Best TWAS P=4.23e-10 · Best GWAS P=4.05e-13 conditioned to 3.93e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Frontal Cortex BA9 | TEX29 | 0.45 | 0.10 | lasso | 8 | 0.24 | 4.2e-07 | -4.7 | -6.2 | 4.2e-10 | -0.40 | 0.08 | 0.36 | TRUE |
| 2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ARHGEF7 | 0.09 | 0.07 | blup | 142 | 0.08 | 3.1e-09 | -4.8 | 6.0 | 1.5e-09 | 0.39 | 1.00 | 0.00 | TRUE |