Best TWAS P=1.34e-07 · Best GWAS P=4.41e-09 conditioned to 7.82e-06
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Brain Cortex | GOSR1 | 0.20 | 0.20 | enet | 7 | 0.18 | 1.4e-05 | 4.5 | 5.1 | 2.8e-07 | 0.16 | 0.12 | 0.83 | FALSE |
2 | GTEx | Thyroid | ANKRD13B | 0.23 | 0.12 | lasso | 6 | 0.18 | 2.3e-13 | -2.9 | -5.1 | 3.1e-07 | -0.73 | 0.03 | 0.97 | FALSE |
3 | The Cancer Genome Atlas | Colon Adenocarcinoma | CCDC55 | 0.15 | 0.01 | blup | 64 | 0.04 | 1.9e-03 | -4.7 | 5.3 | 1.3e-07 | 0.31 | 0.02 | 0.49 | TRUE |