[Hub]/) : Traits : Whole body fat mass : ← →

chr11:26,818,083-29,054,545

Best TWAS P=3.31e-25 · Best GWAS P=1.04e-33 conditioned to 0.000103

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous LIN7C 0.08 0.06 lasso 1 0.04 4.1e-04 10.32 10.3 5.4e-25 0.63 0.74 0.14 FALSE
2 GTEx Brain Putamen basal ganglia BDNF-AS 0.22 0.17 lasso 4 0.13 5.5e-04 -6.99 8.3 8.5e-17 0.33 0.23 0.05 FALSE
3 GTEx Cells Transformed fibroblasts LIN7C 0.26 0.22 lasso 6 0.25 1.4e-18 10.32 8.5 2.2e-17 0.62 1.00 0.00 FALSE
4 GTEx Esophagus Muscularis LIN7C 0.14 0.08 enet 11 0.07 5.4e-05 3.16 7.2 4.8e-13 0.60 0.70 0.15 FALSE
5 GTEx Liver METTL15 0.18 0.05 lasso 3 0.09 1.9e-03 0.49 -8.2 2.1e-16 -0.68 0.02 0.83 FALSE
6 GTEx Nerve Tibial LIN7C 0.18 0.08 enet 27 0.12 4.2e-09 10.32 6.1 1.0e-09 0.56 0.61 0.36 FALSE
7 GTEx Thyroid LIN7C 0.08 0.04 lasso 4 0.04 6.0e-04 10.32 9.9 4.4e-23 0.69 0.53 0.35 FALSE
8 NTR Blood LIN7C 0.01 0.00 lasso 3 0.01 2.2e-03 10.61 -10.4 3.3e-25 -0.72 0.10 0.80 TRUE
9 ROSMAP Brain Pre-frontal Cortex METTL15 0.04 0.03 blup 364 0.03 4.6e-05 -3.11 -5.4 7.1e-08 -0.19 0.72 0.01 TRUE
10 The Cancer Genome Atlas Bladder Urothelial Carcinoma LIN7C 0.04 0.01 lasso 3 0.02 1.0e-02 -1.69 6.1 1.3e-09 0.46 0.02 0.83 FALSE
11 The Cancer Genome Atlas Colon Adenocarcinoma LIN7C 0.10 0.03 blup 32 0.08 2.8e-05 10.66 8.2 3.0e-16 0.57 0.01 0.96 FALSE
12 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma LIN7C 0.05 0.02 lasso 3 0.03 2.9e-04 10.71 9.5 1.9e-21 0.63 0.00 0.99 FALSE
13 The Cancer Genome Atlas Brain Lower Grade Glioma LIN7C 0.09 0.12 lasso 2 0.12 2.6e-13 3.29 5.7 1.5e-08 0.52 0.92 0.08 FALSE
14 The Cancer Genome Atlas Lung Adenocarcinoma LIN7C 0.02 0.02 enet 3 0.02 5.6e-03 2.03 5.2 1.8e-07 0.52 0.01 0.73 TRUE