TWAS
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Usage
Models
Genes
Traits
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Traits
:
Whole body fat mass
:
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chr15:51,040,798-52,612,484
Best TWAS P=2.06e-07 · Best GWAS P=3.45e-08 conditioned to 0.0444
51M
51.2M
51.4M
51.6M
51.8M
52M
52.2M
52.4M
52.6M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Cells Transformed fibroblasts
DMXL2
0.06
0.06
lasso
3
0.05
5.9e-05
5.3
-5.2
2.1e-07
-0.87
0.03
0.96
TRUE