Best TWAS P=1.15e-08 · Best GWAS P=0.000664 conditioned to 0.0414
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 8 | GTEx | Skin Sun Exposed Lower leg | KANSL1 | 0.39 | 0.11 | enet | 20 | 0.16 | 6.8e-13 | 4.8 | -5.7 | 1.2e-08 | -0.25 | 0.00 | 0.99 | TRUE |
| 3 | GTEx | Cells Transformed fibroblasts | KANSL1 | 0.24 | 0.06 | lasso | 4 | 0.13 | 1.1e-09 | -3.3 | -5.7 | 1.3e-08 | -0.41 | 0.01 | 0.91 | FALSE |
| 2 | GTEx | Cells EBV-transformed lymphocytes | KANSL1 | 0.50 | 0.14 | lasso | 5 | 0.30 | 2.4e-10 | 4.8 | -5.4 | 5.2e-08 | -0.35 | 0.00 | 0.94 | FALSE |
| 5 | GTEx | Lung | KANSL1 | 0.34 | 0.07 | enet | 30 | 0.11 | 1.7e-08 | 4.8 | -5.4 | 7.3e-08 | -0.18 | 0.00 | 0.97 | FALSE |
| 6 | GTEx | Muscle Skeletal | KANSL1 | 0.10 | 0.05 | enet | 9 | 0.04 | 1.7e-04 | 4.8 | -5.3 | 1.1e-07 | -0.11 | 0.00 | 0.96 | FALSE |
| 1 | GTEx | Artery Tibial | KANSL1 | 0.31 | 0.07 | lasso | 6 | 0.07 | 1.7e-06 | 4.8 | -5.3 | 1.3e-07 | -0.09 | 0.00 | 0.99 | FALSE |
| 7 | GTEx | Ovary | KANSL1 | 0.15 | 0.04 | lasso | 3 | 0.10 | 2.1e-03 | 4.8 | -5.1 | 2.8e-07 | -0.10 | 0.00 | 0.26 | FALSE |
| 4 | GTEx | Esophagus Mucosa | KANSL1 | 0.23 | 0.08 | lasso | 3 | 0.08 | 9.3e-06 | 4.8 | -5.1 | 2.9e-07 | -0.13 | 0.00 | 0.98 | FALSE |