TWAS
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Traits
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Whole body fat mass
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chr16:14,379,931-15,946,778
Best TWAS P=1.18e-07 · Best GWAS P=1.25e-05 conditioned to 0.656
14.4M
14.6M
14.8M
15M
15.2M
15.4M
15.6M
15.8M
16M
0
1
2
3
4
5
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Heart Left Ventricle
RRN3
0.24
0.12
lasso
7
0.17
2.2e-09
4.3
-5.3
1.2e-07
-0.87
0.01
0.91
TRUE
3
NTR
Blood
PDXDC1
0.12
0.12
enet
26
0.15
1.3e-46
-3.6
5.2
1.6e-07
0.74
0.06
0.49
FALSE
1
GTEx
Adipose Subcutaneous
PKD1P6
0.15
0.07
lasso
5
0.05
6.8e-05
4.2
5.1
2.8e-07
0.47
0.01
0.83
FALSE