[Hub]/) : Traits : Whole body fat mass : ← →

chr11:26,818,083-29,054,545

Best TWAS P=3.31e-25 · Best GWAS P=1.04e-33 conditioned to 0.000103

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
8	NTR	Blood	LIN7C	0.01	0.00	lasso	3	0.01	2.2e-03	10.61	-10.4	3.3e-25	-0.72	0.10	0.80	TRUE
9	ROSMAP	Brain Pre-frontal Cortex	METTL15	0.04	0.03	blup	364	0.03	4.6e-05	-3.11	-5.4	7.1e-08	-0.19	0.72	0.01	TRUE
14	The Cancer Genome Atlas	Lung Adenocarcinoma	LIN7C	0.02	0.02	enet	3	0.02	5.6e-03	2.03	5.2	1.8e-07	0.52	0.01	0.73	TRUE
1	GTEx	Adipose Subcutaneous	LIN7C	0.08	0.06	lasso	1	0.04	4.1e-04	10.32	10.3	5.4e-25	0.63	0.74	0.14	FALSE
7	GTEx	Thyroid	LIN7C	0.08	0.04	lasso	4	0.04	6.0e-04	10.32	9.9	4.4e-23	0.69	0.53	0.35	FALSE
12	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	LIN7C	0.05	0.02	lasso	3	0.03	2.9e-04	10.71	9.5	1.9e-21	0.63	0.00	0.99	FALSE
3	GTEx	Cells Transformed fibroblasts	LIN7C	0.26	0.22	lasso	6	0.25	1.4e-18	10.32	8.5	2.2e-17	0.62	1.00	0.00	FALSE
2	GTEx	Brain Putamen basal ganglia	BDNF-AS	0.22	0.17	lasso	4	0.13	5.5e-04	-6.99	8.3	8.5e-17	0.33	0.23	0.05	FALSE
5	GTEx	Liver	METTL15	0.18	0.05	lasso	3	0.09	1.9e-03	0.49	-8.2	2.1e-16	-0.68	0.02	0.83	FALSE
11	The Cancer Genome Atlas	Colon Adenocarcinoma	LIN7C	0.10	0.03	blup	32	0.08	2.8e-05	10.66	8.2	3.0e-16	0.57	0.01	0.96	FALSE
4	GTEx	Esophagus Muscularis	LIN7C	0.14	0.08	enet	11	0.07	5.4e-05	3.16	7.2	4.8e-13	0.60	0.70	0.15	FALSE
6	GTEx	Nerve Tibial	LIN7C	0.18	0.08	enet	27	0.12	4.2e-09	10.32	6.1	1.0e-09	0.56	0.61	0.36	FALSE
10	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	LIN7C	0.04	0.01	lasso	3	0.02	1.0e-02	-1.69	6.1	1.3e-09	0.46	0.02	0.83	FALSE
13	The Cancer Genome Atlas	Brain Lower Grade Glioma	LIN7C	0.09	0.12	lasso	2	0.12	2.6e-13	3.29	5.7	1.5e-08	0.52	0.92	0.08	FALSE