Best TWAS P=9.34e-35 · Best GWAS P=9.21e-140 conditioned to 3.08e-70
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | FTO | 0.11 | 0.00 | bslmm | 739 | 0.02 | 1.6e-03 | -1.5 | 11.8 | 2.9e-32 | 0.38 | 0.09 | 0.55 | TRUE |
| 2 | GTEx | Muscle Skeletal | RBL2 | 0.11 | 0.00 | lasso | 5 | 0.00 | 2.9e-01 | 2.0 | -5.4 | 8.1e-08 | -0.10 | 0.28 | 0.23 | FALSE |
| 3 | GTEx | Testis | AKTIP | 0.19 | 0.00 | enet | 26 | 0.00 | 1.9e-01 | 1.2 | 12.3 | 9.3e-35 | 0.51 | 0.03 | 0.40 | TRUE |
| 4 | The Cancer Genome Atlas | Glioblastoma Multiforme | FTO | 0.27 | 0.16 | enet | 13 | 0.14 | 6.7e-05 | -1.8 | 9.7 | 3.8e-22 | 0.33 | 0.11 | 0.32 | TRUE |