	8.9	1.6	1.2	1.4	3.0	2.6	1.4	2.7	2.5
Leg fat percentage (left)	3.2	11.5	23.5	4.8	4.8	3.2	-1.8	-1.4	4.0	1.6	-3.3
Trunk fat mass	3.0	12.7	26.6	5.0	5.2	3.4	-1.8	-1.6	3.9	1.4	-4.0
Arm fat percentage (right)	3.0	11.9	26.5	5.1	5.1	3.4	-1.3	-1.5	3.5	1.4	-3.6
Arm fat percentage (left)	2.9	11.4	26.0	5.0	5.1	3.2	-1.2	-1.6	3.5	1.5	-3.4
Medication: Omeprazole	2.6	3.1	7.2	2.7	2.1	2.0	0.2	1.7	2.2	0.6	-0.8
Father’s age at death	2.5	3.3	7.3	-2.4	-2.7	-1.8	0.1	-0.6	-2.7	-1.3	1.0
Back pain experienced in last month	2.5	3.7	8.3	1.9	1.6	2.1	2.9	0.5	1.6	2.6	1.1
Type 2 Diabetes (T2D) (2012)	2.4	2.8	8.4	-1.5	-2.3	-2.9	-0.7	-0.2	-1.8	-1.5	-0.5
Alzheimer’s Disease (in mother)	2.3	2.7	4.3	1.9	1.6	1.5	1.4	2.1	1.9	1.8	-0.1
Neck or shoulder pain in last month	2.3	3.3	9.9	1.4	1.9	1.6	1.8	3.1	1.8	1.2	0.8
Whole body fat mass	2.3	9.6	19.4	4.2	4.4	2.8	-1.8	-1.4	3.4	1.1	-3.8
Alzheimer’s Disease (in father)	2.2	2.4	9.6	0.2	0.0	0.5	1.8	2.1	0.5	1.0	3.1
Hayfever, allergic rhinitis or eczema	2.1	4.5	8.0	2.5	2.8	2.7	1.1	-0.8	2.6	2.3	-0.4
Medication: Lansoprazole	2.1	2.4	4.3	-1.2	-1.5	-2.1	-1.5	-0.6	-1.7	-2.0	-1.4
Ever depressed for a whole week	2.1	2.5	5.2	-1.0	-1.3	-1.7	-1.5	-2.3	-1.6	-0.4	-2.2
HbA1C	2.0	2.2	7.6	1.1	1.4	1.4	0.7	1.2	2.8	1.0	1.4
Headache pain in last month	2.0	3.4	8.3	-2.7	-2.9	-2.2	-0.9	0.2	-2.2	-0.9	-0.4
Shortness of breath walking on level ground	2.0	2.3	7.2	-2.0	-1.7	-1.4	-0.7	-1.2	-2.7	-0.8	-0.1
Commuting to job workplace: Car/motor vehicle	2.0	2.3	4.8	-1.3	-2.2	-1.9	-0.1	1.8	-1.6	-1.3	0.8
Asthma (self-reported)	2.0	3.9	7.6	1.9	1.6	2.0	2.7	2.8	1.3	1.4	1.8
Allergy	1.9	4.3	7.6	-2.4	-2.4	-2.8	-2.0	-1.1	-2.3	-2.2	-0.2
Asthma	1.9	3.7	6.8	1.9	1.5	1.9	2.6	2.5	1.3	1.4	1.7
Length of working week for main job	1.9	2.0	7.6	2.8	2.2	1.3	0.9	-0.2	0.9	0.4	-0.6
Ever had prostate specific antigen (PSA) test	1.9	2.2	5.9	-1.7	-1.8	-1.8	0.7	0.6	-1.3	-0.4	2.4
Hair/balding pattern: Pattern 3	1.8	2.8	5.7	-1.2	-1.4	-2.4	-1.5	-1.3	-2.1	-2.0	-0.6
Medication: Bendroflumethiazide	1.8	2.7	5.5	1.8	2.1	2.3	0.4	-1.0	2.0	1.7	-0.8
Allergy or Eczema	1.7	4.5	9.1	2.3	3.0	2.6	1.1	-0.8	2.6	2.4	-0.5
Diabetes (mother)	1.7	2.2	3.8	2.0	1.7	1.7	1.7	1.6	0.9	1.4	-0.1
Bilateral oophorectomy (both ovaries removed)	1.7	1.9	3.2	-1.8	-1.7	-1.6	-1.4	-1.2	-1.5	-1.0	-0.4
Exposure to tobacco smoke at home	1.7	1.9	4.1	-1.1	-1.4	-1.1	-1.4	-1.4	-2.0	-1.5	-0.8
Leg fat mass (right)	1.7	6.4	12.2	3.3	3.5	2.1	-1.8	-1.4	2.8	0.9	-3.2
Qualifications: NVQ or HND or HNC or equivalent	1.7	2.1	4.1	-0.6	-0.6	-1.2	-2.0	-1.1	-1.3	-1.9	-2.0
Alcohol intake versus 10 years previously	1.6	2.3	4.2	-1.4	-1.7	-1.5	-2.1	-0.7	-1.4	-1.5	-1.5
Number of full brothers	1.6	2.0	4.9	-1.3	-2.2	-2.1	0.3	0.6	-1.7	-0.3	1.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.6	1.9	8.6	0.9	1.4	1.5	0.5	2.9	1.0	0.3	0.3
Medication: Omeprazole (e.g. Zanprol)	1.6	2.0	5.6	2.4	1.5	1.8	0.1	0.9	1.6	0.9	-0.9
Age at First Birth	1.5	2.2	6.7	0.2	0.3	1.1	1.9	2.6	1.4	1.0	1.6
Respiratory disease	1.5	3.4	6.5	2.0	2.1	2.2	2.5	1.6	0.9	1.0	1.8
Alcohol usually taken with meals	1.5	2.4	4.6	-2.0	-1.4	-2.1	0.5	0.3	-1.4	-1.8	1.7
Falls in the last year	1.5	2.1	4.8	-1.6	-1.2	-2.2	-1.5	0.5	-1.4	-1.8	-0.1
Leg fat mass (left)	1.5	5.9	10.6	3.1	3.3	1.9	-1.9	-1.3	2.6	0.8	-3.2
Mean Putamen Volume	1.4	1.6	2.6	-1.6	-1.2	-1.3	-1.5	-1.4	-1.3	-0.5	-0.8
Primary Biliary Cirrhosis	1.4	1.9	5.2	-0.0	-0.0	0.4	2.3	1.2	1.1	1.5	2.3
Medication for hormone replacement therapy	1.4	1.6	2.0	-1.1	-1.4	-1.3	-1.4	-1.3	-1.1	-1.0	-1.4
Medication: Co-codamol	1.4	1.6	3.1	1.3	1.3	1.0	1.8	1.1	0.9	0.5	1.6
Breastfed as a baby	1.4	1.7	3.1	-1.1	-0.9	-1.7	-1.3	-1.2	-1.5	-1.8	-0.6
Medication: Ventolin 100micrograms inhaler	1.4	1.8	4.9	0.4	1.2	0.2	2.0	2.2	0.9	-0.2	1.8
Leg pain on walking	1.4	1.7	6.0	-1.4	-0.9	-0.3	-1.8	-1.0	-0.4	-0.7	-2.5
Tinnitus: Yes, now most or all of the time	1.4	1.7	4.1	1.4	1.3	1.7	0.8	0.6	2.0	1.2	0.6
Alcohol drinker status: Previous	1.4	1.6	4.0	-1.7	-1.2	-0.5	-0.6	-2.0	-1.6	-0.3	0.8
Smoking Status	1.3	3.1	10.4	-1.6	-1.4	-0.9	-1.1	-3.2	-2.4	-1.0	-1.2
Severe depression (siblings)	1.3	1.5	3.5	-1.6	-1.8	-1.2	-0.2	0.3	-1.9	-1.0	-0.1
Arm fat mass (right)	1.3	5.5	11.0	3.3	3.3	2.1	-1.2	-1.2	2.4	0.8	-2.9
Tense / ‘highly strung’	1.3	2.2	5.6	0.3	1.2	1.4	2.1	1.0	1.2	1.3	2.4
Emphysema/chronic bronchitis	1.3	1.5	2.7	-1.7	-1.4	-0.8	-1.2	-0.9	-1.2	-0.7	-1.4
Family relationship satisfaction	1.3	1.6	3.5	1.2	1.8	1.9	0.6	0.6	1.8	0.7	0.3
Ulcerative Colitis	1.2	1.7	4.6	0.9	1.1	1.0	1.3	0.4	1.9	2.1	0.6
Trunk fat-free mass	1.2	6.8	17.7	-4.2	-4.2	-3.3	-0.9	0.5	-1.9	-1.9	0.8
Time employed in main current job	1.2	1.4	5.8	0.6	0.6	-0.0	1.9	1.2	0.3	0.3	2.4
Serious illness, injury or assault of a close relative in last 2 years	1.2	1.4	2.6	-1.3	-1.1	-1.3	-1.6	-1.0	-0.5	-1.2	-1.1
Trunk predicted mass	1.2	6.6	17.2	-4.2	-4.1	-3.2	-0.9	0.5	-1.8	-1.9	0.8
Mouth/teeth dental problems: Loose teeth	1.2	1.4	2.8	1.7	1.6	0.8	1.3	-0.4	0.7	1.6	0.7
Arm fat mass (left)	1.2	4.7	9.1	2.9	3.0	1.8	-1.3	-1.3	2.4	0.8	-2.7
Medication: Atorvastatin	1.2	1.5	5.0	-0.4	0.3	-0.6	-2.1	0.3	0.5	-1.4	-2.2
Bipolar Disorder (2011)	1.1	1.1	3.7	-1.1	-1.5	-0.8	-0.2	-0.7	-1.9	-0.5	-0.1
Ever had hysterectomy (womb removed)	1.1	1.2	3.3	-1.2	-1.8	-1.2	-0.3	-0.8	-1.6	-0.5	0.1
Diabetes (father)	1.1	1.3	2.9	1.4	1.7	1.2	0.8	1.0	1.6	0.2	-0.1
Waist circumference	1.1	3.9	7.1	2.6	2.7	2.1	-0.8	-0.7	2.1	1.2	-2.4
Financial difficulties in last 2 years	1.1	1.4	1.9	-1.4	-1.4	-1.2	-1.0	-0.7	-1.4	-1.0	-1.3
Pain all over the body in last month	1.1	1.2	2.3	-1.0	-0.9	-1.3	-1.4	-1.5	-1.2	-0.1	-0.5
Medication: Ramipril	1.1	1.4	2.9	1.7	1.1	1.2	0.1	0.7	1.7	1.3	-1.0
Arm fat-free mass (right)	1.1	5.9	15.2	-3.8	-3.9	-3.2	-0.8	0.3	-1.7	-1.5	1.1
Arm predicted mass (right)	1.1	5.8	15.3	-3.8	-3.9	-3.2	-1.0	0.3	-1.7	-1.5	0.8
Handedness (chirality/laterality): Left-handed	1.1	1.3	2.5	1.2	1.2	1.4	1.0	0.9	1.0	0.4	1.6
Myopia	1.1	1.6	5.6	-0.8	-2.4	-1.2	0.5	1.4	-0.7	-0.8	1.5
Basal cell carcinoma (self-reported)	1.1	1.3	3.1	1.5	1.8	1.4	-0.4	-0.9	1.2	0.4	-0.7
Heel T-Score	1.0	8.2	15.4	2.8	2.6	3.0	-1.3	-3.1	2.3	3.1	-3.9
Number of treatments/medications taken	1.0	1.8	3.2	1.8	1.8	1.1	0.7	1.8	1.6	0.8	-0.3
High blood pressure (mother)	1.0	1.5	3.9	-1.3	-1.3	-1.7	0.3	-0.7	-2.0	-0.8	0.4
Medication for pain relief, constipation, heartburn	1.0	1.7	4.7	-1.1	-0.9	-1.3	-1.2	-2.2	-1.0	-1.6	-0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.0	1.2	2.4	1.5	1.1	1.5	-0.6	-0.6	0.4	0.7	-1.5
Ever had bowel cancer screening	1.0	1.2	3.6	0.8	0.0	1.0	1.0	1.1	0.5	1.9	1.3
Whole body water mass	1.0	5.6	14.6	-3.7	-3.8	-3.0	-0.8	0.3	-1.9	-1.7	0.6
Mother’s age at death	1.0	1.2	2.9	0.9	0.9	1.1	1.1	0.6	1.4	1.7	0.7
Commuting to job workplace: Cycle	1.0	1.2	3.4	-1.1	-0.9	-1.1	-1.0	-1.9	-0.6	-0.9	-0.5
Sitting height	0.9	6.3	15.1	-3.9	-3.8	-2.5	-1.4	-1.4	-2.8	-1.8	0.3
Hair/balding pattern: Pattern 2	0.9	1.1	2.6	1.2	0.8	1.6	0.7	-0.5	0.9	1.5	-0.8
Mouth/teeth dental problems	0.9	1.4	4.5	-2.1	-1.4	-0.7	-1.4	-0.8	-1.2	-0.4	-0.1
Heart attack	0.9	1.1	3.9	-1.4	-0.8	-0.9	-0.5	-1.0	-2.0	-0.7	-0.3
Hayfever/allergic rhinitis (self-reported)	0.9	1.1	2.5	1.0	1.6	0.7	0.9	1.4	1.2	0.1	1.0
Pulse rate	0.9	1.6	3.2	0.5	0.6	1.8	1.4	-0.9	0.4	1.8	1.6
Birth weight	0.9	1.9	5.8	-1.0	-1.8	-2.4	-0.8	0.7	-1.7	-0.8	-0.5
Wheeze or whistling in the chest in last year	0.9	1.7	5.9	0.1	0.7	0.9	2.4	0.5	0.4	0.8	2.2
Health satisfaction	0.9	1.2	2.8	-0.7	-0.7	-0.7	-1.3	-0.6	-1.4	-1.0	-1.7
Eye problems/disorders: None of the above	0.9	1.1	2.9	0.7	0.0	0.8	1.3	1.7	0.8	1.4	0.6
Medication: Ibuprofen	0.9	1.1	4.0	1.1	0.7	0.4	2.0	0.8	0.4	1.3	0.4
Supplements: Vitamin C	0.9	1.1	3.4	0.3	0.5	-0.3	-1.5	-0.5	0.4	-1.5	-1.8
Whole body fat-free mass	0.9	5.3	13.6	-3.6	-3.7	-3.0	-0.9	0.2	-1.8	-1.6	0.5
Mouth/teeth dental problems: Mouth ulcers	0.9	1.5	4.2	0.7	0.5	1.1	1.9	1.0	0.0	0.9	2.0
Number of self-reported non-cancer illnesses	0.9	1.5	3.3	1.4	1.2	1.3	0.9	1.8	1.1	1.2	-0.2
Medication: Lisinopril	0.9	1.2	2.9	1.3	1.2	1.4	-0.6	-1.7	0.2	0.0	-1.0
Irritable Bowel Disease (IBD)	0.8	1.8	3.1	1.2	0.8	0.9	1.6	1.7	1.8	1.7	0.5
Ulcerative Colitis (UC)	0.8	1.5	3.3	1.1	0.8	0.4	1.7	1.8	1.2	1.2	0.8
Fasting Glucose	0.8	1.0	2.1	-1.3	-1.2	-1.5	-0.5	0.5	-1.2	-0.5	0.6
Rheumatoid Arthritis	0.8	1.1	5.2	-0.3	-0.0	-0.9	0.4	2.3	0.5	-1.2	1.1
Systolic blood pressure, automated reading	0.8	2.2	5.9	1.7	2.1	1.3	-0.1	1.3	2.4	1.1	-0.6
Taking other prescription medications	0.8	1.2	3.9	2.0	1.6	1.2	0.2	0.4	0.9	0.5	-0.6
Heel bone mineral density (BMD) T-score, automated (left)	0.8	1.8	4.1	2.0	1.6	1.9	-0.6	0.3	1.0	0.5	-1.6
Number of live births	0.8	1.2	3.3	-1.4	-1.0	-1.8	-0.7	-0.2	-1.2	-0.3	-1.0
Mouth/teeth dental problems: Dentures	0.8	1.4	4.4	1.5	1.3	0.5	-0.4	0.5	1.4	0.0	-2.1
Lung cancer (father)	0.8	0.9	2.0	1.4	1.2	0.9	0.8	-0.5	0.6	1.3	0.0
Comparative body size at age 10	0.8	2.2	5.3	-1.6	-1.7	-2.3	-1.1	-0.8	-1.5	-1.2	-1.3
Illness, injury, bereavement, stress in last 2 years	0.8	1.0	2.7	0.8	0.8	0.2	-1.0	-1.6	0.3	-0.5	-1.6
Leg fat-free mass (right)	0.8	4.5	11.0	-3.1	-3.3	-2.9	-0.7	0.1	-2.0	-1.6	0.3
Medication: Gliclazide	0.8	0.9	1.8	1.1	1.0	1.2	0.5	0.9	1.3	0.3	0.7
Leg predicted mass (right)	0.8	4.2	10.3	-3.0	-3.2	-2.7	-0.6	0.1	-1.9	-1.5	0.3
Average weekly champagne plus white wine intake	0.8	1.0	2.1	-1.4	-0.8	-0.8	-0.1	-0.7	-1.5	-1.1	1.2
Guilty feelings	0.8	1.2	4.2	-2.0	-1.1	-0.9	-0.4	-0.2	-1.4	-0.8	0.6
Heart attack/myocardial infarction (self-reported)	0.8	1.1	4.0	-1.4	-1.0	-0.9	-0.2	-0.7	-2.0	-0.7	-0.1
Arm predicted mass (left)	0.8	4.0	10.9	-3.1	-3.3	-2.5	-1.0	0.1	-1.5	-1.2	0.2
Depression (Nagel 2018)	0.7	1.0	2.0	-0.2	-0.4	-1.0	-1.1	-1.0	-1.4	-0.9	-1.3
HDL Cholesterol	0.7	1.1	2.5	-0.8	-0.7	-1.1	-1.6	0.3	-0.0	-1.3	-1.4
Chronotype (morning person)	0.7	1.6	4.1	-2.0	-1.7	-1.1	-1.5	0.5	-0.6	-1.0	-1.0
Angina	0.7	0.9	2.5	0.5	0.5	0.8	-1.6	-0.7	0.9	-0.5	-1.2
Supplements: Zinc	0.7	0.7	1.4	1.2	1.2	1.2	0.1	0.8	0.9	0.2	-0.3
Maternal smoking around birth	0.7	1.0	3.0	-1.7	-1.1	-1.0	-0.9	-0.0	-1.4	-0.4	0.2
High blood pressure	0.7	2.0	5.0	1.6	1.7	0.9	-0.1	0.3	1.7	1.4	-2.2
Supplements: Glucosamine	0.7	0.9	6.1	0.2	0.5	-0.4	0.6	2.5	0.4	-0.3	0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.7	1.6	3.1	1.7	1.2	1.6	-0.5	-0.1	0.8	1.4	-1.8
Hip circumference	0.7	3.2	6.2	2.3	2.4	1.8	-1.2	-0.9	1.4	1.0	-2.5
Qualifications: A levels/AS levels or equivalent	0.7	1.5	2.2	1.4	1.5	1.3	1.5	-1.0	1.3	0.8	1.0
Mouth/teeth dental problems: Bleeding gums	0.7	0.9	4.2	0.9	-0.1	-1.0	-0.0	-2.0	-0.4	-1.2	-0.3
Illnesses of father: Heart disease	0.7	1.0	2.2	1.5	1.3	0.7	0.1	1.0	1.3	0.9	-0.6
Illnesses of siblings: Diabetes	0.7	0.8	2.0	-1.2	-1.4	-1.0	-0.4	-0.1	-0.8	1.1	-0.2
Loneliness, isolation	0.7	0.9	4.2	-0.5	-0.4	0.7	1.1	-0.6	0.5	0.9	2.0
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.8	2.1	-0.7	-0.9	-0.8	0.8	0.4	-1.2	0.4	1.5
Osteoporosis (self-reported)	0.7	0.8	1.9	-0.7	-0.3	-0.8	-1.2	-1.4	-0.7	-0.4	-1.2
Irritability	0.7	1.2	1.8	1.0	1.0	0.9	1.4	1.1	0.6	1.4	1.2
Heart disease (siblings)	0.7	0.8	2.9	0.3	1.2	0.2	-0.1	1.7	1.5	-0.2	-0.2
Ovarian Cancer	0.6	0.8	3.2	-0.5	-0.7	-0.2	0.7	1.8	-0.7	-0.1	1.3
Lung FEV1/FVC ratio	0.6	3.1	10.8	-0.2	-0.2	1.0	2.5	0.8	1.1	2.1	3.3
Hand grip strength (left)	0.6	1.7	5.5	0.4	0.5	-0.1	1.5	2.3	1.3	0.8	1.8
Frequency of depressed mood in last 2 weeks	0.6	0.9	2.3	-0.6	-0.6	-1.2	-0.7	-0.3	-1.0	-1.5	-1.0
Other serious medical condition/disability diagnosed by doctor	0.6	0.8	2.3	1.5	0.8	0.8	0.9	-0.2	0.4	1.3	0.3
Eye problems/disorders: Diabetes related eye disease	0.6	0.6	2.4	0.3	0.4	-0.5	-1.0	0.7	0.5	-0.7	-1.5
Townsend deprivation index at recruitment	0.6	0.8	1.9	-1.2	-1.4	0.2	0.6	-0.3	-0.7	0.6	1.3
Serious illness, injury or assault to yourself	0.6	0.7	2.4	-0.6	-1.0	-0.4	-0.7	0.2	-0.8	0.5	-1.6
Multivitamins +/- minerals	0.6	0.8	2.3	-1.1	-0.8	-0.4	0.2	1.5	1.2	0.2	0.5
Chronic bronchitis/emphysema (father)	0.6	0.8	3.0	-0.6	-1.0	-0.6	0.5	1.7	-0.6	0.2	0.9
Noisy workplace	0.6	0.8	4.0	0.3	-0.7	-0.3	0.5	2.0	0.1	0.9	0.7
Medication: Cholesterol lowering	0.6	0.9	2.7	0.3	0.6	0.5	-1.0	1.6	0.9	-0.4	-1.3
Hypothyroidism/myxoedema (self-reported)	0.6	1.2	2.9	1.7	1.1	1.2	0.8	-0.7	1.4	1.1	0.1
Number of children fathered	0.6	0.6	1.4	1.2	0.8	0.8	1.0	0.7	-0.4	0.9	0.2
Angina (self-reported)	0.6	0.8	1.9	0.7	0.7	1.1	-1.4	-0.5	1.0	-0.3	-1.2
Medication: Seretide 50 evohaler	0.6	0.7	1.5	1.1	1.2	1.2	0.6	0.6	0.7	0.1	-0.3
Comparative height size at age 10	0.6	3.2	8.0	-1.8	-1.0	-0.2	-2.8	-2.8	-0.4	-0.2	-2.3
Overall health rating	0.6	1.2	2.6	1.3	1.3	1.6	0.5	0.7	0.9	1.4	-0.7
Knee pain experienced in last month	0.6	0.9	1.7	1.2	0.6	1.3	1.1	1.0	0.8	0.9	0.1
Average weekly red wine intake	0.6	0.9	2.8	-0.5	-0.0	-0.5	-1.0	-1.6	0.1	-1.7	-0.6
Medication: Aspirin	0.6	0.7	2.1	0.9	1.1	0.9	-0.2	0.6	1.4	-0.5	-0.4
Smoking status: Current	0.6	0.9	3.1	-1.2	-0.8	0.3	0.3	-1.8	-1.0	0.6	0.3
Alcohol drinker status: Never	0.6	0.8	1.6	-1.0	-1.0	-1.2	0.2	-0.4	-1.3	0.0	1.0
Arm fat-free mass (left)	0.6	3.2	9.3	-2.8	-3.0	-2.3	-0.7	0.2	-1.3	-1.0	0.4
Risk taking	0.6	0.9	3.2	-0.3	-0.2	0.1	1.5	1.2	0.2	0.1	1.8
Age started oral contraceptive pill	0.6	0.7	2.0	-0.4	-0.2	-1.0	-0.7	-1.4	-1.3	-0.0	-0.8
Diastolic blood pressure, automated reading	0.6	2.0	3.8	1.5	1.3	1.0	1.6	1.9	1.0	1.3	1.4
Vascular/heart problems diagnosed by doctor	0.6	1.6	5.4	-1.3	-1.4	-0.7	0.6	0.2	-1.5	-0.9	2.3
Pain experienced in last month	0.6	1.0	2.4	-1.0	-0.6	-0.8	-1.5	-1.5	-0.5	-1.2	-0.2
Schizophrenia vs Biploar Disorder	0.5	0.7	2.9	0.1	0.7	1.7	0.3	0.4	1.1	0.2	-0.9
Coronary Artery Disease (CAD)	0.5	0.6	3.5	0.4	0.2	0.3	-0.2	0.9	-0.2	-0.0	-1.9
Waist Hip Ratio (WHR)	0.5	2.3	4.9	2.0	2.2	1.9	0.6	0.2	2.0	0.8	-0.8
Type 2 Diabetes (T2D) (2018)	0.5	0.9	2.8	-0.4	-0.2	-0.8	0.1	1.7	1.5	-1.1	0.7
Lung FVC	0.5	2.7	7.2	2.7	2.1	1.7	0.3	1.0	2.1	1.0	-1.0
Leg fat-free mass (left)	0.5	2.9	7.1	-2.4	-2.7	-2.3	-0.7	-0.2	-1.5	-1.2	0.0
Current tobacco smoking	0.5	0.8	2.7	-1.3	-0.8	0.2	0.2	-1.6	-1.0	0.6	0.2
Average weekly fortified wine intake	0.5	0.6	1.1	0.2	0.5	1.0	0.8	-1.0	0.2	1.0	0.9
Relative age voice broke	0.5	0.8	3.5	1.9	1.2	0.4	0.5	-0.6	0.2	0.5	0.1
Medication: Atenolol	0.5	0.6	2.6	-0.4	0.1	0.3	-1.0	-1.6	0.1	-0.3	-1.1
Leg predicted mass (left)	0.5	2.9	7.0	-2.4	-2.6	-2.3	-0.7	-0.3	-1.5	-1.3	0.0
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	1.8	-0.5	-0.9	-0.8	-0.3	-0.9	-0.6	0.1	-1.3
Happiness	0.5	0.7	1.7	0.2	-0.3	0.4	0.9	-0.8	-1.3	0.7	1.2
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.6	2.0	0.7	0.0	0.2	1.4	0.5	0.1	1.4	0.0
Depression (self-reported)	0.5	0.6	1.0	-0.9	-0.9	-0.7	0.4	-0.9	-1.0	0.8	0.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.7	4.7	2.2	1.5	1.6	0.9	-0.2	1.5	0.7	0.1
Birth weight of first child	0.5	0.8	1.9	1.0	1.4	0.3	-0.5	-0.7	1.2	-0.2	-1.1
Ever highly irritable/argumentative for 2 days	0.5	0.6	1.9	-0.1	-1.1	-0.7	0.7	0.6	-1.4	-0.1	0.2
Medication: Paracetamol	0.5	0.8	2.4	-1.2	-1.2	-0.8	-0.1	0.6	-1.5	-0.0	0.3
Medication for cholesterol, blood pressure or diabetes	0.5	0.8	2.9	-0.4	-0.9	-0.1	0.8	-1.0	-1.0	0.1	1.7
Chronic bronchitis/emphysema (mother)	0.5	0.5	1.8	0.6	0.7	1.3	-0.1	0.8	0.9	0.3	0.2
Forced vital capacity (FVC), Best measure	0.5	1.7	4.7	2.2	1.7	1.6	0.1	-0.4	1.4	0.3	-1.0
Number of full sisters	0.5	0.6	1.3	-0.1	-0.8	-1.0	1.2	0.5	-1.1	0.1	0.9
Had major operations	0.5	0.6	2.3	0.2	0.4	0.1	-0.4	1.5	1.0	-0.1	-1.0
Hypertension (Self-reported)	0.5	1.4	3.8	1.4	1.4	0.5	-0.1	0.2	1.4	1.2	-1.9
Diabetes diagnosed by doctor	0.5	0.8	4.2	0.5	0.2	-0.4	0.5	0.7	2.0	-0.1	0.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.0	1.7	1.3	1.1	1.2	0.4	-0.3	0.8	1.1	-1.1
Wears glasses or contact lenses	0.5	0.6	1.4	0.1	-0.4	-0.9	-1.1	1.2	0.7	-0.4	-0.8
Hearing aid user	0.5	0.6	1.3	-1.1	-0.8	-0.5	-1.0	-0.6	-1.0	-0.4	-0.4
Illnesses of father: High blood pressure	0.5	0.6	1.1	0.3	1.1	0.3	1.0	0.8	0.9	-0.6	0.9
Number of operations (self-reported)	0.5	0.8	2.0	0.8	0.5	0.9	1.1	1.4	0.6	0.4	1.0
Average weekly beer plus cider intake	0.5	0.7	4.8	0.1	-0.5	0.1	0.3	2.2	0.5	0.4	0.3
Bipolar Disorder or Schizophrenia	0.4	0.9	3.9	-0.1	-0.2	-0.2	-1.3	-2.0	-0.3	-0.2	-1.2
Depressed Affect (Nagel 2018)	0.4	0.8	1.7	0.7	1.0	0.7	0.7	1.0	1.3	0.7	0.8
Schizophrenia (2018)	0.4	0.7	2.3	-0.6	-0.5	-0.3	-1.2	-1.5	-0.5	-0.2	-1.1
Crohns Disease (2017)	0.4	0.8	2.0	0.7	0.2	0.7	0.6	1.1	1.3	1.4	-0.2
Systolic Blood Pressure	0.4	1.9	5.0	0.6	2.2	1.8	-0.8	-0.2	1.6	0.6	-1.7
Medication: Metformin	0.4	0.6	2.3	-0.6	-0.6	-1.5	-0.4	-0.3	0.2	-1.0	0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.6	2.1	0.6	0.8	0.3	0.1	-0.8	-0.4	0.7	-1.4
Age when periods started (menarche)	0.4	1.0	3.2	-0.4	-0.7	-1.8	0.0	1.0	-1.0	-1.3	-0.3
Had menopause	0.4	0.5	1.1	-0.9	-1.1	-0.2	-0.2	-0.6	-1.0	0.6	0.6
Had other major operations	0.4	0.5	2.7	0.1	0.0	0.3	0.1	1.7	0.4	-0.3	1.1
Qualifications: None of the above	0.4	0.8	2.4	-0.3	0.1	1.0	1.1	0.2	0.4	1.6	1.1
Diabetes (self-reported)	0.4	0.6	1.3	-0.8	-0.7	-1.2	-0.3	-0.4	0.9	-1.0	0.5
Worrier / anxious feelings	0.4	0.8	2.5	-0.1	-0.2	-0.8	1.3	1.1	0.1	-0.5	1.6
Loud music exposure frequency	0.4	0.4	0.9	0.2	-0.1	-0.9	0.4	0.9	0.8	-0.7	0.7
Gout (self-reported)	0.4	0.6	1.6	0.7	0.9	0.1	-0.4	-0.9	0.9	0.0	-1.3
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.5	1.4	0.4	0.1	-0.9	0.7	1.2	-0.3	-0.6	0.8
Age at first live birth	0.4	0.8	1.3	0.8	0.9	1.0	1.2	0.6	0.5	0.8	1.1
Medication: Blood pressure	0.4	0.8	3.5	0.3	0.9	-0.0	-0.9	0.1	1.0	0.1	-1.9
Alcohol intake frequency.	0.4	1.0	4.6	-0.8	-0.7	-0.5	-1.1	-2.1	-0.8	-0.2	-0.8
Suffer from ‘nerves’	0.4	0.6	1.4	-1.1	-1.0	-1.2	-0.4	-1.0	-0.7	-0.0	-0.3
Medication: Aspirin	0.4	0.5	1.5	0.8	1.0	0.9	-0.1	0.2	1.2	0.1	-0.3
Mood swings	0.4	0.7	2.7	0.8	1.0	0.7	0.8	1.6	0.7	-0.1	-0.1
Eye problems/disorders: Cataract	0.4	0.5	2.3	0.1	0.5	-0.5	-0.4	-1.5	-0.5	-0.6	0.4
Illnesses of father: None of the above (group 1)	0.4	0.5	2.7	-0.8	-0.4	-0.4	-0.5	-1.6	-0.2	-0.3	-0.5
Ever taken oral contraceptive pill	0.4	0.4	2.1	0.0	-0.1	-0.2	1.5	0.1	0.0	0.3	1.1
Medication: Paracetamol	0.4	0.6	1.8	-1.0	-0.9	-0.9	-0.3	0.2	-1.3	-0.0	0.0
Basal metabolic rate	0.4	2.4	6.1	-2.4	-2.5	-2.0	-0.9	-0.1	-1.1	-1.2	-0.1
Verbal and Numeric Reasoning (VNR)	0.3	0.6	2.0	-0.2	-0.4	0.7	0.9	0.1	1.0	1.4	0.8
Triglycerides	0.3	0.5	1.9	-0.5	-0.9	-0.8	0.3	-0.1	-1.4	0.2	0.7
Cardiovascular Disease	0.3	1.1	4.0	0.6	1.3	0.7	-0.6	0.6	1.2	0.5	-2.0
Hypothyroidism (self reported)	0.3	0.8	1.8	1.3	0.5	-0.0	-0.5	-0.6	1.3	0.1	-1.3
Hearing difficulty/problems: Yes	0.3	0.5	2.0	-0.8	-0.7	-0.3	0.1	-0.1	-1.4	-0.1	0.6
Ever used hormone-replacement therapy (HRT)	0.3	0.4	1.0	-0.7	-1.0	-0.4	-0.5	-1.0	-0.5	0.3	-0.3
Vitamin and mineral supplements	0.3	0.4	1.5	0.4	0.3	0.1	0.2	-1.1	-1.2	0.0	0.4
Pack years adult smoking proportion	0.3	0.5	1.1	-1.0	-0.3	0.1	1.1	1.0	-0.2	-0.1	0.8
Hand grip strength (right)	0.3	0.8	1.7	1.1	0.8	0.3	0.8	1.3	1.3	0.1	0.1
Stomach or abdominal pain in last month	0.3	0.4	0.7	-0.7	-0.3	-0.4	-0.8	0.5	-0.8	-0.3	-0.7
Number of incorrect matches in round	0.3	0.6	3.0	-0.4	-0.4	0.1	0.7	0.8	-0.4	-0.0	1.7
Fluid intelligence score	0.3	0.7	1.1	0.5	1.0	0.9	1.1	-0.2	1.0	1.0	0.2
Illnesses of siblings	0.3	0.5	1.3	0.7	0.1	0.5	1.1	-0.6	-0.3	0.3	1.1
Weight	0.3	1.5	3.3	1.3	1.3	0.9	-1.1	-1.0	1.4	0.6	-1.8
Peak expiratory flow (PEF)	0.3	0.7	2.1	1.3	0.8	0.1	1.5	-0.2	-0.4	-0.3	1.1
Glaucoma (self-reported)	0.3	0.4	2.2	0.1	0.2	0.7	0.3	-0.3	-1.5	-0.1	0.6
Medication: Amlodipine	0.3	0.4	1.4	-0.0	-0.1	-1.2	-0.2	-0.4	-0.5	-1.2	-0.1
Exposure to tobacco smoke outside home	0.3	0.4	0.9	-0.4	-0.9	-0.9	-0.3	0.5	0.3	-0.5	-0.6
Worry too long after embarrassment	0.3	0.5	1.8	-0.2	0.3	-0.5	0.2	1.4	0.3	-1.0	0.4
Pulse wave peak to peak time	0.3	0.4	0.9	0.9	0.6	0.6	0.3	-0.7	0.7	-0.1	0.5
Pulse rate, automated reading	0.3	0.8	2.0	0.0	-0.3	0.7	1.4	-0.6	0.0	1.4	1.3
Chest pain or discomfort	0.3	0.4	1.0	-0.2	-0.1	-1.0	-0.0	0.5	-1.0	-1.0	0.3
Smoking status: Previous	0.3	0.5	1.2	-0.0	-0.1	-0.5	-0.8	-0.5	-0.6	-1.0	-1.1
Friendships satisfaction	0.3	0.4	1.3	0.3	0.4	0.5	1.0	-0.4	0.2	0.5	1.1
Mineral and other dietary supplements	0.3	0.3	1.5	0.5	-0.3	-0.4	-0.0	-1.2	-0.9	0.1	0.2
Financial situation satisfaction	0.3	0.4	2.5	-0.0	-0.1	-0.3	-0.1	-1.6	-0.1	0.7	-0.5
Commuting to job workplace: Public transport	0.3	0.4	2.3	-0.1	0.5	0.4	0.3	-1.5	0.2	-0.3	0.4
Supplements: Fish oil (including cod liver oil)	0.3	0.3	1.0	-0.9	-0.2	0.3	0.1	1.0	0.8	0.3	0.3
High cholesterol (Self-reported)	0.3	0.6	2.2	0.8	0.7	0.7	-0.3	1.5	0.5	-0.1	-0.8
Ever smoked	0.3	0.5	2.9	-0.4	-0.3	0.3	-0.5	-1.7	-0.4	-0.7	-0.2
Pack years of smoking	0.3	0.4	1.3	-1.1	-0.5	-0.1	0.4	1.0	-0.4	-0.5	0.3
Bipolar Disorder (2018)	0.2	0.4	1.6	0.7	0.3	-0.0	-0.6	-1.2	0.1	-0.1	-0.6
Intelligence (Savage-Jansen 2018)	0.2	0.5	1.6	-0.5	-0.5	0.7	0.5	0.8	1.3	0.1	0.6
Neuroticism (Nagel 2018)	0.2	0.4	1.1	0.0	0.6	0.1	0.8	0.9	0.5	0.4	1.0
Worry (Nagel 2018)	0.2	0.4	2.1	-0.3	0.2	-0.2	1.0	0.0	0.2	0.4	1.4
Major Depression (MDD)	0.2	0.3	1.6	-0.0	0.0	0.2	0.3	1.3	-0.1	-0.5	-0.3
Breast Cancer	0.2	0.4	1.1	1.1	0.6	-0.2	0.6	0.5	-0.4	-0.4	0.7
Prostate Cancer	0.2	0.3	0.6	0.1	-0.8	-0.6	0.2	0.8	-0.7	-0.6	0.5
Body Mass Index (BMI) (2010)	0.2	0.2	0.6	0.7	-0.1	-0.1	-0.5	-0.2	0.3	-0.5	-0.7
Crohns Disease (2012)	0.2	0.2	0.9	-1.0	-0.6	-0.4	0.1	0.5	-0.0	-0.4	0.3
LDL Cholesterol	0.2	0.4	0.9	0.3	-0.4	0.0	-0.8	-0.8	-0.5	0.2	-1.0
Blood Red Count	0.2	1.9	4.4	2.1	1.3	1.8	0.2	0.2	2.0	1.2	-0.6
Height	0.2	4.3	11.6	2.1	2.3	2.3	-1.2	0.0	3.4	0.8	-2.4
Relative age of first facial hair	0.2	0.5	1.6	1.3	1.0	0.1	0.9	-0.3	0.1	0.4	0.6
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.5	-0.2	-0.7	-0.5	0.2	0.3	-0.3	0.5	0.4
Diverticular disease/diverticulitis (self-reported)	0.2	0.3	0.8	0.5	-0.6	-0.0	-0.5	0.7	0.1	0.1	-0.9
Medication: Levothyroxine sodium	0.2	0.4	1.2	0.8	0.3	0.5	0.5	-0.2	1.1	0.7	-0.5
Body mass index (BMI)	0.2	0.7	1.5	1.2	1.0	0.5	-0.4	-0.1	1.1	0.6	-1.1
Past tobacco smoking	0.2	0.3	0.9	0.1	0.2	0.1	0.6	0.9	0.5	0.9	0.8
Nervous feelings	0.2	0.3	1.1	0.1	0.9	0.2	1.1	0.2	0.6	-0.1	0.6
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	0.7	0.4	0.7	0.3	0.2	-0.5	-0.1	0.9	-0.6
Hearing difficulty/problems with background noise	0.2	0.2	0.8	0.3	0.2	0.2	0.7	-0.3	-0.1	0.6	0.9
Forced expiratory volume in 1-second (FEV1)	0.2	0.7	2.3	1.5	0.9	0.7	0.7	0.4	1.0	0.2	0.3
Prospective memory result	0.2	0.3	2.1	0.3	-0.0	0.1	-0.2	-1.5	-0.2	0.3	-0.2
Pulse wave Arterial Stiffness index	0.2	0.2	0.5	-0.7	-0.3	-0.3	-0.2	0.5	-0.4	0.3	-0.5
Standing height	0.2	1.6	3.9	0.4	0.8	0.8	-1.8	-1.6	0.9	-0.5	-2.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.2	0.9	0.5	0.3	0.5	-0.2	-1.0	-0.0	0.5	-0.4
Hair/balding pattern: Pattern 4	0.2	0.6	2.4	0.5	0.3	0.7	-0.7	0.3	1.6	0.3	-0.8
Blood clot in the leg (DVT)	0.2	0.2	0.6	0.0	0.5	0.6	0.2	0.2	0.6	-0.1	-0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.3	0.6	0.2	-0.2	-0.1	0.5	-0.8	-0.8	0.7	0.2
Medication: Allopurinol	0.2	0.2	0.7	-0.3	-0.3	-0.7	-0.5	-0.8	0.2	-0.2	-0.3
Heart disease (mother)	0.2	0.3	0.5	0.2	0.7	0.6	0.5	0.7	0.6	-0.0	0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.2	0.4	-0.5	-0.6	-0.5	-0.1	0.2	-0.6	-0.2	0.5
Long-standing illness, disability or infirmity	0.2	0.3	0.8	0.8	0.3	0.7	-0.0	0.4	0.2	0.9	-0.4
Qualifications: nursing, teaching	0.2	0.3	1.0	1.0	0.6	0.4	1.0	0.2	-0.3	0.3	-0.1
Commuting to job workplace: Walk	0.2	0.2	0.6	-0.2	0.5	-0.4	-0.3	-0.1	0.5	-0.8	-0.4
Breast cancer (self-reported)	0.2	0.2	0.6	0.3	0.1	-0.5	-0.1	-0.8	-0.4	-0.8	-0.2
Osteoarthritis (self-reported)	0.2	0.2	0.9	0.1	-0.1	-0.3	0.9	1.0	0.2	0.0	0.2
Eye problems/disorders: Glaucoma	0.2	0.3	1.5	-0.5	0.1	0.2	-0.2	-0.1	-1.2	-0.4	-0.0
Supplements: Calcium	0.2	0.2	0.9	-0.1	-0.5	-0.3	-0.5	0.4	-0.1	-0.0	-1.0
Reaction Time	0.1	0.3	0.8	-0.2	0.2	-0.7	-0.4	0.2	0.7	-0.9	-0.1
Lupus	0.1	0.1	0.4	-0.1	-0.1	-0.0	-0.7	-0.0	-0.1	-0.6	-0.1
Neuroticism (2016)	0.1	0.1	0.2	0.4	0.0	0.3	0.3	-0.3	-0.2	0.3	0.4
Schizophrenia (2014)	0.1	0.2	1.1	-0.1	-0.1	0.5	-0.2	-1.1	0.1	0.2	-0.1
Blood Eosinophil Count	0.1	0.4	2.0	-0.2	-0.2	-0.1	-0.1	-1.4	-0.9	-0.5	0.2
Blood Platelet Count	0.1	0.8	2.2	1.3	1.2	0.5	0.6	-1.5	-0.2	0.6	0.1
Blood White Count	0.1	1.0	2.0	1.1	1.4	1.4	1.1	0.1	0.6	1.1	0.7
BMI	0.1	0.4	1.1	0.7	0.5	0.4	-0.8	-0.6	0.3	-0.0	-1.1
Neuroticism	0.1	0.1	0.8	-0.3	0.1	-0.2	0.2	0.2	0.1	-0.2	0.9
Average weekly spirits intake	0.1	0.1	0.3	0.5	-0.2	0.5	0.4	-0.4	-0.5	0.2	0.0
Fed-up feelings	0.1	0.2	0.8	-0.3	0.0	-0.4	-0.2	0.9	-0.1	-0.5	-0.5
Qualifications: CSEs or equivalent	0.1	0.2	0.7	-0.5	-0.2	-0.2	-0.1	0.8	0.2	-0.6	-0.5
Forced vital capacity (FVC)	0.1	0.4	1.5	1.2	0.6	0.5	-0.2	-0.3	0.3	-0.1	-0.8
Medication: Simvastatin	0.1	0.1	0.2	-0.2	-0.3	-0.3	-0.5	0.3	-0.0	-0.2	-0.3
Neuroticism score	0.1	0.2	0.7	-0.4	0.2	-0.1	0.6	0.5	0.4	0.2	0.9
Illnesses of mother	0.1	0.1	0.3	0.4	0.2	0.0	-0.3	-0.5	0.3	-0.6	0.1
Pulse wave reflection index	0.1	0.2	0.5	-0.5	-0.2	-0.7	-0.4	0.4	-0.2	-0.0	-0.4
Qualifications: O levels/GCSEs or equivalent	0.1	0.1	0.5	-0.1	-0.3	0.0	-0.5	-0.4	0.1	-0.2	-0.7
High blood pressure (siblings)	0.1	0.2	0.6	-0.7	-0.2	0.3	0.1	0.4	0.0	0.4	0.6
Qualifications: College or University degree	0.1	0.2	0.4	0.4	0.4	-0.1	-0.3	-0.7	0.4	-0.6	-0.3
Migraine (self-reported)	0.1	0.1	0.6	-0.2	-0.1	-0.0	0.1	0.3	-0.3	0.8	-0.5
Mean time to correctly identify matches	0.1	0.2	0.5	0.1	0.2	-0.0	-0.7	0.5	0.7	-0.2	0.1
Age at last live birth	0.1	0.1	0.3	0.1	0.3	0.6	0.5	0.5	-0.2	0.1	-0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.2	1.2	0.3	0.6	0.3	-0.0	-1.1	0.1	-0.0	-0.4
Medication for cholesterol	0.1	0.2	0.8	-0.1	0.8	0.4	0.0	-0.9	-0.3	0.0	0.0
Miserableness	0.1	0.1	0.3	-0.5	0.0	-0.3	0.2	0.5	-0.3	0.5	-0.4
Medication: Blood pressure	0.1	0.3	0.8	0.9	0.2	0.7	0.3	-0.1	0.3	0.6	-0.4
Pain type(s) experienced in last month: Hip pain	0.1	0.1	0.5	0.2	-0.2	-0.0	-0.6	0.7	0.4	-0.2	-0.4
Unable to work because of sickness or disability	0.1	0.1	0.3	0.0	0.5	0.2	-0.1	-0.2	0.5	0.2	0.1
Cholesterol lowering medication	0.1	0.1	0.2	-0.1	-0.5	-0.5	-0.4	0.1	0.5	-0.4	-0.1
Deep venous thrombosis (DVT) (self-reported)	0.1	0.2	0.5	0.1	0.6	0.6	0.4	0.2	0.7	0.1	-0.3
Hair Pigment	0.0	0.4	1.5	0.3	0.6	0.2	1.2	-0.2	0.4	0.3	0.9
Tanning	0.0	0.2	0.5	-0.1	-0.4	0.3	0.2	0.7	-0.6	-0.0	0.6
Sensitivity / hurt feelings	0.0	0.1	0.4	0.0	0.4	0.1	0.0	0.1	0.6	-0.1	0.2
Frequency of tiredness / lethargy in last 2 weeks	0.0	0.1	0.2	-0.3	-0.3	-0.1	0.1	0.4	0.2	0.3	0.3

Hub : Genes

ADAMTS14

Models

Trait associations