Best TWAS P=1.18e-07 · Best GWAS P=1.25e-05 conditioned to 0.656
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | PKD1P6 | 0.15 | 0.07 | lasso | 5 | 0.05 | 6.8e-05 | 4.2 | 5.1 | 2.8e-07 | 0.47 | 0.01 | 0.83 | FALSE |
| 2 | GTEx | Heart Left Ventricle | RRN3 | 0.24 | 0.12 | lasso | 7 | 0.17 | 2.2e-09 | 4.3 | -5.3 | 1.2e-07 | -0.87 | 0.01 | 0.91 | TRUE |
| 3 | NTR | Blood | PDXDC1 | 0.12 | 0.12 | enet | 26 | 0.15 | 1.3e-46 | -3.6 | 5.2 | 1.6e-07 | 0.74 | 0.06 | 0.49 | FALSE |