TWAS
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Genes
Traits
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Traits
:
Whole body fat mass
:
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chr17:27,222,988-29,547,601
Best TWAS P=1.34e-07 · Best GWAS P=4.41e-09 conditioned to 7.82e-06
27.5M
28M
28.5M
29M
29.5M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
The Cancer Genome Atlas
Colon Adenocarcinoma
CCDC55
0.15
0.01
blup
64
0.04
1.9e-03
-4.7
5.3
1.3e-07
0.31
0.02
0.49
TRUE
1
GTEx
Brain Cortex
GOSR1
0.20
0.20
enet
7
0.18
1.4e-05
4.5
5.1
2.8e-07
0.16
0.12
0.83
FALSE
2
GTEx
Thyroid
ANKRD13B
0.23
0.12
lasso
6
0.18
2.3e-13
-2.9
-5.1
3.1e-07
-0.73
0.03
0.97
FALSE